Squamous-Cell Carcinoma Arising from an Epidermoid Cyst of the Ovary and Metastasizing to the Uterus: Report of an Unusual Case with Review of Literature

Abstract

Abstract

Background:

Squamous-cell carcinoma (SCC) of the ovary arising from an epidermoid cyst is an exceptionally rare occurrence. SCC presenting with a metastatic nodule in the myometrium has not yet been reported in literature. Most commonly, SCC arises from mature cystic teratomas of the ovaries. It presents with nonspecific signs and symptoms in postmenopausal females.

Case:

This article reports on a case of pure SCC of the ovary with metastasis to the myometrium in a 55-year-old postmenopausal female that was diagnosed on a histopathologic examination.

Results:

Histopathologic examination led to the diagnosis of well-differentiated SCC originating from the epidermoid cyst of the ovary and metastasizing to the uterus.

Conclusions:

Preoperative radiologic diagnosis is challenging; hence, postoperative histopathologic examination is essential for a final diagnosis. Serum markers, such as SCC antigen and CA-125, help in making a provisional diagnosis of SCC. Due to the rarity of such cases in the literature, treatment options are not clearly understood. (J GYNECOL SURG 33:156)