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References
1.ENCODE Project Consortium . An integrated encyclopedia of DNA elements in the human genome . Nature . 2012 ; 489 :57 –74 .
2.
Urnov
FD
,
Rebar
EJ
,
Holmes
MC
, et al. Genome editing with engineered zinc finger nucleases . Nat Rev Genet . 2010 ; 11 :636 –646 .
3.
Gaj
T
,
Gersbach
CA
,
Barbas
CF
. ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering . Trends Biotechnol . 2013 ; 31 :397 –405 .
4.
Carroll
D
. Genome engineering with targetable nucleases . Annu Rev Biochem . 2014 ; 83 :409 –439 .
5.
Doudna
JA
,
Charpentier
E
. The new frontier of genome engineering with CRISPR-Cas9 . Science . 2014 ; 346 :1258096 .
6.
Hsu
PD
,
Lander
ES
,
Zhang
F
. Development and applications of CRISPR-Cas9 for genome engineering . Cell . 2014 ; 157 :1262 –1278 .
7.
Kim
H
,
Kim
J-S
. A guide to genome engineering with programmable nucleases . Nat Rev Genet . 2014 ; 15 :321 –334 .
8.
Chylinski
K
,
Makarova
KS
,
Charpentier
E
, et al. Classification and evolution of type II CRISPR-Cas systems . Nucleic Acids Res . 2014 ; 42 :6091 –6105 .
9.
Barrangou
R
,
Doudna
JA
. Applications of CRISPR technologies in research and beyond . Nat Biotechnol . 2016 ; 34 :933 –941 .
10.
Wang
H
,
La Russa
M
,
Qi
LS
. CRISPR/Cas9 in genome editing and beyond . Annu Rev Biochem . 2016 ; 85 :227 –264 .
11.
Tsherniak
A
,
Vazquez
F
,
Montgomery
PG
, et al. Defining a cancer dependency map . Cell . 2017 ; 170 :564 –576 .e16.
12.
Bailey
AL
,
Diamond
MS
. A Crisp(r) new perspective on SARS-CoV-2 biology . Cell . 2021 ; 184 :15 –17 .
13.
Jasin
M
,
Haber
JE
. The democratization of gene editing: Insights from site-specific cleavage and double-strand break repair . DNA Repair . 2016 ; 44 :6 –16 .
14.
Yeh
CD
,
Richardson
CD
,
Corn
JE
. Advances in genome editing through control of DNA repair pathways . Nat Cell Biol . 2019 ; 21 :1468 –1478 .
15.
Maizels
N
,
Davis
L
. Initiation of homologous recombination at DNA nicks . Nucleic Acids Res . 2018 ; 46 :6962 –6973 .
16.
Anzalone
AV
,
Randolph
PB
,
Davis
JR
, et al. Search-and-replace genome editing without double-strand breaks or donor DNA . Nature . 2019 ; 576 :149 –157 .
17.
Brosh
R
,
Laurent
JM
,
Ordoñez
R
, et al. A versatile platform for locus-scale genome rewriting and verification . Proc Natl Acad Sci . 2021 ; 118 :e2023952118 .
18.
Boeke
JD
,
Church
G
,
Hessel
A
, et al. The genome project-write . Science . 2016 ; 353 :126 –127 .
