Total Abdominal Hysterectomy May Be a Risk Factor for Acute Myocardial Infarction in Postmenopausal Women: An Age-Matched,Case-Controlled Retrospective Analysis

Abstract

Objective: To investigate the risk factors for acute myocardial infarction (AMI) in postmenopausal women in comparison to age-matched controls by retrospective analysis. Methods: This study was conducted retrospectively on 105 postmenopausal women who were diagnosed and treated for AMI in our hospital in comparison with age-matched women who had received health testing and screening. The odds ratios for six factors were calculated. The factors were hypertension, hyperlipidemia, diabetes mellitus (DM), smoking, obesity, and total abdominal hysterectomy. Results: Among 105 subjects in whom AMI occurred, smoking was the highest risk factor for AMI. Hyperlipidemia and diabetes were the next most common risk factors for AMI. Eighteen subjects (17.1%) had a past history of total abdominal hysterectomy. The odds ratio for hysterectomy and AMI was 3.591. Conclusions: Smoking may be the highest risk factor for AMI in postmenopausal women. Total abdominal hysterectomy was also identified to be the risk factor for AMI. (J GYNECOL SURG 20:75)