Restricted accessResearch articleFirst published online 2014-02
Functional Clustering of the Human Inferior Parietal Lobule by Whole-Brain Connectivity Mapping of Resting-State Functional Magnetic Resonance Imaging Signals
The human inferior parietal lobule (IPL) comprised the lateral bank of the intraparietal sulcus, angular gyrus, and supramarginal gyrus, defined on the basis of anatomical landmarks and cytoarchitectural organization of neurons. However, it is not clear as to whether the three areas represent functional subregions within the IPL. For instance, imaging studies frequently identified clusters of activities that cut across areal boundaries. Here, we used resting-state functional magnetic resonance imaging (fMRI) data to examine how individual voxels within the IPL are best clustered according to their connectivity to the whole brain. The results identified a best estimate of seven clusters that are hierarchically arranged as the anterior, middle, and posterior subregions. The anterior, middle, and posterior IPL are each significantly connected to the somatomotor areas, superior/middle/inferior frontal gyri, and regions of the default mode network. This functional segregation is supported by recent cytoarchitechtonics and tractography studies. IPL showed hemispheric differences in connectivity that accord with a predominantly left parietal role in tool use and language processing and a right parietal role in spatial attention and mathematical cognition. The functional clusters may also provide a more parsimonious and perhaps even accurate account of regional activations of the IPL during a variety of cognitive challenges, as reported in earlier fMRI studies.
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References
1.
AnsariD. 2008. Effects of development and enculturation on number representation in the brain. Nat Rev Neurosci, 9:278–291.
AstafievSV, ShulmanGL, StanleyCM, SnyderAZ, Van EssenDC, CorbettaM. 2003. Functional organization of human intraparietal and frontal cortex for attending, looking, and pointing. J Neurosci, 23:4689–4699.
4.
AwadM, WarrenJE, ScottSK, TurkheimerFE, WiseRJ. 2007. A common system for the comprehension and production of narrative speech. J Neurosci, 27:11455–11464.
5.
BarnesKA, CohenAL, PowerJD, NelsonSM, DosenbachYB, MiezinFM, PetersenSE, SchlaggarBL. 2010. Identifying basal ganglia divisions in individuals using resting-state functional connectivity MRI. Front Syst Neurosci, 4:18.
6.
BeauchampMS, PetitL, EllmoreTM, IngeholmJ, HaxbyJV. 2001. A parametric fMRI study of overt and covert shifts of visuospatial attention. Neuroimage, 14:310–321.
7.
BerryKJ, MielkePWJr., 2000. A Monte Carlo investigation of the Fisher Z transformation for normal and nonnormal distributions. Psychol Rep, 87:1101–1114.
8.
BinderJR, DesaiRH, GravesWW, ConantLL. 2009. Where is the semantic system? A critical review and meta-analysis of 120 functional neuroimaging studies. Cereb Cortex, 19:2767–2796.
9.
BiswalB, YetkinFZ, HaughtonVM, HydeJS. 1995. Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn Reson Med, 34:537–541.
BledowskiC, PrvulovicD, GoebelR, ZanellaFE, LindenDE. 2004. Attentional systems in target and distractor processing: a combined ERP and fMRI study. Neuroimage, 22:530–540.
12.
BraverTS, BarchDM, GrayJR, MolfeseDL, SnyderA. 2001. Anterior cingulate cortex and response conflict: effects of frequency, inhibition and errors. Cereb Cortex, 11:825–836.
13.
BrownsettSL, WiseRJ. 2010. The contribution of the parietal lobes to speaking and writing. Cereb Cortex, 20:517–523.
14.
BucknerRL, Andrews-HannaJR, SchacterDL. 2008. The brain's default network: anatomy, function, and relevance to disease. Ann N Y Acad Sci, 1124:1–38.
15.
CabezaR, CiaramelliE, OlsonIR, MoscovitchM. 2008. The parietal cortex and episodic memory: an attentional account. Nat Rev Neurosci, 9:613–625.
