YuYJ, ZhangY, KenrickM, et al.Boosting brain uptake of a therapeutic antibody by reducing its affinity for a transcytosis target. Sci Transl Med, 2011; 3(84):84ra44; doi: 10.1126/scitranslmed.3002230
2.
CouchJA, YuYJ, ZhangY, et al.Addressing Safety Liabilities of TfR Bispecific Antibodies That Cross the Blood–Brain Barrier. Sci Transl Med, 2013; 5(183):183ra57; doi: 10.1126/scitranslmed.3005338
3.
KariolisMS, WellsRC, GetzJA, et al.Brain delivery of therapeutic proteins using an Fc fragment blood–brain barrier transport vehicle in mice and monkeys. Sci Transl Med, 2020; 12(545):eaay1359; doi: 10.1126/scitranslmed.aay1359
4.
UllmanJC, ArguelloA, GetzJA, et al.Brain delivery and activity of a lysosomal enzyme using a blood–brain barrier transport vehicle in mice. Sci Transl Med, 2020; 12(545):eaay1363; doi: 10.1126/scitranslmed.aay1163
5.
BarkerSJ, ThayerMB, KimC, et al.Targeting the transferrin receptor to transport antisense oligonucleotides across the mammalian blood-brain barrier. Sci Transl Med, 2024; 16(760):760; doi: 10.1126/scitranslmed.adi2245