Background: A uterine angioleiomyoma along with coexisting hypofibrinogenemia is a extremely rare clinical presentation. Case: A 37-year-old women presented with recent-onset menorrhagia and an abdominopelvic mass. She had a history of easy bruising and an increased tendency toward excessive bleeding, both of which started 6 months prior to presentation. Ultrasonography scanning revealed the presence of an 18×18 cm mass in the posterior wall; this mass was a degenerating leiomyoma. The patient's coagulation profile revealed coexisting hypofibrinogenemia. After adequate hematologic support, this patient underwent a myomectomy. During the surgery and postoperatively, she received additional cryoprecipitate support. Results: Her recovery was uneventful. Her coagulation abnormalities were resolved postoperatively. Conclusions: Similar cases of benign uterine tumors associated with hematologic abnormalities, resolving postoperatively after removal of such tumors have been reported. A recent onset of unusual bleeding tendencies and a coexisting benign uterine tumor should alert the clinician regarding a possible link between the two pathologies and the need for a multidisciplinary approach for managing such cases. (J GYNECOL SURG 30:50)
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