16.
CansinoS, MaquetP, DolanRJ, RuggMD. 2002. Brain activity underlying encoding and retrieval of source memory. Cereb Cortex, 12:1048–1056.
17.
CaseyBJ, ThomasKM, WelshTF, BadgaiyanRD, EccardCH, JenningsJR, CroneEA. 2000. Dissociation of response conflict, attentional selection, and expectancy with functional magnetic resonance imaging. Proc Natl Acad Sci U S A, 97:8728–8733.
18.
CaspersS, EickhoffSB, GeyerS, ScheperjansF, MohlbergH, ZillesK, AmuntsK. 2008. The human inferior parietal lobule in stereotaxic space. Brain Struct Funct, 212:481–495.
19.
CaspersS, EickhoffSB, RickT, von KapriA, KuhlenT, HuangR, ShahNJ, ZillesK. 2011. Probabilistic fibre tract analysis of cytoarchitectonically defined human inferior parietal lobule areas reveals similarities to macaques. Neuroimage, 58:362–380.
20.
CaspersS, GeyerS, SchleicherA, MohlbergH, AmuntsK, ZillesK. 2006. The human inferior parietal cortex: cytoarchitectonic parcellation and interindividual variability. Neuroimage, 33:430–448.
21.
CaudaF, GeminianiG, D'AgataF, SaccoK, DucaS, BagshawAP, CavannaAE. 2010. Functional connectivity of the posteromedial cortex. PLoS One, 5:e13107.
22.
ChambersCD, PayneJM, StokesMG, MattingleyJB. 2004. Fast and slow parietal pathways mediate spatial attention. Nat Neurosci, 7:217–218.
23.
CharlesF, BondJ, RichardsonK. 2004. Seeing the fisher z-transformation. Psychometrika, 69:291–303.
24.
ChenG, ChenG, XieC, LiSJ. 2011. Negative functional connectivity and its dependence on the shortest path length of positive network in the resting-state human brain. Brain Connect, 1:195–206.
25.
ChochonF, CohenL, van de MoortelePF, DehaeneS. 1999. Differential contributions of the left and right inferior parietal lobules to number processing. J Cogn Neurosci, 11:617–630.
26.
ChoiHJ, ZillesK, MohlbergH, SchleicherA, FinkGR, ArmstrongE, AmuntsK. 2006. Cytoarchitectonic identification and probabilistic mapping of two distinct areas within the anterior ventral bank of the human intraparietal sulcus. J Comp Neurol, 495:53–69.
27.
ChongMS, SahadevanS. 2005. Preclinical Alzheimer's disease: diagnosis and prediction of progression. Lancet Neurol, 4:576–579.
28.
ChouTL, BoothJR, BitanT, BurmanDD, BigioJD, ConeNE, LuD, CaoF. 2006a. Developmental and skill effects on the neural correlates of semantic processing to visually presented words. Hum Brain Mapp, 27:915–924.
29.
ChouTL, BoothJR, BurmanDD, BitanT, BigioJD, LuD, ConeNE. 2006b. Developmental changes in the neural correlates of semantic processing. Neuroimage, 29:1141–1149.
30.
CiaramelliE, GradyCL, MoscovitchM. 2008. Top-down and bottom-up attention to memory: a hypothesis (AtoM) on the role of the posterior parietal cortex in memory retrieval. Neuropsychologia, 46:1828–1851.
ClaeysKG, LindseyDT, De SchutterE, OrbanGA. 2003. A higher order motion region in human inferior parietal lobule: evidence from fMRI. Neuron, 40:631–642.
33.
ClarkD, WagnerAD. 2003. Assembling and encoding word representations: fMRI subsequent memory effects implicate a role for phonological control. Neuropsychologia, 41:304–317.
34.
Cohen KadoshR, Cohen KadoshK, KaasA, HenikA, GoebelR. 2007. Notation-dependent and -independent representations of numbers in the parietal lobes. Neuron, 53:307–314.
