AckermanDL, GreenlandS, BystritskyA: Clinical characteristics of response to fluoxetine treatment of obsessive-compulsive disorder. J Clin Psychopharmacol, 18:185–192, 1998.
3.
American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 4th ed. Washington, DC: American Psychiatric Association; 1994.
4.
American Psychiatric Association: DSM-5 Task Force. In: Diagnostic and Statistical Manual of Mental Disorders. Washington, DC: American Psychiatric Association; 2013.
5.
ApterA, FallonTJJr, KingRA, RatzoniG, ZoharAH, BinderM, WeizmanA, LeckmanJF, PaulsDL, KronS, CohenDJ: Obsessive-compulsive characteristics: From symptoms to syndrome. J Am Acad Child Adolesc Psychiatry, 35:907–912, 1996.
6.
Arrojo–RomeroM, Tajes AlonsoM, de LeonJ: Lamotrigine augmentation of serotonin reuptake inhibitors in severe and long-term treatment-resistant obsessive-compulsive disorder. Case Rep Psychiatry, 2013:612459, 2013.
7.
BisolLW, LaraDR: Improvement of obsessive-compulsive disorder with divalproex and lamotrigine in two patients with bipolar II disorder. Pharmacopsychiatry, 42:37–39, 2009.
8.
BlochMH, Landeros–WeisenbergerA, KelmendiB, CoricV, BrackenMB, LeckmanJF: A systematic review: Antipsychotic augmentation with treatment refractory obsessive-compulsive disorder. Mol Psychiatry, 11:622–632, 2006.
9.
BrunoA, MicoU, PandolfoG, MallamaceD, AbenavoliE, Di NardoF, D'ArrigoC, SpinaE, ZoccaliRA, MuscatelloMR: Lamotrigine augmentation of serotonin reuptake inhibitors in treatment-resistant obsessive-compulsive disorder: A double-blind, placebo-controlled study. J Psychopharmacol, 26:1456–1462, 2012.
GrantP, LougeeL, HirschtrittM, SwedoSE: An open-label trial of riluzole, a glutamate antagonist, in children with treatment-resistant obsessive-compulsive disorder. J Child Adolesc Psychopharmacol, 17:761–767, 2007.
15.
HaghighiM, JahangardL, Mohammad–BeigiH, BajoghliH, HafezianH, RahimiA, AfsharH, Holsboer–TrachslerE, BrandS: In a double-blind, randomized and placebo-controlled trial, adjuvant memantine improved symptoms in inpatients suffering from refractory obsessive-compulsive disorders (OCD). Psychopharmacology (Berl), 228:633–640, 2013.
16.
HurleySC: Lamotrigine update and its use in mood disorders. Ann Pharmacother, 36:860–873, 2002.
17.
KesslerRC, BerglundP, DemlerO, JinR, MerikangasKR, WaltersEE: Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry, 62:593–602, 2005.
18.
KumarTC, KhannaS: Lamotrigine augmentation of serotonin re-uptake inhibitors in obsessive-compulsive disorder. Aust N Z J Psychiatry, 34:527–528, 2000.
LeonardHL: New developments in the treatment of obsessive–compulsive disorder. J Clin Psychiatry, 58Suppl 14:39–45, 1997.
21.
MowlaA, KhajeianAM, SahraianA, ChohedriAH, KashkoliF: Topiramate augmentation in resistant OCD: A double-blind placebo-controlled clinical trial. CNS Spectr, 15: 613–617, 2010.
22.
National Institute for Health and Clinical Excellence. NICE Obsessive-compulsive disorder: quick reference guide. 2005. Available at guidence.nice.org.uk/CG31/QuickRefGuide/pdf/English.
23.
PallantiS, BernardiS, AntoniniS, SinghN, HollanderE: Ondansetron augmentation in treatment-resistant obsessive-compulsive disorder: A preliminary, single-blind, prospective study. CNS Drugs, 23:1047–1055, 2009.
SeoHJ, ChiesaA, LeeSJ, PatkarAA, HanC, MasandPS, SerrettiA, PaeCU: Safety and tolerability of lamotrigine: results from 12 placebo-controlled clinical trials and clinical implications. Clin Neuropharmacol, 34:39–47, 2011.
30.
SerataD, KotzalidisGD, RapinesiC, JaniriD, Di PietroS, CalloviniG, PiacentinoD, GasperoniC, BrugnoliR, FerriVR, GirardiN, TatarelliR, FerracutiS, AngelettiG, GirardiP, Del CasaleA: Are 5-HT antagonists effective in obsessive-compulsive disorder? A systematic review of literature. Hum Psychopharmacol, 30:70–84, 2015.
31.
SimpsonHB, FoaEB, LiebowitzMR, LedleyDR, HuppertJD, CahillS, VermesD, SchmidtAB, HembreeE, FranklinM, CampeasR, HahnCG, PetkovaE: A randomized, controlled trial of cognitive-behavioral therapy for augmenting pharmacotherapy in obsessive-compulsive disorder. Am J Psychiatry, 165:621–630, 2008.
32.
SoltaniF, SayyahM, FeizyF, MalayeriA, SiahpooshA, MotlaghI: A double-blind, placebo-controlled pilot study of ondansetron for patients with obsessive-compulsive disorder. Hum Psychopharmacol, 25:509–513, 2010.
33.
SteinDJ, KoenN, FinebergN, FontenelleLF, MatsunagaH, OsserD, SimpsonHB: A 2012 evidence-based algorithm for the pharmacotherapy for obsessive-compulsive disorder. Curr Psychiatry Rep, 14:211–219, 2012.
UzunO: Lamotrigine as an augmentation agent in treatment-resistant obsessive-compulsive disorder: A case report. J Psychopharmacol, 24:425–427, 2010.
36.
van der LoosM, CalabreseJ, NolenW, MuzinaD: Pharmacological profile and clinical utility of lamotrigine in mood disorders. In: Bipolar Psychopharmacotherapy: Caring for the Patient, 2nd ed. Edited by AkiskalH., and TohenM.. Chichester: Wiley-Blackwell; 2011; pp. 45–60.
WuK, HannaGL, RosenbergDR, ArnoldPD: The role of glutamate signaling in the pathogenesis and treatment of obsessive-compulsive disorder. Pharmacol Biochem Behav, 100:726–735, 2012.