Primary adenocarcinoma of the urethra is rarely reported. We report a case of a 47-year-old male with symptoms of urinary obstruction started 2 years before diagnosis. Video-assisted urethrocystoscopy revealed a papillary mass almost obstructing the entire lumen with bleeding. Pathology report was consistent with primary adenocarcinoma of the urethra.
Get full access to this article
View all access options for this article.
References
1.
BoorjianSA, KimSP, WeightCJ, ChevilleJC, ThapaP, FrankI. Risk factors and outcomes of urethral recurrence following radical cystectomy. Eur Urol, 2011; 60:1266–1272.
2.
MaekM. [Penis-preserving surgery in patients with primary penile urethral cancer] (Ger). Urologe A, 2014; 53:1800–1804.
3.
GattaG, van der ZwanJM, CasaliPG, et al.Rare cancers are not so rare: The rare cancer burden in Europe. Eur J Cancer, 2011; 47:2493–2511.
4.
DalbagniG, ZhangZF, LacombeL, HerrHW. Male urethral carcinoma: Analysis of treatment outcome. Urology, 1999; 53:1126–1132.
5.
RabbaniF. Prognostic factors in male urethral cancer. Cancer, 2011; 117:2426–2434.
6.
MostofiFK, DavisCJJr., SesterhennIA. Carcinoma of the male and female urethra. Urol Clin North Am, 1992; 19:347–358.
Medina PerezM, Valero PuertaJ, Sanchez GonzalezM, Valpuesta FernandezI, Marin MartinJ. [Squamous carcinoma of the male urethra, its presentation as a scrotal abscess] (Spa). Arch Esp Urol, 1999; 52:792–794.
9.
Van de VoordeW, MeertensB, BaertL, LauwerynsJ. Urethral squamous cell carcinoma associated with urethral stricture and urethroplasty. Eur J Surg Oncol, 1994; 20:478–483.
10.
ColapintoV, EvansDH. Primary carcinoma of the male urethra developing after urethroplasty for stricture. J Urology, 1977; 118:581–584.
SawczukI, AcostaR, GrantD, WhiteRD. Post urethroplasty squamous cell carcinoma. N Y State J Med, 1986; 86:261–263.
13.
MohanH, BalA, PuniaRP, BawaAS. Squamous cell carcinoma of the prostate. Int J Urol, 2003; 10:114–116.
14.
ArvaNC, DasK. Diagnostic dilemmas of squamous differentiation in prostate carcinoma case report and review of the literature. Diagn Pathol, 2011; 6:46.
15.
CuppMR, MalekRS, GoellnerJR, EspyMJ, SmithTF. Detection of human papillomavirus DNA in primary squamous cell carcinoma of the male urethra. Urology, 1996; 48:551–555.
16.
WienerJS, LiuET, WaltherPJ. Oncogenic human papillomavirus type 16 is associated with squamous cell cancer of the male urethra. Cancer Res, 1992; 52:5018–5023.
17.
GandhiJS, KhuranaA, TewariA, MehtaA. Clear cell adenocarcinoma of the male urethral tract. Indian J Pathol Microbiol, 2012; 55:245–247.
18.
VapnekJM, HricakH, CarrollPR. Recent advances in imaging studies for staging of penile and urethral carcinoma. Urol Clin North Am, 1992; 19:257–266.
19.
DerksenJW, VisserO, de la RiviereGB, MeulemanEJ, HeldewegEA, LagerveldBW. Primary urethral carcinoma in females: An epidemiologic study on demographical factors, histological types, tumour stage and survival. World J Urol, 2013; 31:147–153.
20.
GheilerEL, TefilliMV, TiguertR, de OliveiraJG, PontesJE, WoodDPJr. Management of primary urethral cancer. Urology, 1998; 52:487–493.
21.
KarnesRJ, BreauRH, LightnerDJ. Surgery for urethral cancer. Urol Clin North Am, 2010; 37:445–457.
22.
BlaivasJG, FlisserAJ, BleusteinCB, PanagopoulosG. Periurethral masses: Etiology and diagnosis in a large series of women. Obstet and Gynecol, 2004; 103(5 Pt 1):842–847.
23.
TouijerAK, DalbagniG. Role of voided urine cytology in diagnosing primary urethral carcinoma. Urology, 2004; 63:33–35.