officially retracts the paper entitled, “miR-155 Affects Osteosarcoma MG-63 Cell Autophagy Induced by Adriamycin Through Regulating PTEN-I3K/AKT/mTOR Signaling Pathway” by Lin Wang, Bing Tang, Heng Han, Dan Mao, Jie Chen, Yun Zeng, and Min Xiong (Cancer Biother Radiopharm 2018;33(1):32–38; doi: 10.1089/cbr.2017.2306) due to the discovery that the paper was submitted from a paper mill, which is a violation of the journal's standard protocols.
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References
1.
YangJZ, MaSR, RongXL, et al.Characterization of multidrugresistant osteosarcoma sublines and the molecular mechanisms of resistance. Mol Med Rep, 2016; 14:3269.
2.
DuMD, HeKY, QinG, et al.Adriamycin resistance-associated prohibitin gene inhibits proliferation of human osteosarcoma MG63 cells by interacting with oncogenes and tumor suppressor genes. Oncol Lett, 2016; 12:1994.
3.
O'FarrillJS, GordonN. Autophagy in osteosarcoma. Adv Exp Med Biol, 2014; 804:147.
4.
HeC, DongX, ZhaiB, et al.MiR-21 mediates sorafenib resistance of hepatocellular carcinoma cells by inhibiting autophagy via the PTEN/Akt pathway. Oncotarget, 2015; 6:28867.
5.
SuR, JinX, ZhangW, et al.Particulate matter exposure induces the autophagy of macrophages via oxidative stress-mediated PI3K/AKT/mTOR pathway. Chemosphere, 2017; 167:444.
6.
LiY, LiuY, ShiF, et al. Knockdown of Rap1b enhances apoptosis and autophagy in gastric cancer cells via the PI3K/Akt/mTOR pathway. Oncol Res 2016;24: 287.
7.
GuoY, ChangH, LiJ, et al.Thymosin alpha 1 suppresses proliferation and induces apoptosis in breast cancer cells through PTEN-mediated inhibition of PI3K/Akt/mTOR signaling pathway. Apoptosis, 2015; 20:1109.
8.
TrigkaEA, LevidouG, SaettaAA, et al.A detailed immunohistochemical analysis of the PI3K/AKT/mTOR pathway in lung cancer: Correlation with PIK3CA, AKT1, K-RAS or PTEN mutational status and clinicopathological features. Oncol Rep, 2013; 30:623.
9.
TalesaVN, FerriI, BellezzaG, et al.Glyoxalase 2 is involved in human prostate cancer progression as part of a mechanism driven by PTEN/PI3K/AKT/mTOR signaling with involvement of PKM2 and ERalpha. Prostate, 2017; 77:196.
10.
YangX, ChengY, LiP, et al.A lentiviral sponge for miRNA-21 diminishes aerobic glycolysis in bladder cancer T24 cells via the PTEN/PI3K/AKT/mTOR axis. Tumour Biol, 2015; 36:383.
11.
SunX, GengX, ZhangJ, et al.miR-155 promotes the growth of osteosarcoma in a HBP1-dependent mechanism. Mol Cell Biochem, 2015; 403:139.
12.
ZhaoQ, WangZ, WuL, et al.Aspirin may inhibit angiogenesis and induce autophagy by inhibiting mTOR signaling pathway in murine hepatocarcinoma and sarcoma models. Oncol Lett, 2016; 12:2804.
13.
RohatgiRA, ShawLM. An autophagy-independent function for Beclin 1 in cancer. Mol Cell Oncol 2016;3. pii: e1030539.
14.
CaoC, SubhawongT, AlbertJM, et al.Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells. Cancer Res, 2006; 66:10040.
15.
KimEJ, JeongJH, BaeS, et al.mTOR inhibitors radiosensitize PTEN-deficient non-small-cell lung cancer cells harboring an EGFR activating mutation by inducing autophagy. J Cell Biochem, 2013; 114:1248.
16.
RoblB, PauliC, BotterSM, et al.Prognostic value of tumor suppressors in osteosarcoma before and after neoadjuvant chemotherapy. BMC Cancer, 2015; 15:379.
17.
ZhaoG, CaiC, YangT, et al.MicroRNA-221 induces cell survival and cisplatin resistance through PI3K/Akt pathway in human osteosarcoma. PLoS One, 2013; 8:e53906.
18.
Diaz-MonteroCM, WygantJN, McIntyreBW. PI3-K/Akt-mediated anoikis resistance of human osteosarcoma cells requires Src activation. Eur J Cancer, 2006; 42:1491.
19.
ChenL, JiangK, JiangH, et al.miR-155 mediates drug resistance in osteosarcoma cells via inducing autophagy. Exp Ther Med, 2014; 8:527.
20.
LvL, AnX, LiH, et al.Effect of miR-155 knockdown on the reversal of doxorubicin resistance in human lung cancer A549/dox cells. Oncol Lett, 2016; 11:1161.
21.
YuDD, LvMM, ChenWX, et al.Role of miR-155 in drug resistance of breast cancer. Tumour Biol, 2015; 36:1395.
22.
ShenR, WangY, WangCX, et al.MiRNA-155 mediates TAM resistance by modulating SOCS6-STAT3 signalling pathway in breast cancer. Am J Transl Res, 2015; 7:2115.
23.
NingL, Guo-ChunZ, Sheng-LiA, et al.Inhibition of autophagy induced by PTEN loss promotes intrinsic breast cancer resistance to trastuzumab therapy. Tumour Biol, 2016; 37:5445.
