van den BergheG, WoutersP, WeekersF, VerwaestC, BruyninckxF, SchetzM, VlasselaersD, FerdinandeP, LauwersP, BouillonR. Intensive insulin therapy in the critically ill patients. N Engl J Med, 2001; 345:1359–1367.
2.
ArabiYM, DabbaghOC, TamimHM, Al-ShimemeriAA, MemishZA, HaddadSH, SyedSJ, GiridharHR, RishuAH, Al-DakerMO, KahoulSH, BrittsRJ, SakkijhaMH. Intensive versus conventional insulin therapy: a randomized controlled trial in medical and surgical critically ill patients. Crit Care Med, 2008; 36:3190–3197.
3.
BrunkhorstFM, EngelC, BloosF, Meier-HellmannA, RagallerM, WeilerN, MoererO, GruendlingM, OppertM, GrondS, OlthoffD, JaschinskiU, JohnS, RossaintR, WelteT, SchaeferM, KernP, KuhntE, KiehntopfM, HartogC, NatansonC, LoefflerM, ReinhartK. Intensive insulin therapy and pentastarch resuscitation in severe sepsis. N Engl J Med, 2008; 358:125–139.
4.
De La RosaGC, DonadoJH, RestrepoAH, QuinteroAM, GonzalezLG, SaldarriagaNE, BedoyaM, ToroJM, VelasquezJB, ValenciaJC, ArangoCM, AlemanPH, VasquezEM, ChavarriagaJC, YepesA, PulidoW, CadavidCA. Strict glycaemic control in patients hospitalised in a mixed medical and surgical intensive care unit: a randomised clinical trial. Crit Care, 2008; 12:R120.
5.
PreiserJC, DevosP, Ruiz-SantanaS, MelotC, AnnaneD, GroeneveldJ, IapichinoG, LeverveX, NitenbergG, SingerP, WernermanJ, JoannidisM, StecherA, ChioleroR. A prospective randomised multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the Glucontrol study. Intensive Care Med, 2009; 35:1738–1748.
6.
AzevedoJR, LimaER, CossettiRJ, AzevedoRP. Intensive insulin therapy versus conventional glycemic control in patients with acute neurological injury: a prospective controlled trial. Arq Neuropsiquiatr, 2007; 65:733–738.
7.
BrunoA, KentTA, CoullBM, ShankarRR, SahaC, BeckerKJ, KisselaBM, WilliamsLS. Treatment of Hyperglycemia in Ischemic Stroke (THIS): a randomized pilot trial. Stroke, 2008; 39:384–389.
8.
CheungNW, WongVW, McLeanM. The Hyperglycemia: Intensive Insulin Infusion in Infarction (HI-5) study: a randomized controlled trial of insulin infusion therapy for myocardial infarction. Diabetes Care, 2006; 29:765–770.
9.
OksanenT, SkrifvarsMB, VarpulaT, KuitunenA, PettilaV, NurmiJ, CastrenM. Strict versus moderate glucose control after resuscitation from ventricular fibrillation. Intensive Care Med, 2007; 33:2093–2100.
10.
FinferS, ChittockDR, SuSY, BlairD, FosterD, DhingraV, BellomoR, CookD, DodekP, HendersonWR, HebertPC, HeritierS, HeylandDK, McArthurC, McDonaldE, MitchellI, MyburghJA, NortonR, PotterJ, RobinsonBG, RoncoJJ. Intensive versus conventional glucose control in critically ill patients. N Engl J Med, 2009; 360:1283–1297.
11.
SiegelaarSE, HermanidesJ, Oudemans-van StraatenHM, van der VoortPH, BosmanRJ, ZandstraDF, DevriesJH. Mean glucose during ICU admission is related to mortality by a U-shaped curve in surgical and medical patients: a retrospective cohort study. Crit Care, 2010; 14:R224.
12.
van den BergheG, WilmerA, HermansG, MeerssemanW, WoutersPJ, MilantsI, VanWE, BobbaersH, BouillonR. Intensive insulin therapy in the medical ICU. N Engl J Med, 2006; 354:449–461.
13.
van den BergheG, WilmerA, MilantsI, WoutersPJ, BouckaertB, BruyninckxF, BouillonR, SchetzM. Intensive insulin therapy in mixed medical/surgical intensive care units: benefit versus harm. Diabetes, 2006; 55:3151–3159.
14.
van den BergheG, SchetzM, VlasselaersD, HermansG, WilmerA, BouillonR, MesottenD. Clinical review: Intensive insulin therapy in critically ill patients: NICE-SUGAR or Leuven blood glucose target?J Clin Endocrinol Metab, 2009; 94:3163–3170.
15.
MarikPE, PreiserJC. Toward understanding tight glycemic control in the ICU: a systematic review and metaanalysis. Chest, 2010; 137:544–551.