35.
CohenL, DehaeneS, ChochonF, LehericyS, NaccacheL. 2000. Language and calculation within the parietal lobe: a combined cognitive, anatomical and fMRI study. Neuropsychologia, 38:1426–1440.
36.
ConnollyJD, GoodaleMA, MenonRS, MunozDP. 2002. Human fMRI evidence for the neural correlates of preparatory set. Nat Neurosci, 5:1345–1352.
37.
CorbettaM, KincadeJM, OllingerJM, McAvoyMP, ShulmanGL. 2000. Voluntary orienting is dissociated from target detection in human posterior parietal cortex. Nat Neurosci, 3:292–297.
38.
CorbettaM, ShulmanGL. 2002. Control of goal-directed and stimulus-driven attention in the brain. Nat Rev Neurosci, 3:201–215.
39.
CordesD, HaughtonVM, ArfanakisK, CarewJD, TurskiPA, MoritzCH, QuigleyMA, MeyerandME. 2001. Frequencies contributing to functional connectivity in the cerebral cortex in “resting-state” data. AJNR Am J Neuroradiol, 22:1326–1333.
40.
DaselaarSM, FleckMS, CabezaR. 2006. Triple dissociation in the medial temporal lobes: recollection, familiarity, and novelty. J Neurophysiol, 96:1902–1911.
41.
DaselaarSM, PrinceSE, CabezaR. 2004. When less means more: deactivations during encoding that predict subsequent memory. Neuroimage, 23:921–927.
42.
DavachiL, MarilA, WagnerAD. 2001. When keeping in mind supports later bringing to mind: neural markers of phonological rehearsal predict subsequent remembering. J Cogn Neurosci, 13:1059–1070.
43.
De RenziE. 1985. Methods of limb apraxia examination and their bearing on the interpretation of the disorder. In: RoyEA (ed.) Neuropsychological Studies of Apraxia and Related Disorders. Amsterdam, Netherlands: Elsevier; pp. 45–64.
44.
DehaeneS, MolkoN, CohenL, WilsonAJ. 2004. Arithmetic and the brain. Curr Opin Neurobiol, 14:218–224.
EgnerT, MontiJM, TrittschuhEH, WienekeCA, HirschJ, MesulamMM. 2008. Neural integration of top-down spatial and feature-based information in visual search. J Neurosci, 28:6141–6151.
49.
EldridgeLL, KnowltonBJ, FurmanskiCS, BookheimerSY, EngelSA. 2000. Remembering episodes: a selective role for the hippocampus during retrieval. Nat Neurosci, 3:1149–1152.
50.
FairDA, SchlaggarBL, CohenAL, MiezinFM, DosenbachNU, WengerKK, FoxMD, SnyderAZ, RaichleME, PetersenSE. 2007. A method for using blocked and event-related fMRI data to study “resting state” functional connectivity. Neuroimage, 35:396–405.
51.
FenkerDB, SchottBH, Richardson-KlavehnA, HeinzeHJ, DuzelE. 2005. Recapitulating emotional context: activity of amygdala, hippocampus and fusiform cortex during recollection and familiarity. Eur J Neurosci, 21:1993–1999.
52.
FoxMD, RaichleME. 2007. Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. Nat Rev Neurosci, 8:700–711.
53.
FoxMD, SnyderAZ, VincentJL, CorbettaM, Van EssenDC, RaichleME. 2005. The human brain is intrinsically organized into dynamic, anticorrelated functional networks. Proc Natl Acad Sci U S A, 102:9673–9678.
54.
FoxMD, ZhangD, SnyderAZ, RaichleME. 2009. The global signal and observed anticorrelated resting state brain networks. J Neurophysiol, 101:3270–3283.
55.
FranssonP. 2005. Spontaneous low-frequency BOLD signal fluctuations: an fMRI investigation of the resting-state default mode of brain function hypothesis. Hum Brain Mapp, 26:15–29.
