Intraperitoneal chemotherapy poses both potential benefits as a cancer treatment and negative consequences on patient and family quality of life.
The profound multi-dimensional quality of life impact of intraperitoneal (IP) chemotherapy upon women with advanced ovarian cancer makes the early integration of palliative care particularly important for this population.
Numerous opportunities occur throughout the treatment process to improve the delivery of biopsychosocial-spiritual support to women receiving IP chemotherapy.
Get full access to this article
View all access options for this article.
References
1.
ArribaLN, FaderAN, FrasureHE, von GruenigenVE. A review of issues surrounding quality of life among women with ovarian cancer. Gynecologic Oncology, 2010; 119:390–396.
2.
American Cancer Society. Cancer Facts and Figures. Atlanta, GA, 2012.
3.
Arden-CloseA, GidronY, Moss-MorrisR. Psychological distress and its correlates in ovarian cancer: A systematic review. Psychooncology, 2008; 17:1061–1072.
4.
FerrellB, SmithS, CullinaneC, MelanconC. Symptom concerns of women with ovarian cancer. J Pain Symptom Manage, 2003; 25:528–538.
5.
FerrellBR, SmithSL, ErvinKS, ItanoJ, MelanconC. A qualitative analysis of social concerns of women with ovarian cancer. Psychooncology, 2003; 12:647–663.
6.
FitchMI, GrayRE, FranssenE. Women's perspectives regarding the impact of ovarian cancer. Cancer Nurs, 2000; 23:359–365.
7.
FitchMI, GrayRE, FranssenE. Perspectives on living with ovarian cancer: Older women's views. Oncol Nurs Forum, 2001; 28:1433–1442.
8.
FoxSW, LyonD. Symptom clusters and quality of life in survivors of ovarian cancer. Cancer Nurs, 2007; 30:354–361.
9.
ArmstrongD, BundyB, WenzelL, HuangHQ, BaergenR, LeleS, CopelandLJ, WalkerJL, BurgerRA. Gynecologic Oncology group. Intraperitoneal cisplatin and paclitaxel in ovarian cancer. New Engl J Med, 2006; 354:34–43.
10.
TuttleT, ZhangY, GreenoE, KnutsenA. Toxicity and quality of life after cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy. Ann Surg Oncol, 2006; 13:1627–1632.
11.
HydzikC. Implementation of intraperitoneal chemotherapy for the treatment of ovarian cancer. Clin J Oncol Nurs, 2007; 11:221–225.
12.
HydzikC. Treatment of ovarian cancer with intraperitoneal chemotherapy. ONCOLOGY Nurse Edition, 2009; 23:15–20.
RaoG, CrispensM, RothenbergML. Intraperitoneal chemotherapy for ovarian cancer: Overview and perspective. J Clin Oncol, 2007; 25:2867–2872.
15.
National Consensus Project. Clinical Practice Guidelines for Quality Palliative Care, 2nd. Pittsburgh, PA: National Consensus Project, 2009.
16.
WeissmanDE, MeierDE, SpragensLH. Center to Advance Palliative Care: Palliative care consultation service metrics: Consensus recommendations. J Palliat Med, 2008; 11:1294–1298.
17.
BakitasM, LyonsKD, HegelMT, BalanS, BrokawFC, SevilleJ, HullJG, TostesonTD, ByockIR, AhlesTA. Effects of a palliative care intervention on clinical outcomes in patients with advanced cancer: The Project ENABLE II randomized controlled trial. JAMA, 2009; 302:741–749.
18.
MitkaM. Cancer experts recommend introducing palliative care at time of diagnosis. JAMA, 2012; 307:1241–1242.
19.
FieldMJ, CasselCK. Approaching Death: Improving Care at the End of Life. [Report of the Institute of Medicine Task Force]Washington, DC: National Academies Press, 1997.
20.
WakabayashiMT, Otis-GreenS, FerrellB, MorganR, HakimAA, SalmonL, NguyenK, GrantM. Integration of palliative care during the administration of intraperitoneal chemotherapy for ovarian cancer. Gynecol Oncol, 2009; 112:S164.
21.
EkwallE, TernestedtB, SorbeB. Recurrence of ovarian cancer: Living in limbo. Cancer Nurs, 2007; 30:270–277.
22.
WenzelLB, HuangHQ, ArmstrongDK, WalkerJL, CellaD. Health-related quality of life during and after intraperitoneal versus intravenous chemotherapy for optimally debulked ovarian cancer: A gynecologic oncology group study. J Clin Oncol, 2007; 25:437–443.
23.
HerzogT, PothuriB. Ovarian cancer: A focus on management of recurrent disease. Nat Clin Pract Oncol, 2006; 3:604–611.
24.
GrzankowskiKS, CarneyM. Quality of life in ovarian cancer. Cancer Control, 2011; 18:52–58.
25.
LoweT, FerrellB, LeongL. Quality-of-life issues in the management of epithelial ovarian cancer. Current Treatment Options in Oncology, 2007; 8:402–416.
26.
CreswellJW, KlassenAC, Plano ClarkVL. for the Office of Behavioral and Social Sciences Research. Best Practices for Mixed Methods Research in the Health Sciences. Washington, DC: National Institutes of Health, 2011. obssr.od.nih.gov/mixed_methods_research. 2012 June 15.
