Restricted accessResearch articleFirst published online 2011-10
Lack of Association Between Polymorphism −592A/C in the Promoter Region of the IL10 Gene and Tourette's Syndrome in a Family-Based Association Study in the Chinese Han Population
We evaluated the genetic contribution of the IL10−592A/C polymorphism in 108 trios with Tourette's syndrome (TS) including all their parents in a Chinese Han population by using the transmission disequilibrium test and haplotype relative risk design; no evidence for association or linkage disequilibrium was found between IL10−592A/C polymorphism and TS. These results suggested that IL10 may not play a major role in the development of TS in the Chinese Han population.
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