Abstract
A patient with severe hemophilia Type A (<1% Factor VIII) and thrombocytopenia, chronic active hepatitis, and HIV-positive serology was treated for kidney stones with percutaneous nephrolithotomy (PCNL). Platelets and Factor VIII replacement therapy were administered preoperatively, but bleeding occurred during creation of the nephrostomy tract and obscured the collecting system. The PCNL was therefore done as a second procedure after maturation of the tract, after which the patient was endoscopically free of all stones. We believe this is the first reported case of PCNL in a patient with severe hemophilia.
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