Abstract
Fourteen evaluable patients with diffuse malignant mesothelioma were treated with a once-a-day for 5 days out of 7 for 6 weeks regimen of recombinant interferon-β (IFN-βser). No responses were noted. The major toxicities included fever, chills, nausea, vomiting, and anorexia. IFN-βser at this dose and schedule does not appear to be an active single agent for patients with refractory malignant mesothelioma.
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