27.
GemmillR, WilliamsAC, CookeL, GrantM. Challenges and strategies for recruitment and retention of vulnerable research participants: Promoting the benefits of participation. Applied Nursing Research, 2012; 25:101–107.
28.
SunV, Otis-GreenS, MorganR, WakabayashiM, HakimA, ColladoME, YangE, FerrellB, GrantM. Toxicities, complications, resource utilization during intraperitoneal chemotherapy in ovarian cancer. Cancer Nursing (in review).
29.
ErsekM, FerrellBR, DowKH, MelanconCH. Quality of life in women with ovarian cancer. West J Nurs Res, 1997; 19:334–350.
30.
Basen-EnquisK, Bodurka-BeversD, FitzgeraldMA, WebsterK, CellaD, HuS, GershensonDM. Reliability and validity of the Functional Assessment of Cancer Therapy-Ovarian (FACT-O)J Clin Oncol, 2001; 19:1809–1817.
31.
PuchalskiCM, RomerAL. Taking a spiritual history allows clinicians to understand patients more fully. J Palliat Med, 2000; 3:129–137.
32.
BornemanT, FerrellB, PuchalskiCM. Evaluation of the FICA tool for spiritual assessment. J Pain Symptom Manage, 2010; 40:163–173.
33.
BradwayC, TrottaR, BixbyMB, McPartlandE, WollmanMC, KapustkaH, McCauleyK, NaylorMD. A qualitative analysis of an advanced practice nurse-directed transitional care model intervention. The Gerontologist, 2011; 52:394–407.
34.
HsiehHF, ShannonSE. Three approaches to qualitative content analysis. Qual Health Res, 2005; 9:1277–1288.
35.
ZhangY, WildemuthBM. Qualitative analysis of content. WildemuthBM. Applications of Social Research Methods to Questions in Information and Library Science. Westport, CT: Libraries Unlimited, 2009; 308–319.
36.
MacDonaldDJ, SarnaL, UmanGC, GrantM, WeitzelJN. Cancer screening and risk reducing behaviors of women seeking genetic cancer risk assessment for breast and ovarian cancers. Oncol Nurs Forum, 2006; 33:E27–E35.
37.
PuchalskiC, FerrellB, ViraniR, Otis-GreenS, BairdP, BullJ, ChochinovH, HandzoG, Nelson-BeckerH, Pince-PaulM, PuglieseK, SulmasyD. Special Report: Improving the quality of spiritual care as a dimension of palliative care: The report of the Consensus Conference. J Palliat Med, 2009; 12:885–905.
38.
ColuzziPH, GrantM, DoroshowJH, RhinerM, FerrellB, RiveraL. Survey of the provision of supportive care services at National Cancer Institute-designated cancer centers. J Clin Oncol, 1995; 13:756–764.
39.
HuiD, ElsayemA, De La CruzM, BergA, ZhukovskyDS, PallaS, EvansA, FadulN, PalmerJL, BrueraE. Availability and integration of palliative care at US cancer centers. JAMA, 2010; 303:1054–1061.
40.
Institute of Medicine. Cancer care for the whole patient: Meeting psychosocial health needs. Washington, DC: The National Academies Press, 2008.
41.
FerrellB, CullinaneCA, ErvineK, MelanconC, UmanGC, JuarezG. Perspectives on the impact of ovarian cancer: Women's views of quality of life. Oncol Nurs Forum, 2005; 32:1143–1149.
42.
SunCC, RamirezPT, BodurkaDC. Quality of life for patients with epithelial ovarian cancer. Nat Clin Prac Oncol, 2007; 4:18–29.
43.
SteeleR, FitchMI. Supportive care needs of women with gynecologic cancer. Cancer Nursing, 2008; 31:284–291.
44.
TemelJS, GreerJA, MuzikanskyA, GallagherER, AdmaneS, JacksonVA, DahlinCM, BlindermanCD, JacobsenJ, PirlWF, BillingsJA, LynchTJ. Early palliative care for patients with metastatic non-small-cell lung cancer. New Engl J Med, 2010; 363:733–742.
45.
Otis-GreenS, FerrellB, SunV, SpolumM, MorganR, MacDonaldD. Feasibility of an ovarian cancer quality-of-life psychoeducational intervention. J Cancer Edu, 2008; 23:214–221.
46.
MarkmanM, WalkerJL. Intraperitoneal chemotherapy of ovarian cancer: A review, with a focus on practical aspects of treatment. J Clin Oncol, 2006; 24:988–994.
47.
ElitL, Fung-Kee-FungM, OliverTK, JolicoeurL, LeT. Intraperitoneal chemotherapy for women with stage III epithelial ovarian cancer: Improving survival outcomes for patients. Am J Hematol Oncol, 2007; 6:459–464.
48.
SmithTJ, TeminS, AlesiER, AbernathyAP, BalboniTA, BaschEM, FerrellBR, LoscalzoM, MeierDE, PaiceJA, PeppercornJM, SomerfieldM, StovallE, Von RoennJH. American Society of Clinical Oncology Provisional Clinical Opinion: The integration of palliative care into standard oncology care. J Clin Oncol, 2012; 30:880–887.
