Fast Facts and Concepts #483: Commonly Used Supplements for Cancer-Related Symptom Management

Velicer CM , Ulrich CM . Vitamin and mineral supplement use among US adults after cancer diagnosis: A systematic review. J Clin Oncol, 2008; 26(4):665–673.

Du M , Luo H , Blumberg JB , et al. Dietary supplement use among adult cancer survivors in the United States. J Nutr, 2020; 150(6):1499–1508.

Ambrosone CB , Zirpoli GR , Hutson AD , et al. Dietary supplement use during chemotherapy and survival outcomes of patients with breast cancer enrolled in a cooperative group clinical trial (SWOG S0221). J Clin Oncol, 2020; 38(8):804–814.

Cassileth BR , Vickers AJ . High prevalence of complementary and alternative medicine use among cancer patients: Implications for research and clinical care. J Clin Oncol, 2005; 23(12):2590–2592.

Are Dietary Supplements Safe? [Internet]. [cited 2022 Nov 9]. Available from: https://www.cancer.org/treatment/treatments-and-side-effects/treatment-types/complementary-and-integrative-medicine/dietary-supplements/safety.html [Last accessed: April 1, 2024].

Barton DL , Liu H , Dakhil SR , et al. Wisconsin ginseng (Panax quinquefolius) to improve cancer-related fatigue: A randomized, double-blind trial, N07C2. J Natl Cancer Inst, 2013; 105(16):1230–1238.

Yuan CS , Wei G , Dey L , et al. Brief communication: American ginseng reduces warfarin’s effect in healthy patients: A randomized, controlled Trial. Ann Intern Med, 2004; 141(1):23–27.

Rao SSC , Brenner DM . Efficacy and safety of over-the-counter therapies for chronic constipation: An updated systematic review. Am J Gastroenterol, 2021; 116(6):1156–1181.

Garrison SR , Korownyk CS , Kolber MR , et al. Magnesium for skeletal muscle cramps. Cochrane Database Syst Rev, 2020; 9(9):CD009402.

Park H , Parker GL , Boardman CH , et al. A pilot phase II trial of magnesium supplements to reduce menopausal hot flashes in breast cancer patients. Support Care Cancer, 2011; 19(6):859–863.

Mah J , Pitre T . Oral magnesium supplementation for insomnia in older adults: A systematic review & meta-analysis. BMC Complement Med Ther, 2021; 21(1):125.

Teigen L , Boes CJ . An evidence-based review of oral magnesium supplementation in the preventive treatment of migraine. Cephalalgia, 2015; 35(10):912–922.

Sateia MJ , Buysse DJ , Krystal AD , et al. Clinical practice guideline for the pharmacologic treatment of chronic insomnia in adults: An american academy of sleep medicine clinical practice guideline. J Clin Sleep Med, 2017; 13(2):307–349.

Boafo A , Greenham S , Alenezi S , et al. Could long-term administration of melatonin to prepubertal children affect timing of puberty? A clinician’s perspective. Nat Sci Sleep, 2019; 11:1–10.

Grigg-Damberger MM , Ianakieva D . Poor quality control of over-the-counter melatonin: What they say is often not what you get. J Clin Sleep Med, 2017; 13(2):163–165.

Lam CN , Watt AE , Isenring EA , et al. The effect of oral omega-3 polyunsaturated fatty acid supplementation on muscle maintenance and quality of life in patients with cancer: A systematic review and meta-analysis. Clin Nutr, 2021; 40(6):3815–3826.

Loprinzi CL , Lacchetti C , Bleeker J , et al. Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: ASCO guideline update. J Clin Oncol, 2020; 38(28):3325–3348.

Shen S , Unger JM , Crew KD , et al. Omega-3 fatty acid use for obese breast cancer patients with aromatase inhibitor-related arthralgia (SWOG S0927). Breast Cancer Res Treat, 2018; 172(3):603–610.

Buckley MS , Goff AD , Knapp WE . Fish oil interaction with warfarin. Ann Pharmacother, 2004; 38(1):50–52.

Shenouda M , Copley R , Pacioles T , et al. Effect of tart cherry on Aromatase Inhibitor-Induced Arthralgia (AIA) in nonmetastatic hormone-positive breast cancer patients: A randomized double-blind placebo-controlled trial. Clin Breast Cancer, 2022; 22(1):e30-6–e36.

Chung J , Choi M , Lee K . Effects of short-term intake of montmorency tart cherry juice on sleep quality after intermittent exercise in elite female field hockey players: A randomized controlled trial. Int J Environ Res Public Health, 2022; 19(16):10272.

Peng Y , Ao M , Dong B , et al. Anti-inflammatory effects of curcumin in the inflammatory diseases: Status, limitations and countermeasures. Drug Des Devel Ther, 2021; 15:4503–4525.

PDQ Integrative, Alternative, and Complementary Therapies Editorial Board. Curcumin (Curcuma, Turmeric) and Cancer (PDQ^®): Health Professional Version. In: PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002 [cited 2023 Jan 17]. Available from: http://www.ncbi.nlm.nih.gov/books/NBK568018/

Tang M , Larson-Meyer DE , Liebman M . Effect of cinnamon and turmeric on urinary oxalate excretion, plasma lipids, and plasma glucose in healthy subjects. Am J Clin Nutr, 2008; 87(5):1262–1267.

Yeung KS , Hernandez M , Mao JJ , et al. Herbal medicine for depression and anxiety: A systematic review with assessment of potential psycho-oncologic relevance. Phytother Res, 2018; 32(5):865–891.

Shinjyo N , Waddell G , Green J . Valerian root in treating sleep problems and associated disorders-a systematic review and meta-analysis. J Evid Based Integr Med, 2020; 25:2515690X20967323.

Douros A , Bronder E , Andersohn F , et al. Drug-induced acute pancreatitis: Results from the hospital-based Berlin case-control surveillance study of 102 cases. Aliment Pharmacol Ther, 2013; 38(7):825–834.

Cohen DL , Del Toro Y . A case of valerian-associated hepatotoxicity. J Clin Gastroenterol, 2008; 42(8):961–962.