56.
FristonK, AshburnerJ, FrithC, PoloneJ, HeatherJ, FrackowiakR. 1995. Spatial registration and normalization of images. Hum Brain Mapp, 2:165–189.
57.
FulbrightRK, MolfeseDL, StevensAA, SkudlarskiP, LacadieCM, GoreJC. 2000. Cerebral activation during multiplication: a functional MR imaging study of number processing. AJNR Am J Neuroradiol, 21:1048–1054.
58.
GareyLJ. 2006. Brodmann's Localisation in the Cerebral Cortex. New York: Springer.
59.
GentleJE, HärdleW, MoriY. 2004. Handbook of Computational Statistics: Concepts and Methods. Berlin: Springer-Verlag.
60.
GoldenbergG, KarnathHO. 2006. The neural basis of imitation is body part specific. J Neurosci, 26:6282–6287.
61.
GrabnerRH, IschebeckA, ReishoferG, KoschutnigK, DelazerM, EbnerF, NeuperC. 2009. Fact learning in complex arithmetic and figural-spatial tasks: the role of the angular gyrus and its relation to mathematical competence. Hum Brain Mapp, 30:2936–2952.
62.
GreeneSJ, KillianyRJ. 2010. Subregions of the inferior parietal lobule are affected in the progression to Alzheimer's disease. Neurobiol Aging, 31:1304–1311.
63.
GreiciusMD, KrasnowB, ReissAL, MenonV. 2003. Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proc Natl Acad Sci U S A, 100:253–258.
HanggiJ, StrefferJ, JanckeL, HockC. 2011. Volumes of lateral temporal and parietal structures distinguish between healthy aging, mild cognitive impairment, and Alzheimer's disease. J Alzheimers Dis, 26:719–734.
66.
HensonRN, RuggMD, ShalliceT, JosephsO, DolanRJ. 1999. Recollection and familiarity in recognition memory: an event-related functional magnetic resonance imaging study. J Neurosci, 19:3962–3972.
67.
HopfingerJB, BuonocoreMH, MangunGR. 2000. The neural mechanisms of top-down attentional control. Nat Neurosci, 3:284–291.
68.
HusainM, NachevP. 2007. Space and the parietal cortex. Trends Cogn Sci, 11:30–36.
69.
HutchinsonJB, UncapherMR, WagnerAD. 2009. Posterior parietal cortex and episodic retrieval: convergent and divergent effects of attention and memory. Learn Mem, 16:343–356.
70.
IndovinaI, MacalusoE. 2007. Dissociation of stimulus relevance and saliency factors during shifts of visuospatial attention. Cereb Cortex, 17:1701–1711.
71.
IshibashiR, Lambon RalphMA, SaitoS, PobricG. 2011. Different roles of lateral anterior temporal lobe and inferior parietal lobule in coding function and manipulation tool knowledge: evidence from an rTMS study. Neuropsychologia, 49:1128–1135.
72.
JackAI, PatelGH, AstafievSV, SnyderAZ, AkbudakE, ShulmanGL, CorbettaM. 2007. Changing human visual field organization from early visual to extra-occipital cortex. PLoS One, 2:e452.
73.
JenkinsGM, WattsDG. 1968. Spectral Analysis and Its Applications. San Francisco, CA: Holden-Day.
74.
Johnson-FreySH, Newman-NorlundR, GraftonST. 2005. A distributed left hemisphere network active during planning of everyday tool use skills. Cereb Cortex, 15:681–695.
75.
JohnsonJD, RuggMD. 2007. Recollection and the reinstatement of encoding-related cortical activity. Cereb Cortex, 17:2507–2515.
76.
KahntT, ChangLJ, ParkSQ, HeinzleJ, HaynesJD. 2012. Connectivity-based parcellation of the human orbitofrontal cortex. J Neurosci, 32:6240–6250.
