PetersenOH. Stimulus-secretion coupling: Cytoplasmic calcium signals and the control of ion channels in exocrine acinar cells. J Physiol, 1992; 448:1–51. DOI: 10.1113/jphysiol.1992.sp019028.
3.
PetersenOH. Ca2+ signalling and Ca2+-activated ion channels in exocrine acinar cells. Cell Calcium, 2005; 38:171–200. DOI: 10.1016/j.ceca.2005.06.024.
4.
PetersenOH. The dependence of the transmembrane salivary secretory potential on the external potassium and sodium concentration. J Physiol, 1970; 210:205–215. DOI: 10.1113/jphysiol.1970.sp009204.
5.
PetersenOH. Mechanism of action of pancreozymin and acetylcholine on pancreatic acinar cells. Nat New Biol, 1973; 244:73. DOI: 10.1038/newbio244073a0.
6.
IwatsukiN, PetersenOH. Pancreatic acinar cells: Localization of acetylcholine receptors and the importance of chloride and calcium for acetylcholine-evoked depolarization. J Physiol, 1977; 269:723–733. DOI: 10.1113/jphysiol.1977.sp011925.
7.
IwatsukiN, PetersenOH. Electrical coupling and uncoupling of exocrine acinar cells. J Cell Biol, 1978; 79:533–545. DOI: 10.1083/jcb.79.2.533.
8.
IwatsukiN, PetersenOH. Acetylcholine-like effects of intracellular calcium application in pancreatic acinar cells. Nature, 1977; 268:147–149. DOI: 10.1038/268147a0.
9.
IwatsukiN, PetersenOH. Pancreatic acinar cells: Acetylcholine-evoked electrical uncoupling and its ionic dependency. J Physiol, 1978; 274:81–106. DOI: 10.1113/jphysiol.1978.sp012135.
10.
NielsenSP, PetersenOH. Transport of calcium in the perfused submandibular gland of the cat. J Physiol, 1972; 223:685–697. DOI: 10.1113/jphysiol.1972.sp009869.
PetersenOH, IwatsukiN. The role of calcium in pancreatic acinar cell stimulus-secretion coupling: An electrophysiological approach. Ann N Y Acad Sci, 1978; 307:599–617. DOI: 10.1111/j.1749-6632.1978.tb41984.x.
13.
NeherE, SakmannB. Single-channel currents recorded from membrane of denervated frog muscle fibres. Nature, 1976; 260:799–802. DOI: 10.1038/260799a0.
14.
SigworthFJ, NeherE. Single Na+ channel currents observed in cultured rat muscle cells. Nature, 1980; 287:447–449. DOI: 10.1038/287447a0.
15.
MaruyamaY, PetersenOH. Single-channel currents in isolated patches of plasma membrane from basal surface of pancreatic acini. Nature, 1982; 299:159–161. DOI: 10.1038/299159a0.
16.
SuzukiK, PetersenOH. Patch-clamp study of single-channel and whole-cell K+ currents in guinea pig pancreatic acinar cells. Am J Physiol, 1988; 255:G275–G285. DOI: 10.1152/ajpgi.1988.255.3.G275.
17.
MaruyamaY, PetersenOH. Cholecystokinin activation of single-channel currents is mediated by internal messenger in pancreatic acinar cells. Nature, 1982; 300:61–63. DOI: 10.1038/300061a0.
18.
SakmannB, Neher E (eds) Single-Channel Recording. New York: Plenum Press, 1983.
19.
MaruyamaY, GallacherDV, PetersenOH. Voltage and Ca2+-activated K+ channel in baso-lateral acinar cell membranes of mammalian salivary glands. Nature, 1983; 302:827–829. DOI: 10.1038/302827a0.
20.
MaruyamaY, PetersenOH, FlanaganP, et al.Quantification of Ca2+-activated K+ channels under hormonal control in pig pancreas acinar cells. Nature, 1983; 305:228–232. DOI: 10.1038/305228a0.
21.
PetersenOH, FindlayI, IwatsukiN, et al.Human pancreatic acinar cells: Studies of stimulus-secretion coupling. Gastroenterology, 1985; 89:109–117. DOI: 10.1016/0016-5085(85)90751-6.
22.
OsipchukYV, WakuiM, YuleDI, et al.Cytoplasmic Ca2+ oscillations evoked by receptor stimulation, G-protein activation, internal application of inositol trisphosphate or Ca2+: Simultaneous microfluorimetry and Ca2+ dependent Cl− current recording in single pancreatic acinar cells. EMBO J, 1990; 9:697–704.
23.
TrautmannA, MartyA. Activation of Ca-dependent K channels by carbamoylcholine in rat lacrimal glands. Proc Natl Acad Sci U S A, 1984; 81:611–615. DOI: 10.1073/pnas.81.2.611.
24.
MartyA, TanYP, TrautmannA. Three types of calcium-dependent channel in rat lacrimal glands. J Physiol, 1984; 357:293–325. DOI: 10.1113/jphysiol.1984.sp015501.
25.
MorrisAP, GallacherDV, IrvineRF, et al.Synergism of inositol trisphosphate and tetrakisphosphate in activating Ca2+-dependent K+ channels. Nature, 1987; 330:653–655. DOI: 10.1038/330653a0.
26.
PetersenOH, MaruyamaY. Calcium-activated potassium channels and their role in secretion. Nature, 1984; 307:693–696. DOI: 10.1038/307693a0.
27.
PetersenOH. Some factors influencing stimulation-induced release of potassium from the cat submandibular gland to fluid perfused through the gland. J Physiol, 1970; 208:431–447. DOI: 10.1113/jphysiol.1970.sp009129.
28.
