Quetiapine and Clozapine Combination Treatment for Tourette's Syndrome in an Adolescent Boy: Potential Role of Dopamine Supersensitivity in Loss of Treatment Response
Restricted accessLetterFirst published online March, 2015
Quetiapine and Clozapine Combination Treatment for Tourette's Syndrome in an Adolescent Boy: Potential Role of Dopamine Supersensitivity in Loss of Treatment Response
AlhamadAM: Gilles de la Tourette syndrome treated effectively with clozapine. Neurosciences, 8:198–200, 2003.
2.
American Psychiatric Association: Diagnostic and statistical manual of mental disorders, 4th ed., Text Revision. Washington, DC: American Psychiatric Association; 2000.
3.
BastiampillaiT, DhillonR, MohindraR: Exacerbation of tics secondary to clozapine therapy. Aust N Z J Psychiatry., 42:1068–1070, 2008.
4.
BedardAM, MaheuxJ, LevesqueD and SamahaAN. Prior haloperidol, but not olanzapine, exposure augments the pursuit of reward cues: Implications for substance abuse in schizophrenia. Schizophr Bull, 39:692–702, 2013.
5.
BegumM.: Clozapine-induced stuttering, facial tics and myoclonic seizures: A case report. Aust N Z J Psychiatry
6.
Bos-VenemanNG, MinderaaRB, HoekstraPJ: The DRD4 gene and severity of tics and comorbid symptoms: main effects and interactions with delivery complications. Mov Disord, 25:1470–1476, 2010.
7.
ChenS, GongH, ChenX.: Quetiapine-related tic in a pediatric bipolar patient. J Child Adolesc Psychopharmacol
8.
HassanN, CavannaAE: The prognosis of Tourette syndrome: Implications for clinical practice. Funct Neurol, 27:23–27, 2012.
9.
KataokaY, KalanithiPS, GrantzH, SchwartzML, SaperC, LeckmanJF, VaccarinoFM: Decreased number of parvalbumin and cholinergic interneurons in the striatum of individuals with Tourette syndrome. J Comp Neurol, 518:277–291, 2010.
10.
KnightT, SteevesT, DayL, LowerisonM, JetteN, PringsheimT: Prevalence of tic disorders: A systematic review and meta-analysis. Pediatr Neurol, 47:77–90, 2012.
11.
McDougallSA, ValentineJM, GonzalezAE, HumphreyDE, WidarmaCB, CrawfordCA: Behavioral effects of dopamine receptor inactivation during the adolescent period: age-dependent changes in dorsal striatal D2 (high) receptors. Psychopharmacology, 231:1637–1647, 2014.
12.
MukaddesNM, AbaliO: Quetiapine treatment of children and adolescents with Tourette's disorder. J Child Adolesc Psychopharmacol, 13:295–299, 2003.
13.
ParragaHC, WoodwardRL: Quetiapine for Tourette's syndrome. J Am Acad Child Adolesc Psychiatry, 40:389–391, 2001.
14.
PiccinniA, VeltriA, MarazzitiD, MoroniI, Dell'OssoL.: Effectiveness of a clozapine–aripiprazole combination in Tourette syndrome and bipolar spectrum disorder. J Neuropsychiatry Clin Neurosci
15.
PringsheimT, DojaA, GormanD, McKinlayD, DayL, BillinghurstL, CarrollA, DionY, LuscombeS, SteevesT, SandorP: Canadian guidelines for the evidence-based treatment of tic disorders: pharmacotherapy. Can J Psychiatry, 57:133–143, 2012.
16.
RiemerC, BorroniE, Levet–TrafitB, MartinJR, PoliS, PorterRH, BosM: Influence of the 5-HT6 receptor on acetylcholine release in the cortex: pharmacological characterization of 4-(2-bromo-6-pyrrolidin-1-ylpyridine-4-sulfonyl)phenylamine, a potent and selective 5-HT6 receptor antagonist. J Med Chem, 46:1273–1276, 2003.
17.
RizzoR, GulisanoM: Clinical pharmacology of comorbid attention deficit hyperactivity disorder in Tourette syndrome. Int Rev Neurobiol, 112:415–444, 2013.
18.
RoessnerV, PlessenKJ, RothenbergerA, LudolphAG, RizzoR, SkovL, StrandG, SternJS, TermineC, HoekstraPJ. ESSTS Guidelines Group: European clinical guidelines for Tourette syndrome and other tic disorders. Part II: Pharmacological treatment. Eur Child Adolesc Psychiatry, 20:173–196, 2011.
19.
SamahaAN, SeemanP, StewartJ, RajabiH, KapurS: “Breakthrough” dopamine supersensitivity during ongoing antipsychotic treatment leads to treatment failure over time. J Neurosci, 27:2979–2986, 2007.
20.
SchallerJL, BeharD: Quetiapine treatment of adolescent and child tic disorders. Two case reports. Eur Child Adolesc Psychiatry, 11:196–197, 2002.
SeemanP: All roads to schizophrenia lead to dopamine supersensitivity and elevated dopamine D2(high) receptors. CNS Neurosci Ther, 17:118–132, 2011.
23.
SwainJE, ScahillL, LombrosoPJ, KingRA, LeckmanJF: Tourette syndrome and tic disorders: a decade of progress. J Am Acad Child Adolesc Psychiatry, 46:947–968, 2007.
24.
WongDF, BrasicJR, SingerHS, SchretlenDJ, KuwabaraH, ZhouY, NandiA, MarisMA, AlexanderM, YeW, RoussetO, KumarA, SzaboZ, GjeddeA, GraceAA: Mechanisms of dopaminergic and serotonergic neurotransmission in Tourette syndrome: clues from an in vivo neurochemistry study with PET. Neuropsychopharmacology, 33:1239–1251, 2008.