77.
KiehlKA, LaurensKR, DutyTL, ForsterBB, LiddlePF. 2001. Neural sources involved in auditory target detection and novelty processing: an event-related fMRI study. Psychophysiology, 38:133–142.
78.
KimJH, LeeJM, JoHJ, KimSH, LeeJH, KimST, SeoSW, CoxRW, NaDL, KimSI, SaadZS. 2010. Defining functional SMA and pre-SMA subregions in human MFC using resting state fMRI: functional connectivity-based parcellation method. Neuroimage, 49:2375–2386.
79.
KincadeJM, AbramsRA, AstafievSV, ShulmanGL, CorbettaM. 2005. An event-related functional magnetic resonance imaging study of voluntary and stimulus-driven orienting of attention. J Neurosci, 25:4593–4604.
80.
KrogerJK, NystromLE, CohenJD, Johnson-LairdPN. 2008. Distinct neural substrates for deductive and mathematical processing. Brain Res, 1243:86–103.
81.
LiangP, WangZ, YangY, LiK. 2012. Three subsystems of the inferior parietal cortex are differently affected in mild cognitive impairment. J Alzheimers Dis, 30:475–487.
82.
LindenDE, PrvulovicD, FormisanoE, VollingerM, ZanellaFE, GoebelR, DierksT. 1999. The functional neuroanatomy of target detection: an fMRI study of visual and auditory oddball tasks. Cereb Cortex, 9:815–823.
83.
LoweMJ, MockBJ, SorensonJA. 1998. Functional connectivity in single and multislice echoplanar imaging using resting-state fluctuations. Neuroimage, 7:119–132.
84.
MacalusoE, PatriaF. 2007. Spatial re-orienting of visual attention along the horizontal or the vertical axis. Exp Brain Res, 180:23–34.
85.
MacQueenJB. 1967. Some methods for classification and analysis of multivariate observations. In: 5-th Berkeley Symposium on Mathematical Statistics and Probability, vol. 1. Berkeley, CA: University of California Press; pp. 281–297.
86.
MarguliesDS, KellyAM, UddinLQ, BiswalBB, CastellanosFX, MilhamMP. 2007. Mapping the functional connectivity of anterior cingulate cortex. Neuroimage, 37:579–588.
87.
MarguliesDS, VincentJL, KellyC, LohmannG, UddinLQ, BiswalBB, VillringerA, CastellanosFX, MilhamMP, PetridesM. 2009. Precuneus shares intrinsic functional architecture in humans and monkeys. Proc Natl Acad Sci U S A, 106:20069–20074.
MarsRB, JbabdiS, SalletJ, O'ReillyJX, CroxsonPL, OlivierE, NoonanMP, BergmannC, MitchellAS, BaxterMG, BehrensTE, Johansen-BergH, TomassiniV, MillerKL, RushworthMF. 2011. Diffusion-weighted imaging tractography-based parcellation of the human parietal cortex and comparison with human and macaque resting-state functional connectivity. J Neurosci, 31:4087–4100.
90.
Martinez-TrujilloJC, CheyneD, GaetzW, SimineE, TsotsosJK. 2007. Activation of area MT/V5 and the right inferior parietal cortex during the discrimination of transient direction changes in translational motion. Cereb Cortex, 17:1733–1739.
91.
MayerAR, HarringtonD, AdairJC, LeeR. 2006. The neural networks underlying endogenous auditory covert orienting and reorienting. Neuroimage, 30:938–949.
92.
MenonV, FordJM, LimKO, GloverGH, PfefferbaumA. 1997. Combined event-related fMRI and EEG evidence for temporal-parietal cortex activation during target detection. Neuroreport, 8:3029–3037.
93.
MontaldiD, SpencerTJ, RobertsN, MayesAR. 2006. The neural system that mediates familiarity memory. Hippocampus, 16:504–520.
94.