SuzukiK, PetersenOH. The effect of Na+ and Cl− removal and of loop diuretics on acetylcholine-evoked membrane potential changes in mouse lacrimal acinar cells. Q J Exp Physiol, 1985; 70:437–445. DOI: 10.1113/expphysiol.1985.sp002927.
29.
ParkMK, LomaxRB, TepikinAV, et al.Local uncaging of caged Ca2+ reveals distribution of Ca2+-activated Cl− channels in pancreatic acinar cells. Proc Natl Acad Sci U S A, 2001; 98:10948–10953. DOI: 10.1073/pnas.181353798.
30.
PetersenOH, FindlayI. Electrophysiology of the pancreas. Physiol Rev, 1987; 67:1054–1116. DOI: 10.1152/physrev.1987.67.3.1054.
31.
RappPE, BerridgeMJ. The control of transepithelial potential oscillations in the salivary gland of Calliphora Erythrocephala. J Exp Biol, 1981; 93:119–132. DOI: 10.1242/jeb.93.1.119.
32.
WoodsN, CuthbertsonK, CobboldP. Repetitive transient rises in cytoplasmic free calcium in hormone-stimulated hepatocytes. Nature, 1986; 319:600–602. DOI: 10.1038/319600a0.
33.
WakuiM, PotterBV, PetersenOH. Pulsatile intracellular calcium release does not depend on fluctuations in inositol trisphosphate concentration. Nature, 1989; 339:317–320. DOI: 10.1038/339317a0.
34.
BezprozvannyI, WatrasJ, EhrlichBE. Bell-shaped calcium-response curves of Ins(1,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum. Nature, 1991; 351:751–754. DOI: 10.1038/351751a0.
35.
ThornP, LawrieAM, SmithPM, et al.Local and global cytosolic Ca2+ oscillations in exocrine cells evoked by agonists and inositol trisphosphate. Cell, 1993; 74:661–668. DOI: 10.1016/0092-8674(93)90513-p.
36.
MaruyamaY, PetersenOH. Delay in granular fusion evoked by repetitive cytosolic Ca2+ spikes in mouse pancreatic acinar cells. Cell Calcium, 1994; 16:419–430. DOI: 10.1016/0143-4160(94)90035-3.
37.
MaruyamaY, InookaG, LiYX, et al.Agonist-induced localized Ca2+ spikes directly triggering exocytotic secretion in exocrine pancreas. EMBO J, 1993; 12:3017–3022.
38.
StrebH, IrvineRF, BerridgeMJ, et al.Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate. Nature, 1983; 306:67–69. DOI: 10.1038/306067a0.
39.
HothM, PennerR. Depletion of intracellular calcium stores activates a calcium current in mast cells. Nature, 1992; 355:353–356. DOI: 10.1038/355353a0.
KimMS, HongJH, LiQ, et al.Deletion of TRPC3 in mice reduces store-operated Ca2+ influx and the severity of acute pancreatitis. Gastroenterology, 2009; 137:1509–1517. DOI: 10.1053/j.gastro.2009.07.042.
42.
KimMS, LeeKP, YangD, et al.Genetic and pharmacologic inhibition of the Ca2+ influx channel TRPC3 protects secretory epithelia from Ca2+-dependent toxicity. Gastroenterology, 2011; 140:2107–2115. DOI: 10.1053/j.gastro.2011.02.052.
43.
GerasimenkoJV, GryshchenkoO, FerdekPE, et al.Ca2+ release-activated Ca2+ channel blockade as a potential tool in antipancreatitis therapy. Proc Natl Acad Sci U S A, 2013; 110:13186–13191. DOI: 10.1073/pnas.1300910110.
44.
ThastrupO, CullenPJ, DrøbakBK, et al.Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase. Proc Natl Acad Sci U S A, 1990; 87:2466–2470. DOI: 10.1073/pnas.87.7.2466.
45.
WenL, VoroninaS, JavedMA, et al.Inhibitors of ORAI1 prevent cytosolic calcium-associated injury of human pancreatic acinar cells and acute pancreatitis in 3 mouse models. Gastroenterology, 2015; 149:481–492. DOI: 10.1053/j.gastro.2015.04.015.
46.
WaldronRT, ChenY, PhamH, et al.The Orai Ca2+ channel inhibitor CM4620 targets both parenchymal and immune cells to reduce inflammation in experimental acute pancreatitis. J Physiol, 2019; 597:3085–3105. DOI: 10.1113/JP277856.
47.
BruenC, MillerJ, WilburnJ, et al.Auxora for the treatment of patients with acute pancreatitis and accompanying systemic inflammatory response syndrome: Clinical development of a calcium release-activated calcium channel inhibitor. Pancreas, 2021; 50:537–543. DOI: 10.1097/MPA.0000000000001793.
48.
GryshchenkoO, GerasimenkoJV, GerasimenkoOV, et al.Ca2+ signals mediated by bradykinin type 2 receptors in normal pancreatic stellate cells can be inhibited by specific Ca2+ channel blockade. J Physiol, 2016; 594:281–293. DOI: 10.1113/JP271468.
49.
GerasimenkoJV, PetersenOH, GerasimenkoOV. SARS-CoV-2 S protein subunit 1 elicits Ca2+ influx—dependent Ca2+ signals in pancreatic stellate cells and macrophages in situ. Function, 2022; 3:zqac002. DOI:10.1093/function/zqac002.
50.
PetersenOH, GerasimenkoJV, GerasimenkoOV, et al.The roles of calcium and ATP in the physiology and pathology of the exocrine pancreas. Physiol Rev, 2021; 101:1691–1744. DOI: 10.1152/physrev.00003.2021.
