Purpose: The aim of this study is to report on the clinical course of a patient showing
markedly increased intraocular pressure (IOP) caused by intravitreal triamcinolone acetonide.
Methods: A 33-year-old patient received an intravitreal injection of approximately 20 mg of
triamcinolone acetonide (TA) as treatment of otherwise therapy-resistant uveitis. She experienced
an IOP rise to values over 40 mmHg for a period for more than 3 months, despite maximal
antiglaucomatous medical therapy. Peak IOP was 55 mmHg.
Results: Neither confocal scanning laser tomography nor qualitative assessment of optic
disc photographs nor perimetry showed development of glaucomatous changes. Scanning
laser polarimetry of the retinal nerve fiber layer suggested a slight loss in the nasal upper
fundus quadrant.
Conclusions: Relatively young patients with a pronounced TA-induced rise in IOP, unresponsive to maximal antiglaucomatous medication, may not necessarily undergo antiglaucomatous
surgery if the rise in IOP does not last longer than approximately 3 months.
