Abstract
ABSTRACT
Our purpose was to evaluate the amount of blood loss in patients who underwent loop excision of the transformation zone by infiltrating the ectrocervix with a 1:30 POR8-lignocaine 1% 30-ml solution. Ninety women undergoing loop excision of the transformation zone for cervical intraepithelial neoplasia were randomly allocated to one of three groups: A, POR8-lignocaine group; B, lignocaine group; and C, epinephrine-lignocaine group). A standard protocol, which included operative technique, estimation of blood loss, operative time, pain, and morbidity, was used. Statistical analysis was performed using Student's t test, chi-square, and the Fisher exact test. The use of 1:30 POR8 lignocaine 1% 30-ml solution resulted in less intraoperative blood loss (2.9 ± 1.2 vs. 6.4 ± 1.8 vs. 4.1 ± 1.2, p < 0.001). The operative time was 3.4 ± 1.22 min in the POR8 group vs. 5.63 ± 1.15 in group B and 4.23 ± 1 in group C. The dimensions of the excised specimens were similar. As for the pain experienced, no statistical difference was found in the three groups. No electrocardiographic anomaly was recorded. Blood pressure was moderately elevated in the POR8 group. Infiltration of the ectocervix with 30 ml 1:30 POR8-lignocaine 1% reduced the amount of blood loss during loop excision of the transformation zone. (J GYNECOL SURG 14:75, 1998).
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