MurphyK, BirnRM, HandwerkerDA, JonesTB, BandettiniPA. 2009. The impact of global signal regression on resting state correlations: are anti-correlated networks introduced?. Neuroimage, 44:893–905.
95.
NaccacheL, DehaeneS. 2001. The priming method: imaging unconscious repetition priming reveals an abstract representation of number in the parietal lobes. Cereb Cortex, 11:966–974.
96.
NelsonPT, AbnerEL, ScheffSW, SchmittFA, KryscioRJ, JichaGA, SmithCD, PatelE, MarkesberyWR. 2009. Alzheimer's-type neuropathology in the precuneus is not increased relative to other areas of neocortex across a range of cognitive impairment. Neurosci Lett, 450:336–339.
97.
NelsonSM, CohenAL, PowerJD, WigGS, MiezinFM, WheelerME, VelanovaK, DonaldsonDI, PhillipsJS, SchlaggarBL, PetersenSE. 2010. A parcellation scheme for human left lateral parietal cortex. Neuron, 67:156–170.
98.
NeufangS, AkhrifA, RiedlV, ForstlH, KurzA, ZimmerC, SorgC, WohlschlagerAM. 2011. Disconnection of frontal and parietal areas contributes to impaired attention in very early Alzheimer's disease. J Alzheimers Dis, 25:309–321.
99.
NiederA, DehaeneS. 2009. Representation of number in the brain. Annu Rev Neurosci, 32:185–208.
100.
O'ReillyJX, BeckmannCF, TomassiniV, RamnaniN, Johansen-BergH. 2010. Distinct and overlapping functional zones in the cerebellum defined by resting state functional connectivity. Cereb Cortex, 20:953–965.
101.
OttenLJ, RuggMD. 2001. When more means less: neural activity related to unsuccessful memory encoding. Curr Biol, 11:1528–1530.
102.
PassinghamRE, StephanKE, KotterR. 2002. The anatomical basis of functional localization in the cortex. Nat Rev Neurosci, 3:606–616.
103.
PazzagliaM, SmaniaN, CoratoE, AgliotiSM. 2008. Neural underpinnings of gesture discrimination in patients with limb apraxia. J Neurosci, 28:3030–3041.
104.
PeetersR, SimoneL, NelissenK, Fabbri-DestroM, VanduffelW, RizzolattiG, OrbanGA. 2009. The representation of tool use in humans and monkeys: common and uniquely human features. J Neurosci, 29:11523–11539.
105.
PennyWD, HolmesAP, FristonK. 2004. Random-effects analysis. In: FrackowiakR, et al. (eds.) Human Brain Function. San Diego, CA: Academic Press; pp. 843–850.
106.
PessoaL, GutierrezE, BandettiniP, UngerleiderL. 2002. Neural correlates of visual working memory: fMRI amplitude predicts task performance. Neuron, 35:975–987.
107.
PiazzaM, PinelP, Le BihanD, DehaeneS. 2007. A magnitude code common to numerosities and number symbols in human intraparietal cortex. Neuron, 53:293–305.
108.
PowerJD, CohenAL, NelsonSM, WigGS, BarnesKA, ChurchJA, VogelAC, LaumannTO, MiezinFM, SchlaggarBL, PetersenSE. 2011. Functional network organization of the human brain. Neuron, 72:665–678.
109.
RaglandJD, ValdezJN, LougheadJ, GurRC, GurRE. 2006. Functional magnetic resonance imaging of internal source monitoring in schizophrenia: recognition with and without recollection. Schizophr Res, 87:160–171.
110.
RaichleME, MacLeodAM, SnyderAZ, PowersWJ, GusnardDA, ShulmanGL. 2001. A default mode of brain function. Proc Natl Acad Sci U S A, 98:676–682.
111.
RaposoA, MossHE, StamatakisEA, TylerLK. 2006. Repetition suppression and semantic enhancement: an investigation of the neural correlates of priming. Neuropsychologia, 44:2284–2295.
