JinekM, ChylinskiK, FonfaraI, et al.A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science, 2012; 337(6096):816–821; doi: 10.1126/science.1225829
2.
RanFA, HsuPD, WrightJ, et al.Genome engineering using the CRISPR-Cas9 system. Nat Protoc, 2013; 8(11):2281–2308; doi: 10.1038/nprot.2013.143
3.
KomorAC, KimYB, PackerMS, et al.Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage. Nature, 2016; 533(7603):420–424; doi: 10.1038/nature17946
4.
GaudelliNM, KomorAC, ReesHA, et al.Programmable base editing of A*T to G*C in genomic DNA without DNA cleavage. Nature, 2017; 551(7681):464–471; doi: 10.1038/nature24644
5.
AnzaloneAV, RandolphPB, DavisJR, et al.Search-and-replace genome editing without double-strand breaks or donor DNA. Nature, 2019; 576(7785):149–157; doi: 10.1038/s41586-019-1711-4
6.
LiuQ, ChenY, HuS, et al.Screening an effective dual-AAV split-CBE system for C-to-T conversion in vivo. Hum Gene Ther, 2023; In Press; doi: 10.1089/hum.2023.055
7.
LiR, JingQ, SheK, et al.Split AAV8 mediated ABCA4 expression for gene therapy of Mouse Stargardt Disease (STGD1). Hum Gene Ther, 2023; In Press; doi: 10.1089/hum.2023.017
8.
ChenL, ParkJE, PaaP, et al.Programmable C:G to G:C genome editing with CRISPR-Cas9-directed base excision repair proteins. Nat Commun, 2021; 12(1):1384; doi: 10.1038/s41467-021-21559-9
9.
ChenL, HongM, LuanC, et al.Adenine transversion editors enable precise, efficient A*T-to-C*G base editing in mammalian cells and embryos. Nat Biotechnol, 2023; In Press; doi: 10.1038/s41587-023-01821-9
10.
GramespacherJA, StevensAJ, ThompsonRE, et al.Improved protein splicing using embedded split inteins. Protein Sci, 2018; 27(3):614–619; doi: 10.1002/pro.3357
11.
SchmelasC, GrimmD. Split Cas9, not hairs—Advancing the Therapeutic Index of CRISPR Technology. Biotechnol J, 2018; 13(9):e1700432; doi: 10.1002/biot.201700432
12.
KarvelisT, BigelyteG, YoungJK, et al.PAM recognition by miniature CRISPR-Cas12f nucleases triggers programmable double-stranded DNA target cleavage. Nucleic Acids Res, 2020; 48(9):5016–5023; doi: 10.1093/nar/gkaa208
13.
SasnauskasG, TamulaitieneG, DruteikaG, et al.TnpB structure reveals minimal functional core of Cas12 nuclease family. Nature, 2023; 616(7956):384–389; doi: 10.1038/s41586-023-05826-x
