Lopez-OtinC, BlascoMA, PartridgeL, et al.The hallmarks of aging. Cell, 2013; 153(6):1194–1217; doi: 10.1016/j.cell.2013.05.039
2.
MelzerD, PillingLC, FerrucciL. The genetics of human ageing. Nat Rev Genet, 2020; 21(2):88–101; doi: 10.1038/s41576-019-0183-6
3.
Lopez-OtinC, BlascoMA, PartridgeL, et al.Hallmarks of aging: An expanding universe. Cell, 2023; 186(2):243–278; doi: 10.1016/j.cell.2022.11.001
4.
ZadoorianA, DuX, YangH. Lipid droplet biogenesis and functions in health and disease. Nat Rev Endocrinol, 2023; 1–17; doi: 10.1038/s41574-023-00845-0
5.
IoannouMS, JacksonJ, SheuSH, et al.Neuron-astrocyte metabolic coupling protects against activity-induced fatty acid toxicity. Cell, 2019; 177(6):1522.e14–1535.e14; doi: 10.1016/j.cell.2019.04.001
6.
LiuL, MacKenzieKR, PutluriN, et al.The glia-neuron lactate shuttle and elevated ROS promote lipid synthesis in neurons and lipid droplet accumulation in glia via APOE/D. Cell Metab, 2017; 26(5):719.e6–737.e6; doi: 10.1016/j.cmet.2017.08.024
7.
YamazakiY, ZhaoN, CaulfieldTR, et al.Apolipoprotein E and Alzheimer disease: Pathobiology and targeting strategies. Nat Rev Neurol, 2019; 15(9):501–518; doi: 10.1038/s41582-019-0228-7
8.
FanningS, HaqueA, ImberdisT, et al.Lipidomic analysis of alpha-synuclein neurotoxicity identifies stearoyl CoA desaturase as a target for Parkinson treatment. Mol Cell, 2019; 73(5):1001.e8–1014.e8; doi: 10.1016/j.molcel.2018.11.028
9.
MoultonMJ, BarishS, RalhanI, et al.Neuronal ROS-induced glial lipid droplet formation is altered by loss of Alzheimer's disease-associated genes. Proc Natl Acad Sci U S A, 2021; 118(52); doi: 10.1073/pnas.2112095118
10.
ShiL, LiuX, ShiL, et al.Mid-infrared metabolic imaging with vibrational probes. Nat Methods, 2020; 17(8):844–851; doi: 10.1038/s41592-020-0883-z
11.
PapsdorfK, MiklasJW, HosseiniA, et al.Lipid droplets and peroxisomes are co-regulated to drive lifespan extension in response to mono-unsaturated fatty acids. Nat Cell Biol, 2023; 25(5):672–684; doi: 10.1038/s41556-023-01136-6
12.
ShiL, ZhengC, ShenY, et al.Optical imaging of metabolic dynamics in animals. Nat Commun, 2018; 9(1):2995; doi: 10.1038/s41467-018-05401-3
13.
LiY, ChangP, SankaranS, et al.Bioorthogonal stimulated Raman scattering imaging uncovers lipid metabolic dynamics in drosophila brain during aging. GEN Biotechnol, 2023; 2(3):247–261; doi: 10.1089/genbio.2023.0017
14.
GordonT, KannelWB, HjortlandMC, et al.Menopause and coronary heart disease. The Framingham study. Ann Intern Med, 1978; 89(2):157–161; doi: 10.7326/0003-4819-89-2-157
15.
GhaffariS, Naderi NabiF, SugiyamaMG, et al.Estrogen inhibits LDL (low-density lipoprotein) transcytosis by human coronary artery endothelial cells via GPER (G-protein-coupled estrogen receptor) and SR-BI (scavenger receptor class B type 1). Arterioscler Thromb Vasc Biol, 2018; 38(10):2283–2294; doi: 10.1161/ATVBAHA.118.310792
16.
HerkerE, VieyresG, BellerM, et al.Lipid droplet contact sites in health and disease. Trends Cell Biol, 2021; 31(5):345–358; doi: 10.1016/j.tcb.2021.01.004
SongJ, MizrakA, LeeCW, et al.Identification of two pathways mediating protein targeting from ER to lipid droplets. Nat Cell Biol, 2022; 24(9):1364–1377; doi: 10.1038/s41556-022-00974-0
19.
DenisI, PotierB, HeberdenC, et al.Omega-3 polyunsaturated fatty acids and brain aging. Curr Opin Clin Nutr Metab Care, 2015; 18(2):139–146; doi: 10.1097/MCO.0000000000000141
