ZhangF, BasinskiMB, BealsJMet al.Crystal structure of the obese protein leptin-E100. Nature, 1994; 387:206–209.
2.
ConsidineRV, SinhaMK, HeimanMLet al.Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med, 1996; 334:292–295.
3.
ChoiYS, ParkSY, KimJYet al.Combined treatment of betulinic acid, a PTP1B inhibitor, with Orthosiphon stamineus extract decreases body weight in high fat-fed mice. J Med Food, 2013; 16:2–8.
4.
ElcheblyM, PayetteP, MichaliszynEet al.Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene. Science, 1999; 283:1544–1548.
5.
WhiteCL, WhittingtonA, BarnesMJ, WangZ, BrayGA, MorrisonCD. HF diets increase hypothalamic PTPB1 and induce leptin resistance through both leptin-dependent and -independent mechanisms. Am J Physiol Endocrinol Metab, 2009; 296:E291–E299.
