Guanfacine Extended Release in Two Patients with Pervasive Developmental Disorders

Aman MG . Stimulant drug effects in developmental disorders and hyperactivity toward a resolution of disparate findings. J Autism Dev Disord, 12:385–396. 1982.

American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th Text Revision (DSM-IV-TR) Washington, DC: American Psychiatric Association, 2000.

Biederman J , Melmed RD , Patel A , McBurnett K , Konow J , Lyne A , Scherer N . for the SPD503 Study Group. A randomized, double-blind, placebo-controlled study of guanfacine extended release in children and adolescents with Attention-Deficit/Hyperactivity Disorder. Pediatrics, 121:e73–e84. 2008.

Conner D , Spencer T , Kratochvil C , López FA , Lyne A , Stat C , Tremblay G . Effects of guanfacine extended release on secondary measures in children with attention-deficit/hyperactivity disorder, oppositional symptoms. San Francisco, CA: Annual Meeting of the American Psychiatric Association, May 2009(abstract).

Greenhill L , Beyer DH , Finkleson J , Shaffer D , Biederman J , Conners CK , Gillberg C , Huss M , Jensen P , Kennedy JL , Klein R , Rapoport J , Sagvolden T , Spencer T , Swanson JM , Volkow N . Guidelines and algorithms for the use of methylphenidate in children with Attention Deficit/Hyperactivity Disorder. J Atten Disord, 6:S89–S100. 2002.

Handen BL , Sahl R , Hardan AY . Guanfacine in children with autism and/or intellectual disabilities. J Dev Behav Pediatr, 29:303–308. 2008.

Lecavalier L . Behavioral and emotional problems in young people with pervasive developmental disorders: Relative prevalence, effects of subjects characteristics, and empirical classification. J Autism Dev Disord, 36:1101–1114. 2006.

Leucht S , Engel RR . The relative sensitivity of the clinical global impressions scale and the brief psychiatric rating scale in antipsychotic drug trials. Neuropsychopharmacology, 31:406–412. 2006.

Merck. www.merck.com/mmpe/lexicomp/guanfacine.html. 2010 May 282010.

Posey DJ , McDougle CJ . Guanfacine and guanfacine extended release: Treatment for ADHD and related disorders. CNS Drug Rev, 13:465–474. 2007.

Posey DJ , Puntney JI , Sasher TM , Kem DL , McDougle CJ . Guanfacine treatment of hyperactivity and inattention in pervasive developmental disorders: A retrospective analysis of 80 cases. J Child Adolesc Psychopharmacol, 14:233–241. 2004.

Research Units on Pediatric Psychopharmacology (RUPP) Autism Network:. Randomized, controlled, crossover trial of methylphenidate in pervasive developmental disorders with hyperactivity. Arch Gen Psychiatry, 62:1266–1274. 2005.

Sallee FR . Guanfacine extended release for ADHD. Curr Psychiatry, 9:49–60. 2009.

Sallee F , McGough J , Wigal T , Donahue J , Lyne A , Biederman J . for the SPD503 Study Group. Guanfacine extended release in children and adolescents with attention deficit hyperactivity disorder: A placebo-controlled trial. J Am Acad Child Adolesc Psychiatry, 48:155–165. 2009.

Scahill L , Aman MG , McDougle CJ , McCracken JT , Tierney E , Dziura J , Arnold LE , Posey D , Young C , Shah B , Ghuman J , Ritz L , Vitiello B . A prospective open trial of guanfacine in children with pervasive developmental disorders. J Child Adolesc Psychopharmacol, 16:589–598. 2006.