Abstract
ABSTRACT
Sertoli-Leydig cell tumors are extremely rare, and their exact cellular origin is still debated. About 10% of these tumors occur in women over 45 years old. A 65-year-old woman had signs of virilization. Hormone assays revealed significantly elevated total and free testosterone, which was not suppressed by dexamethasone. Gynecologic examination revealed no enlargement of the adnexa. It was, nevertheless, decided to perform laparoscopic bilateral adnexectomy with vaginal hysterectomy and correction of an anteroposterior colpocele. Histologic examination led to a diagnosis of type 1 well-differentiated Sertoli-Leydig cell tumor of the left ovary with a maximum diameter of 2.2 cm. The postoperative course was normal, 20-month follow-up is negative, the signs of virilization have regressed well, and testosterone levels are within the normal range. Laparoscopic removal of the adnexa with vaginal hysterectomy can be a useful approach to the surgical treatment of sex cord stromal tumors in postmenopausal women. (J GYNECOL SURG 13:39, 1997)
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