Background: Urethrovaginal fistula (UVF) is a rare condition, but remains one of the main concerns in the field of female urology. The conventional treatment is open surgery, which is a difficult and invasive method and has various complications. Autologous platelet-rich plasma (PRP) and platelet-rich fibrin glue (PRFG) have been used for UVF closure as a minimally invasive approach. Case: The case of a 32-year-old woman with a UVF, which developed after a cesarean delivery, is reported in this article. The method used (Hamidi–Shirvan method) has been performed for UVF treatment. Results: No complications were observed during and after the injection. At a 6-months follow-up, the patient considered herself clinically cured. Conclusions: This approach obviates the need for open surgery. (J GYNECOL SURG 29:268)
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