112.
RomboutsSA, StamCJ, KuijerJP, ScheltensP, BarkhofF. 2003. Identifying confounds to increase specificity during a “no task condition”. Evidence for hippocampal connectivity using fMRI. Neuroimage, 20:1236–1245.
113.
RushworthMF, BehrensTE, Johansen-BergH. 2006. Connection patterns distinguish 3 regions of human parietal cortex. Cereb Cortex, 16:1418–1430.
114.
RushworthMF, Johansen-BergH, GobelSM, DevlinJT. 2003. The left parietal and premotor cortices: motor attention and selection. Neuroimage, 20Suppl 1:S89–S100.
115.
RushworthMF, KramsM, PassinghamRE. 2001. The attentional role of the left parietal cortex: the distinct lateralization and localization of motor attention in the human brain. J Cogn Neurosci, 13:698–710.
116.
RushworthMF, NixonPD, RenowdenS, WadeDT, PassinghamRE. 1997. The left parietal cortex and motor attention. Neuropsychologia, 35:1261–1273.
117.
ScheperjansF, EickhoffSB, HomkeL, MohlbergH, HermannK, AmuntsK, ZillesK. 2008a. Probabilistic maps, morphometry, and variability of cytoarchitectonic areas in the human superior parietal cortex. Cereb Cortex, 18:2141–2157.
118.
ScheperjansF, HermannK, EickhoffSB, AmuntsK, SchleicherA, ZillesK. 2008b. Observer-independent cytoarchitectonic mapping of the human superior parietal cortex. Cereb Cortex, 18:846–867.
119.
SchmahmannJD, DoyonJ, McDonaldD, HolmesC, LavoieK, HurwitzAS, KabaniN, TogaA, EvansA, PetridesM. 1999. Three-dimensional MRI atlas of the human cerebellum in proportional stereotaxic space. Neuroimage, 10:233–260.
120.
SchmahmannJD, DoyonJ, TogaA, PetridesM, EvansA. 2000. MRI Atlas of the Human Cerebellum. San Diego, CA: Academic Press.
121.
SchwarzG. 1978. Estimating the dimension of a model. Ann Stat, 6:461–464.
122.
SeghierML. 2013. The angular gyrus: multiple functions and multiple subdivisions. Neuroscientist, 19:43–61.
123.
SharpDJ, AwadM, WarrenJE, WiseRJ, ViglioccoG, ScottSK. 2010. The neural response to changing semantic and perceptual complexity during language processing. Hum Brain Mapp, 31:365–377.
124.
ShulmanGL, d'AvossaG, TansyAP, CorbettaM. 2002. Two attentional processes in the parietal lobe. Cereb Cortex, 12:1124–1131.
125.
Singh-CurryV, HusainM. 2009. The functional role of the inferior parietal lobe in the dorsal and ventral stream dichotomy. Neuropsychologia, 47:1434–1448.
126.
SommerT, RoseM, BuchelC. 2006. Dissociable parietal systems for primacy and subsequent memory effects. Neurobiol Learn Mem, 85:243–251.
127.
StevensMC, CalhounVD, KiehlKA. 2005. Hemispheric differences in hemodynamics elicited by auditory oddball stimuli. Neuroimage, 26:782–792.
128.
SylvesterCM, ShulmanGL, JackAI, CorbettaM. 2007. Asymmetry of anticipatory activity in visual cortex predicts the locus of attention and perception. J Neurosci, 27:14424–14433.
129.
Tzourio-MazoyerN, LandeauB, PapathanassiouD, CrivelloF, EtardO, DelcroixN, MazoyerB, JoliotM. 2002. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage, 15:273–289.
UddinLQ, SupekarK, AminH, RykhlevskaiaE, NguyenDA, GreiciusMD, MenonV. 2010. Dissociable connectivity within human angular gyrus and intraparietal sulcus: evidence from functional and structural connectivity. Cereb Cortex, 20:2636–2646.
