officially retracts the paper entitled, “The Effect of PTCH1 on Ovarian Cancer Cell Proliferation and Apoptosis,” by Fang Zheng, Xinyi Xiao, and Chunmei Wang (Cancer Biother Radiopharm 2019;34:2;103–109; doi: 10.1089/cbr.2018.2626) due to the discovery that the paper was submitted from a paper mill which is a violation of the journal's proper protocols, and is considered an infraction against the rigorous standards of scientific publishing.
The Editor and Publisher of Cancer Biotherapy and Radiopharmaceuticals are committed to preserving the scientific literature and the community it serves and does not tolerate any violations of scientific misconduct.
Get full access to this article
View all access options for this article.
References
1.
ReidBM, PermuthJB, SellersTA. Epidemiology of ovarian cancer: A review. Cancer Biol Med, 2017; 14:9.
2.
EthierJL, LheureuxS, OzaAM. The role of niraparib for the treatment of ovarian cancer. Future Oncol, 2018; 14:25.
3.
WhitwellHJ, BlyussO, MenonU, et al.Parenclitic networks for predicting ovarian cancer. Oncotarget, 2018; 9:22717.
4.
SiegelRL, FedewaSA, MillerKD, et al.Cancer statistics for Hispanics/Latinos, 2015. CA Cancer J Clin, 2015; 65:457.
5.
La VecchiaC. Ovarian cancer: Epidemiology and risk factors. Eur J Cancer Prev, 2017; 26:55.
6.
FerlayJ, SoerjomataramI, DikshitR, et al.Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer, 2015; 136:E359.
7.
ChahalKK, ParleM, AbagyanR. Hedgehog pathway and smoothened inhibitors in cancer therapies. Anticancer Drugs, 2018; 29:387.
8.
XinM, JiX, De La CruzLK, et al.Strategies to target the Hedgehog signaling pathway for cancer therapy. Med Res Rev, 2018; 38:870.
9.
XuX, LuY, LiY, et al.Sonic Hedgehog signaling in thyroid cancer. Front Endocrinol, 2017; 8:284.
10.
DixitR, PandeyM, TripathiSK, et al.Comparative analysis of mutational profile of sonic hedgehog gene in gallbladder cancer. Dig Dis Sci, 2017; 62:708.
11.
MunozJL, Rodriguez-CruzV, RamkissoonSH, et al.Temozolomide resistance in glioblastoma occurs by miRNA-9-targeted PTCH1, independent of sonic hedgehog level. Oncotarget, 2015; 6:1190.
12.
YouS, ZhouJ, ChenS, et al.PTCH1, a receptor of Hedgehog signaling pathway, is correlated with metastatic potential of colorectal cancer. Upsala J Med Sci, 2010; 115:169.
13.
HabibJG, O'ShaughnessyJA. The hedgehog pathway in triple-negative breast cancer. Cancer Med, 2016; 5:2989.
14.
ZhengW, LuS, CaiH, et al.Deguelin inhibits proliferation and migration of human pancreatic cancer cells in vitro targeting hedgehog pathway. Oncol Lett, 2016; 12:2761.
15.
ChaudaryN, PintilieM, HedleyD, et al.Hedgehog inhibition enhances efficacy of radiation and cisplatin in orthotopic cervical cancer xenografts. Br J Cancer, 2017; 116:50.
16.
AkyalaAI, PeppelenboschMP. Gastric cancer and Hedgehog signaling pathway: Emerging new paradigms. Genes Cancer, 2018; 9:1.
17.
SkodaAM, SimovicD, KarinV, et al.The role of the Hedgehog signaling pathway in cancer: A comprehensive review. Bosn J Basic Med Sci, 2018; 18:8.
18.
GuD, SchlotmanKE, XieJ. Deciphering the role of hedgehog signaling in pancreatic cancer. J Biomed Res, 2016; 30:353.
19.
KerlK, MorenoN, HolstenT, et al.Arsenic trioxide inhibits tumor cell growth in malignant rhabdoid tumors in vitro and in vivo by targeting overexpressed Gli1. Int J Cancer, 2014; 135:989.
20.
WangD, KongX, LiY, et al.Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway. Biochem Biophys Res Commun, 2017; 493:521.
21.
WangF, WangW, LiJ, et al.Sulforaphane reverses gefitinib tolerance in human lung cancer cells via modulation of sonic hedgehog signaling. Oncol Lett, 2018; 15:109.
22.
WilsLJ, BijlsmaMF. Epigenetic regulation of the Hedgehog and Wnt pathways in cancer. Crit Rev Oncol/Hematol, 2018; 121:23.
23.
LiY, ZhangD, ChenC, et al.MicroRNA-212 displays tumor-promoting properties in non-small cell lung cancer cells and targets the hedgehog pathway receptor PTCH1. Mol Biol Cell, 2012; 23:1423.
24.
MauracI, SabolM, MusaniV, et al.A low-grade ovarian carcinoma case with coincident LOH of PTCH1 and BRCA1, and a mutation in BRCA1. Int J Gynecol Pathol, 2012; 31:264.
25.
BhattacharyaR, KwonJ, AliB, et al.Role of hedgehog signaling in ovarian cancer. Clin Cancer Res, 2008; 14:7659.
26.
LiaoX, SiuMK, AuCW, et al.Aberrant activation of hedgehog signaling pathway in ovarian cancers: Effect on prognosis, cell invasion and differentiation. Carcinogenesis, 2009; 30:131.
27.
BarnesEA, KongM, OllendorffV, et al.Patched1 interacts with cyclin B1 to regulate cell cycle progression. EMBO J, 2001; 20:2214.
28.
ChoiCH, RyuJY, ChoYJ, et al.The anti-cancer effects of itraconazole in epithelial ovarian cancer. Sci Rep, 2017; 7:6552.
29.
StegAD, BurkeMR, AmmHM, et al.Proteasome inhibition reverses hedgehog inhibitor and taxane resistance in ovarian cancer. Oncotarget, 2014; 5:7065.
