Abstract
ABSTRACT
Forty-five patients in whom evidence of human papillomavirus (HPV) infection of the cervix was provided by the presence of koilocytes on biopsy, were monitored by regular cytological and colposcopic examinations.
On repeat biopsy 4 were found to have cervical intraepithelial neoplasia (CIN). Of the remaining 41 patients, 15 continue to have either abnormal cytology or colposcopically atypical epithelium after a median follow-up of 33 months, but 26 (58%) are cytologically and colposcopically free of disease after a median follow-up of 28 months.
It is concluded that cytological and colposcopic abnormalities associated with cervical HPV infection frequently undergo spontaneous resolution.
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