American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 4th ed. Washington, DC: American Psychiatric Association; 1994.
4.
CaponeG, GoyalP, AresW, LanniganE: Neurobehavioral disorders in children, adolescents, and young adults with Down syndrome. Am J Med Genet C Semin Med Genet, 142C:158–172, 2006.
GrantP, LougeeL, HirschtrittM, SwedoSE. An open-label trial of riluzole, a glutamate antagonist, in children with treatment-resistant obsessive-compulsive disorder. J Child Adolesc Psychopharmacol, 17:761–767, 2007.
9.
HezelDM, BeattieK, StewartSE. Memantine as an augmenting agent for severe pediatric OCD. Am J Psychiatry, 166:237, 2009.
10.
MohanM, BennettC, CarpenterPK: Memantine for dementia in people with Down syndrom. Cochrane Database of Stematic Reviews, 2009, Issue 1, Art. No: CD07657. DOI: 10.1002/14651858.CD007657.
11.
O'DwyerJ, HolmesJ, CollacottRA. Two cases of obsessive-compulsive disorder in individuals with Down's syndrome. J Nerv Ment Dis, 180:603–604, 1992.
12.
ParsonsCG, StöfflerA, DanyszW: Memantine: A NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system—too little activation is bad, too much is even worse. Neuropharmacology, 53:699–723, 2007.
Pediatric OCD Treatment Study (POTS) Team: Cognitive-behavior therapy, sertraline, and their combination for children and adolescents with obsessive-compulsive disorder: The Pediatric OCD Treatment Study (POTS) randomized controlled trial. JAMA, 292:1969–1976, 2004.
15.
PittengerC, BlochMH, WilliamsK. Glutamate abnormalities in obsessive compulsive disorder: Neurobiology, pathophysiology, and treatment. Pharmacol Ther, 132:314–332, 2011.
16.
PoyurovskyM, WeizmanR, WeizmanA, KoranL: Memantine for treatment-resistant OCD. Am J Psychiatry, 162:2191–2192, 2005.
17.
PrasherVP: Review of donepezil, rivastigmine, galantamine and memantine for the treatment of dementia in Alzheimer's disease in adults with Down syndrome: Implications for the intellectual disability population. Int J Geriatr Psychiatry, 19:509–515, 2004.
18.
PrasherVP, DayS: Brief report: obsessive-compulsive disorder in adults with Down's Syndrome. J Autism Dev Disord, 25:453–458, 1995.
19.
StewartSE, JenikeEA, HezelDM, StackDE, DodmanNH, ShusterL, JenikeMA: A single-blinded case-control study of memantine in severe obsessive-compulsive disorder. J Clin Psychopharmacol, 30:34–39, 2010.
20.
SutorB, HansenMR, BlackJL. Obsessive compulsive disorder treatment in patients with Down syndrome: a case series. Downs Syndr Res Pract, 10:1–3, 2006.
21.
WuK, HannaGL, RosenbergDR, ArnoldPD. The role of glutamate signaling in the pathogenesis and treatment of obsessive-compulsive disorder. Pharmacol Biochem Behav, 100:726–735, 2012.