Restricted accessResearch articleFirst published online 2017-05
Retracted: Single Nucleotide Polymorphisms in the PTPN1 Gene Are Associated with Susceptibility to Esophageal Squamous Cell Carcinoma: A Case-Control Study in Inner Mongolia,China
officially retracts the article entitled, “Single Nucleotide Polymorphisms in the PTPN1 Gene Are Associated with Susceptibility to Esophageal Squamous Cell Carcinoma: A Case-Control Study in Inner Mongolia, China,” by Hong-Bo Ji, Le-Le Wang, Xiao-Ying Wang, Sheng-Jie Yin, Di Shang, Li-Li Sun, and Lei Wang (Genet Test Mol Biomarkers, 21(5):305-311; DOI: 10.1089/gtmb.2016.0194) at the request of the corresponding author, Dr. Lei Wang, who explained that, “my subsequent research has overturned my original research” and asked to “remove this inaccurate result...so as to avoid bringing troubles to other researchers.”
Though Dr. Wang nor any of his coauthors have not responded to numerous requests for more detailed information, the Editor of Genetic Testing and Molecular Biomarkers determined that the article should not remain in the literature due to the potential problems surrounding the results.
The Editor and Publisher of Genetic Testing and Molecular Biomarkers are committed to preserving the scientific literature and the community it serves.
Get full access to this article
View all access options for this article.
References
1.
AbnetCC, WangZ, SongX, et al. (2012) Genotypic variants at 2q33 and risk of esophageal squamous cell carcinoma in China: a meta-analysis of genome-wide association studies. Hum Mol Genet, 21:2132-2141.
2.
BalavenkatramanKK, AcetoN, BritschgiA, et al. (2011) Epithelial protein-tyrosine phosphatase 1B contributes to the induction of mammary tumors by HER2/Neu but is not essential for tumor maintenance. Mol Cancer Res, 9:1377-1384.
3.
BealesIL, Garcia-MoralesC, OgunwobiOO, et al. (2014) Adiponectin inhibits leptin-induced oncogenic signalling in oesophageal cancer cells by activation of PTP1B. Mol Cell Endocrinol, 382:150-158.
4.
ChaudharyR, SinghB, KumarM, et al. (2015) Role of single nucleotide polymorphisms in pharmacogenomics and their association with human diseases. Drug Metab, Rev: 1-10.
5.
ChungCS, LeeYC, WangCP, et al. (2010) Secondary prevention of esophageal squamous cell carcinoma in areas where smoking, alcohol, and betel quid chewing are prevalent. J Formos Med Assoc, 109:408-421.
6.
DaiN, ZhengM, WangC, et al. (2014) Genetic variants at 8q24 are associated with risk of esophageal squamous cell carcinoma in a Chinese population. Cancer Sci, 105:731-735.
7.
DenlingerCE, ThompsonRK (2012) Molecular basis of esophageal cancer development and progression. Surg Clin North Am, 92:1089-1103.
8.
FanG, LinG, LucitoR, et al. (2013) Protein-tyrosine phosphatase 1B antagonized signaling by insulin-like growth factor-1 receptor and kinase BRK/PTK6 in ovarian cancer cells. J Biol Chem, 288:24923-24934.
9.
GaoYB, ChenZL, LiJG, et al. (2014) Genetic landscape of esophageal squamous cell carcinoma. Nat Genet, 46:1097-1102.
10.
GuP, JiangW, DuH, et al. (2010) Protein tyrosine phosphatase 1B gene polymorphisms and essential hypertension: a case-control study in Chinese population. J Endocrinol Invest, 33:483-488.
11.
HermanssonM, DeMeesterSR (2012) Management of stage 1 esophageal cancer. Surg Clin North Am, 92:1155-1167.
12.
LessardL, StuibleM, TremblayML (2010) The two faces of PTP1B in cancer. Biochim Biophys Acta, 1804:613-619.
13.
MaoWM, ZhengWH, LingZQ (2011) Epidemiologic risk factors for esophageal cancer development. Asian Pac J Cancer Prev, 12:2461-2466.
14.
MoJ, WuJ, SunZ, et al. (2010) Association of PTP1B gene polymorphism with obesity in Chinese children. Zhong Nan Da Xue Xue Bao Yi Xue Ban, 35:915-920.
15.
MotiwalaT, JacobST (2006) Role of protein tyrosine phosphatases in cancer. Prog Nucleic Acid Res Mol Biol, 81:297-329.
OlivierM, HsiungCA, ChuangLM, et al. (2004) Single nucleotide polymorphisms in protein tyrosine phosphatase 1beta (PTPN1) are associated with essential hypertension and obesity. Hum Mol Genet, 13:1885-1892.
18.
RadojicicJ, ZaravinosA, SpandidosDA (2012) HPV, KRAS mutations, alcohol consumption and tobacco smoking effects on esophageal squamous-cell carcinoma carcinogenesis. Int J Biol Markers, 27:1-12.
19.
RoshandelG, SemnaniS, MalekzadehR, et al. (2012) Polycyclic aromatic hydrocarbons and esophageal squamous cell carcinoma. Arch Iran Med, 15:713-722.
20.
ShenF, ChenJ, GuoS, et al. (2016) Genetic variants in miR-196a2 and miR-499 are associated with susceptibility to esophageal squamous cell carcinoma in Chinese Han population. Tumour Biol, 37:4777-4784.
21.
SoysalS, ObermannEC, GaoF, et al. (2013) PTP1B expression is an independent positive prognostic factor in human breast cancer. Breast Cancer Res Treat, 137:637-644.
22.
St-GermainJR, TaylorP, ZhangW, et al. (2015) Differential regulation of FGFR3 by PTPN1 and PTPN2. Proteomics, 15:419-433.
23.
SuH, HuN, YangHH, et al. (2011) Global gene expression profiling and validation in esophageal squamous cell carcinoma and its association with clinical phenotypes. Clin Cancer Res, 17:2955-2966.
24.
SunX, ChenW, ChenZ, et al. (2010) Population-based case-control study on risk factors for esophageal cancer in five high-risk areas in China. Asian Pac J Cancer Prev, 11:1631-1636.
25.
TalsmaK, van HagenP, GrotenhuisBA, et al. (2012) Comparison of the 6th and 7th Editions of the UICC-AJCC TNM Classification for esophageal cancer. Ann Surg Oncol, 19:2142-2148.
26.
WangJ, LiuB, ChenX, et al. (2012) PTP1B expression contributes to gastric cancer progression. Med Oncol, 29:948-956.
27.
WangXM, ShangL, ZhangY, et al. (2013) PTP1B contributes to calreticulin-induced metastatic phenotypes in esophageal squamous cell carcinoma. Mol Cancer Res, 11:986-994.
28.
YaoY, ShaoJ, WuJ, et al. (2015) The functional variant in the 3'UTR of PTPRT with the risk of esophageal squamous cell carcinoma in a Chinese population. Cell Physiol Biochem, 36:306-314.
29.
ZhouX, XuW, ChenJ (2011) The 981C>T polymorphism in protein tyrosine phosphatase 1B is associated with decreased risk of coronary artery disease in Chinese Han population. Atherosclerosis, 218:147-150.
30.
ZhuS, BjorgeJD, FujitaDJ (2007) PTP1B contributes to the oncogenic properties of colon cancer cells through Src activation. Cancer Res, 67:10129-10137.