132.
UncapherMR, WagnerAD. 2009. Posterior parietal cortex and episodic encoding: insights from fMRI subsequent memory effects and dual-attention theory. Neurobiol Learn Mem, 91:139–154.
133.
VigneauM, BeaucousinV, HervePY, DuffauH, CrivelloF, HoudeO, MazoyerB, Tzourio-MazoyerN. 2006. Meta-analyzing left hemisphere language areas: phonology, semantics, and sentence processing. Neuroimage, 30:1414–1432.
134.
VilbergKL, RuggMD. 2007. Dissociation of the neural correlates of recognition memory according to familiarity, recollection, and amount of recollected information. Neuropsychologia, 45:2216–2225.
135.
VilbergKL, RuggMD. 2008. Memory retrieval and the parietal cortex: a review of evidence from a dual-process perspective. Neuropsychologia, 46:1787–1799.
136.
VosselS, ThielCM, FinkGR. 2006. Cue validity modulates the neural correlates of covert endogenous orienting of attention in parietal and frontal cortex. Neuroimage, 32:1257–1264.
137.
WagnerAD, DavachiL. 2001. Cognitive neuroscience: forgetting of things past. Curr Biol, 11:R964–R967.
WangJ, FanL, ZhangY, LiuY, JiangD, ZhangY, YuC, JiangT. 2012. Tractography-based parcellation of the human left inferior parietal lobule. Neuroimage, 63:641–652.
140.
WeissenbacherA, KasessC, GerstlF, LanzenbergerR, MoserE, WindischbergerC. 2009. Correlations and anticorrelations in resting-state functional connectivity MRI: a quantitative comparison of preprocessing strategies. Neuroimage, 47:1408–1416.
141.
WheelerME, BucknerRL. 2004. Functional-anatomic correlates of remembering and knowing. Neuroimage, 21:1337–1349.
142.
WoodruffCC, JohnsonJD, UncapherMR, RuggMD. 2005. Content-specificity of the neural correlates of recollection. Neuropsychologia, 43:1022–1032.
143.
XiaM, HeY. 2011. Magnetic resonance imaging and graph theoretical analysis of complex brain networks in neuropsychiatric disorders. Brain Connect, 1:349–365.
YeoBT, KrienenFM, SepulcreJ, SabuncuMR, LashkariD, HollinsheadM, RoffmanJL, SmollerJW, ZolleiL, PolimeniJR, FischlB, LiuH, BucknerRL. 2011. The organization of the human cerebral cortex estimated by intrinsic functional connectivity. J Neurophysiol, 106:1125–1165.
146.
ZahnR, BuechertM, OvermansJ, TalazkoJ, SpechtK, KoCW, ThielT, KaufmannR, DykierekP, JuenglingF, HullM. 2005. Mapping of temporal and parietal cortex in progressive nonfluent aphasia and Alzheimer's disease using chemical shift imaging, voxel-based morphometry and positron emission tomography. Psychiatry Res, 140:115–131.
147.
ZhangD, SnyderAZ, FoxMD, SansburyMW, ShimonyJS, RaichleME. 2008. Intrinsic functional relations between human cerebral cortex and thalamus. J Neurophysiol, 100:1740–1748.
148.
ZhangD, SnyderAZ, ShimonyJS, FoxMD, RaichleME. 2010. Noninvasive functional and structural connectivity mapping of the human thalamocortical system. Cereb Cortex, 20:1187–1194.
149.
ZhangH, ChenC, ZhouX. 2012b. Neural correlates of numbers and mathematical terms. Neuroimage, 60:230–240.
150.
ZhangS, IdeJS, LiCS. 2012a. Resting-state functional connectivity of the medial superior frontal cortex. Cereb Cortex, 22:99–111.
151.
ZhangS, LiCS. 2012. Functional connectivity mapping of the human precuneus by resting state fMRI. Neuroimage, 59:3548–3562.
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