A Case of High-Grade Endometrial Stromal Sarcoma with Concurrent Pregnancy

Abstract

Abstract

Background:

High-grade endometrial stromal sarcomas (HGESS) are very rare uterine tumors, and HGESS during pregnancy is exceedingly rare. This is the first-ever published case of a uterine sarcoma with a concurrent pregnancy that was treated successfully with surgery and adjuvant chemotherapy.

Case:

A 24-year-old, gravida 1, female at 12 weeks of gestational age presented with vaginal bleeding and was found to have a cervical polyp with spindle-cell malignancy on biopsy. The patient underwent a hysterectomy, bilateral salpingectomy, and lymph node dissection with ovarian preservation.

Results:

Pathology was diagnostic of HGESS. The patient received adjuvant chemotherapy and remained in remission 15 months postoperatively.

Conclusions:

Surgery and adjuvant chemotherapy should be strongly considered for the treatment of HGESS during pregnancy. Ovarian preservation should be considered for patients desiring future fertility. (J GYNECOL SURG 34:105)