16.
CasaerMP, MesottenD, HermansG, WoutersPJ, SchetzM, MeyfroidtG, VanCS, IngelsC, MeerssemanP, MullerJ, VlasselaersD, DebaveyeY, DesmetL, DuboisJ, VanAA, VanderheydenS, WilmerA, van den BergheG. Early versus late parenteral nutrition in critically ill adults. N Engl J Med, 2011; 365:506–517.
17.
HermanidesJ, BosmanRJ, VriesendorpTM, DotschR, RosendaalFR, ZandstraDF, HoekstraJB, DevriesJH. Hypoglycemia is associated with intensive care unit mortality. Crit Care Med, 2010; 38:1430–1434.
18.
QaseemA, HumphreyLL, ChouR, SnowV, ShekelleP. Use of intensive insulin therapy for the management of glycemic control in hospitalized patients: a clinical practice guideline from the American College of Physicians. Ann Intern Med, 2011; 154:260–267.
19.
MoghissiES, KorytkowskiMT, DiNardoM, EinhornD, HellmanR, HirschIB, InzucchiSE, Ismail-BeigiF, KirkmanMS, UmpierrezGE. American Association of Clinical Endocrinologists and American Diabetes Association consensus statement on inpatient glycemic control. Diabetes Care, 2009; 32:1119–1131.
20.
IoannidisJP. Contradicted and initially stronger effects in highly cited clinical research. JAMA, 2005; 294:218–228.
21.
Sodi-PallaresD, TestelliMR, FishlederBL, BisteniA, MedranoGA, FriedlandC, De MicheliA. Effects of an intravenous infusion of a potassium-glucose-insulin solution on the electrocardiographic signs of myocardial infarction. A preliminary clinical report. Am J Cardiol, 1962; 9:166–181.
22.
MehtaSR, YusufS, DiazR, ZhuJ, PaisP, XavierD, PaolassoE, AhmedR, XieC, KazmiK, TaiJ, OrlandiniA, PogueJ, LiuL. Effect of glucose-insulin-potassium infusion on mortality in patients with acute ST-segment elevation myocardial infarction: the CREATE-ECLA randomized controlled trial. JAMA, 2005; 293:437–446.
23.
PuskarichMA, RunyonMS, TrzeciakS, KlineJA, JonesAE. Effect of glucose-insulin-potassium infusion on mortality in critical care settings: a systematic review and meta-analysis. J Clin Pharmacol, 2009; 49:758–767.
24.
MalmbergK, RydenL, EfendicS, HerlitzJ, NicolP, WaldenstromA, WedelH, WelinL. Randomized trial of insulin-glucose infusion followed by subcutaneous insulin treatment in diabetic patients with acute myocardial infarction (DIGAMI study): effects on mortality at 1 year. J Am Coll Cardiol, 1995; 26:57–65.
25.
MalmbergK, RydenL, WedelH, BirkelandK, BootsmaA, DicksteinK, EfendicS, FisherM, HamstenA, HerlitzJ, HildebrandtP, MacLeodK, LaaksoM, Torp-PedersenC, WaldenstromA. Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity. Eur Heart J, 2005; 26:650–661.
26.
WrightRS, AndersonJL, AdamsCD, BridgesCR, CaseyDEJr., EttingerSM, FesmireFM, GaniatsTG, JneidH, LincoffAM, PetersonED, PhilippidesGJ, TherouxP, WengerNK, ZidarJP, AndersonJL, AdamsCD, AntmanEM, BridgesCR, CaliffRM, CaseyDEJr, ChaveyWE, FesmireFM, HochmanJS, LevinTN, LincoffAM, PetersonED, TherouxP, WengerNK, WrightRS. 2011 ACCF/AHA focused update incorporated into the ACC/AHA 2007 Guidelines for the Management of Patients with Unstable Angina/Non-ST-Elevation Myocardial Infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines developed in collaboration with the American Academy of Family Physicians, Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons. J Am Coll Cardiol, 2011; 57:e215–e367.
27.
VenkitachalamL, RileyK, LipskaK, InzucchiSE, GoyalA, SpertusJA, MasoudiFA, JonesPG, KosiborodM. Temporal trends in the managment of severe hyperglycemia among patients hospitalized with acute myocardial infarction. J Am Coll Cardiol, 2010; 55,10A:A143.E1339.
28.
UmpierrezGE, SmileyD, JacobsS, PengL, TemponiA, MulliganP, UmpierrezD, NewtonC, OlsonD, RizzoM. Randomized study of basal-bolus insulin therapy in the inpatient management of patients with type 2 diabetes undergoing general surgery (RABBIT 2 Surgery)Diabetes Care, 2011; 34:256–261.
