Abstract
Cardiovascular disease is the number one cause of death in the United States. Cholesterollowering drugs and dietary and behavioral modifications have been the traditional choice of treatment for the disease. Recently, there has been an increased advocacy for the use of antioxidants to retard the progression of the disease. In this review, the role of oxidants in the promotion of cardiovascular disease and the means by which antioxidants may prevent the disease are outlined. Specifically, multiple pathways by which antioxidants may retard the progression of cardiovascular disease are described.
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