Restricted accessCase reportFirst published online 2018-12
Primary Vaginal Small-Cell Carcinoma Treated with Concurrent Chemoradiotherapy and Interstitial Irradiation: A Case Report and Review of the Literature
Primary vaginal small-cell neuroendocrine carcinoma (VSC) is extremely rare and is associated with a poor prognosis. Treatment of VSC differs by institute, and optimal treatment strategies remain unclear.
Case:
A 54-year-old woman, who had a surgical history of hysterectomy due to myoma at the age of 37, was diagnosed as having VSC carcinoma. Her staging was designated as AJCC [American Joint Committee on Cancer] pathologic stage III (T1 N1 M0). Concurrent chemoradiation therapy (CCRT) with interstitial irradiation was selected for the treatment.
Results:
After CCRT, she did not show any evidence of recurrence.
Conclusions:
CCRT with interstitial irradiation was effective for treating VSC carcinoma in an advanced stage.
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