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References
1.
Ang
SO
,
Chen
H
,
Hirota
K
,
Gordeuk
VR
,
Jelinek
J
,
Guan
Y
,
Liu
E
,
Sergueeva
AI
,
Miasnikova
GY
,
Mole
D
,
Maxwell
PH
,
Stockton
DW
,
Semenza
GL
,
Prchal
JT
. (2002 ). Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia . Nat Genet , 32 :614 –621 .
2.
Haase
VH
. (2013 ). Regulation of erythropoiesis by hypoxia-inducible factors . Blood Rev , 27 :41 –53 .
3.
Lorenzo
FR
,
Huff
C
,
Myllymaki
M
,
Olenchock
B
,
Swierczek
S
,
Tashi
T
,
Gordeuk
V
,
Wuren
T
,
Ri-Li
G
,
McClain
DA
,
Khan
TM
,
Koul
PA
,
Guchhait
P
,
Salama
ME
,
Xing
J
,
Semenza
GL
,
Liberzon
E
,
Wilson
A
,
Simonson
TS
,
Jorde
LB
,
Kaelin
WG
Jr
,
Koivunen
P
,
Prchal
JT
. (2014 ). A genetic mechanism for Tibetan high-altitude adaptation . Nat Genet , 46 :951 –956 .
4.
Rogers
SC
,
Said
A
,
Corcuera
D
,
McLaughlin
D
,
Kell
P
, and
Doctor
A
. (2009 ). Hypoxia limits antioxidant capacity in red blood cells by altering glycolytic pathway dominance . FASEB J , 23 :3159 –3170 .
5.
Song
J
,
Yoon
D
,
Christensen
RD
,
Horvathova
M
,
Thiagarajan
P
, and
Prchal
JT
. (2015 ). HIF-mediated increased ROS from reduced mitophagy and decreased catalase causes neocytolysis . J Mol Med (Berl) , 93 :857 –866 .
6.
Van Putten
LM
. (1958 ). The life span of red cells in the rat and the mouse as determined by labeling with DFP32 in vivo . Blood , 13 :789 –794 .
