PollockJ. et al., Fed-batch and perfusion culture processes: economic, environmental, and operational feasibility under uncertainty, Biotechnol. Bioeng., 110, 206–219 (2013).
2.
PollockJ. et al., Optimising the design and operation of semi-continuous affinity chromatography for clinical and commercial manufacture, J. Chromatogr., A 1284, 17–27 (2013).
3.
WaltherJ. et al., The business impact of an integrated continuous biomanufacturing platform for recombinant protein production, J. Biotechnol., 213, 3–12 (2015).
4.
GE Healthcare, Application Note, “One-Step Seed Culture Expansion from One Vial of High-Density Cell Bank to 2000 L Production Bioreactor,” 29160932, Edition AB (2016).
5.
YangW. C. et al.Perfusion seed cultures improve biopharmaceutical fed-batch production capacity and product quality. Biotechnol. Prog., 30(3), 616–625 (2014).
6.
WaltherJ. et al., Perfusion Cell Culture Decreases Process and Product Heterogeneity in a Head-to-Head Comparison with Fed-Batch, J. Biotechnol., doi.org/10.1002/biot.201700733 (2018).