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References
1.
Lipinski
C
,
Hopkins
AL
Navigating chemical space for biology and medicine . Nature . 2004 ; 432 :855 –861 . DOI: 10.1038/nature03193.
2.
Hopkins
AL
,
Groom
CR
The druggable genome . Nat Rev Drug Discov . 2002 ; 1 :727 –730 . DOI: 10.1038/nrd892.
3.
Besnard
J
,
Ruda
GF
,
Setola
V
et al. Automated design of ligands to polypharmacological profiles . Nature . 2012 ; 492 :215 –220 . DOI: 10.1038/nature11691.