Acmella oleracea Is a Medicinal Plant That Decreases Chymase Activity,Oxidative Stress,and Inflammation: Possible Role in the Adjuvant Treatment of COVID-19
Restricted accessLetterFirst published online November, 2021
Acmella oleracea Is a Medicinal Plant That Decreases Chymase Activity,Oxidative Stress,and Inflammation: Possible Role in the Adjuvant Treatment of COVID-19
SteinR, BergerM, Santana de CeccoB, MallmannLP, TerracianoPB, DriemeierD, RodriguesE, Beys-da-SilvaWO, KonrathEL: Chymase inhibition: A key factor in the anti-inflammatory activity of ethanolic extracts and spilanthol isolated from Acmella oleracea. J Ethnopharmacol, 2021; 270:113610.
2.
LanJ, GeJ, YuJ, ShanS, ZhouH, FanS, ZhangQ, ShiX, WangQ, ZhangL, WangX: Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor. Nature, 2020; 581:215–220.
3.
TamargoM, TamargoJ: Future drug discovery in renin-angiotensin-aldosterone system intervention. Expert Opin Drug Discov, 2017; 12:827–848.
4.
SantosRA, FerreiraAJ, Simões e SilvaAC: Recent advances in the angiotensin-converting enzyme 2-angiotensin (1-7)-Mas axis. Exp Physiol, 2008; 93:519–527.
5.
MascoloA, ScavoneC, RafanielloC, FerrajoloC, RacagniG, BerrinoL, PaolissoG, RossiF, CapuanoA: Renin-angiotensin system and coronavirus disease 2019: A narrative review. Front Cardiovasc Med, 2020; 7:143.
