Background: Epidermoid cysts are slow-growing, intradermal or subcutaneous tumors with a wall composed of true epidermis. Case: A 50-year-old multiparous female presented with a complaint of a slow-growing swelling in the pubic region of 6 months' duration. On examination, a painless cystic mobile mass was noted. It extended from the clitoral region up to the labia minora, having a diameter of 5×6 cm in the clitoral region, with regular margins and a smooth surface. The patient was scheduled for surgical enucleation of the cyst. Results: On the second postoperative day, a small hematoma was observed, which was removed after cutting one stitch. The patient was discharged on the fourth postoperative day. The histopathology report revealed an epidermoid cyst lined by stratified squamous epithelium filled with keratinous material. At a follow-up visit after 2 weeks, the patient was comfortable and her stitch line was healthy. Conclusions: Clitoral epidermoid cysts should be differentiated from many other pathologies of the clitoris with an accurate clinical evaluation and surgical management. (J GYNECOL SURG 30:61)
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