PapesF, CamargoAP, de SouzaJS, et al.Transcription factor 4 loss-of-function is associated with deficit in progenitor proliferation and cortical neuron content. Nat Commun, 2022; 13(1):2387; doi: 10.1038/s41467-022-29942-w.
2.
Bioverativ. Proof-of-concept study for BIVV020 in chronic inflammatory demyelinating polyneuropathy (CIDP). Clinical Trial: NCT04658472. Available at https://clinicaltrials.gov/ct2/show/NCT04658472
PietrobonA, Yockell-LelievreJ, FloodTA, et al.Renal organoid modeling of tuberous sclerosis complex reveals lesion features arise from diverse developmental processes. Cell Rep, 2022; 40(1):111048; doi: 10.1016/j.celrep.2022.111048.
6.
Westerling-BuiA, FastEM, SoareTW, et al.Transplanted organoids empower human preclinical assessment of drug candidate for the clinic. Sci Adv, 2022; 8:eabj5633; doi: 10.1126/sciadv.abj5633.
7.
RumseyJW, LoranceC, JacksonC, et al.Classical complement pathway inhibition in a “Human-On-A-Chip” model of autoimmune demyelinating neuropathies. Adv Ther, 2022; 5(6); doi: 10.1002/adtp.202200030.
8.
EwartL, ApostolouA, BriggsS, et al.Qualifying a human liver chip for predictive toxicology: Performance assessment and economic implications. bioRxiv, 2021; doi: 10.1101/2021.12.14.472674v3.
IngberDE. Human organs-on-chips for disease modeling, drug development and personalized medicine. Nat Rev Genet, 2022; 23;467–491. doi: 10.1038/s41576-022-00466-9.
11.
ForsytheS, EraliR, SasikumarS, et al.Organoid platform in preclinical investigation of personalized immunotherapy efficacy in appendiceal cancer: Feasibility study. Clin Cancer Res, 2021; 27:5141–5150; doi: 10.1158/1078-0432.CCR-21-0982.
12.
AhnSI, SieYJ, ParkH-J, et al.Microengineereed human blood-barrier platform for understanding nanoparticle transport mechanisms. Nat Commun, 2020; 11(1):175; doi: 10.1038/s41467-019-13896-7.
13.
GurumurthyRK, KostrS, KumarN, et al.Patient-derived and mouse endo-ectocervical organoid generation, genetic manipulation and applications to model infection. Nat Protoc, 2022; 17(7):1658–1690; doi: 10.1038/s41596-022-00695-6.
14.
WatanabeS, KobayshiS, OgasawaraN, et al.Transplantation of intestinal organoids into a mouse model of colitis. Nat Protoc, 2022; 17(3):649–671; doi: 10.1038/s41596-021-00658-3.
15.
MithalA, HumeAJ, Lindstrom-VautrimJ, et al.Human pluripotent stem cell-derived intestinal organoids model SARS-CoV-2 infection revealing a common epithelial inflammatory response. Stem Cell Reports, 2021; 16(4):940–953; doi: 10.1016/j.stemcr.2021.02.019.
16.
TiwariSK, WangS, SmithD, et al.Revealing tissue-specific SARS-CoV-2 infection and host responses using human stem cell-derived lung and cerebral organoids. Stem Cell Reports, 2021; 16(3):437–445; doi: 10.1038/s41596-022-00695-6.
17.
RajanA, WeaverAM, AloisioGM, et al. The human nose organoid respiratory virus model: An ex vivo human challenge model to study respiratory syncytial virus (RS) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogenesis and evaluate therapeutics. mBio, 2022; 13(1):e0351121; doi: 10.1128/mbio.03511-21.