Leiomyo-Adenomatoid Tumor of the Uterus: Report of a Rare Entity

Abstract

Abstract

Background: A leiomyo-adenomatoid tumor in the anterior cervico-corporal junction of the uterus is reported in this article. Five previous cases in the uterus and 1 in the epididymis have been reported to date. Case: A 24-year-old woman presented with a sense of cervical descent and occasional dyspareunia among other symptoms. Transvaginal ultrasonography showed a 26×23–mm myoma, which was surgically removed. A microscopic examination revealed a myoma with an adenomatoid component intermingled between the smooth-muscle fascicles, consisting of groups of vacuolated cells, slit-like structures, and tubules lined by flattened-to-cuboidal cells with small and uniform nuclei, some with an apical brush border. Immunohistochemistry confirmed the diagnosis leiomyo-adnomatoid tumor of the uterus. Results: While the pathologic changes found represented a leiomyo-adenomatoid tumor of her uterus, she recovered from surgery and her symptoms were resolved. Conclusions: The coexistence of the tumor components favors the hypothesis that a leiomyo-adenomatoid tumor should be considered to be a specific subtype of adenomatoid tumor, and not a collision tumor. (J GYNECOL SURG 29:219)