Late preterm infants (LPIs; born at 340/7 to 366/7 gestational weeks) and early term infants (ETIs; 370/7 to 386/7 gestational weeks) are at higher risk of morbidity and mortality compared with more mature infants. Breastfeeding can reduce these risks, but feeding difficulties are common among these infants and breastfeeding rates are low. We conducted a systematic review to identify the interventions available to improve any breastfeeding, exclusive breastfeeding, or breast milk yield.
Methods:
A literature search was performed up to February 23, 2022, using MEDLINE, CINAHL, Embase, and Google Scholar, and nine articles were included. Only one article was a randomized controlled trial, and only one included ETIs. The remaining articles were quasi-experimental and included only LPIs. Outcomes included breastfeeding duration, breastfeeding exclusivity, and/or breast milk production (volume) before 6 months actual age.
Results:
Professional support significantly improved exclusive breastfeeding rates. A breastfeeding education program delivered at the hospital with weekly telephone follow-up postdischarge significantly increased breastfeeding rates. Neither cup feeding nor early discharge (with in-home lactation support) improved breastfeeding rates, whereas rooming-in (versus direct admission to the neonatal intensive care unit) worsened exclusive breastfeeding rates.
Discussion:
This is the first systematic review to identify interventions available for both LPIs and ETIs. Overall, there are limited studies that investigate interventions promoting breastfeeding in these populations. However, breastfeeding support delivered by health care professionals seems to improve breastfeeding rates. The main limitations are the lack of randomization, blinding, and adjustment for confounding variables. Experimental studies with robust methodological design are needed.
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References
1.
BlencoweH, CousensS, OestergaardMZ, et al.National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: A systematic analysis and implications. Lancet, 2012; 379(9832):2162–2172; doi: 10.1016/S0140-6736(12)60820-4
2.
CrumpC.An overview of adult health outcomes after preterm birth. Early Hum Dev, 2020; 150:105187; doi: 10.1016/j.earlhumdev.2020.105187
3.
Committee on Obstetric Practice. ACOG committee opinion no. 404 April 2008. Late-preterm infants. Obstet Gynecol, 2008; 111(4):1029–1032; doi: 10.1097/AOG.0b013e31817327d0
4.
DavidoffMJ, DiasT, DamusK, et al.Changes in the gestational age distribution among US singleton births: Impact on rates of late preterm birth, 1992 to 2002. Semin Perinatol, 2006; 30(1):8–15; doi: 10.1053/j.semperi.2006.01.009
5.
WangML, DorerDJ, FlemingMP, et al.Clinical outcomes of near-term infants. Pediatrics, 2004; 114(2):372–376; doi: 10.1542/peds.114.2.372
6.
RichardsJL, KramarMS, Deb-RinkerP, et al.Temporal trends in late preterm and early term birth rates in 6 high-income countries in North America and Europe and association with clinician-initiated obstetric interventions. JAMA, 2016; 316(4):410–419; doi: 10.1001/jama.2016.9635
7.
EngleWA.Morbidity and mortality in late preterm and early term newborns: A continuum. Clin Perinatol, 2011; 38(3):493–516; doi: 10.1016/j.clp.2011.06.009
8.
BrownHK, SpeechleyKN, MacnabJ, et al.Neonatal morbidity associated with late preterm and early term birth: The roles of gestational age and biological determinants of preterm birth. Int J Epidemiol, 2014; 43(3):802–814; doi: 10.1093/ije/dyt251
9.
HackmanNM, Alligood-PercocoN, MartinA, et al.Reduced breastfeeding rates in firstborn late preterm and early term infants. Breastfeed Med, 2016; 11(3):119–125; doi: 10.1089/bfm.2015.0122
10.
GoyalNK, AttanasioLB, KozhimannilKB. Hospital care and early breastfeeding outcomes among late preterm, early-term, and term infants. Birth, 2014; 41(4):330–338; doi: 10.1111/birt.12135
11.
BoyleEM, JohnsonS, ManktelowB, et al.Neonatal outcomes and delivery of care for infants born late preterm or moderately preterm: A prospective population-based study. Arch Dis Child Fetal Neonatal Ed, 2015; 100(6):F479–F485; doi: 10.1136/archdischild-2014-307347
12.
KairLR, ColaizyTT. Breastfeeding continuation among late preterm infants: Barriers, facilitators, and any association with NICU admission?. Hosp Pediatr, 2016; 6(5):261–268; doi: 10.1542/hpeds.2015-0172
13.
CrippaBL, ColomboL, MorniroliD, et al.Do a few weeks matter? Late preterm infants and breastfeeding issues. Nutrients, 2019; 11(2):312; doi: 10.3390/nu11020312
14.
AndreasNJ, KampmannB, Le-DoareKM. Human breast milk: A review on its composition and bioactivity. Early Hum Dev, 2015; 91(11):629–635; doi: 10.1016/j.earlhumdev.2015.08.013
15.
CarpayNC, KakaroukasA, EmbletonND, et al.Barriers and facilitators to breastfeeding in moderate and late preterm infants: A systematic review. Breastfeed Med, 2021; 16(5):370–384; doi: 10.1089/bfm.2020.0379
16.
CartwrightJ, AtzT, NewmanS, et al.Integrative review of interventions to promote breastfeeding in the late preterm infant. J Obstet Gynecol Neonatal Nurs, 2017; 46(3):347–356; doi: 10.1016/j.jogn.2017.01.006
17.
AkersJ, Aguiar-IbáñezR, Baba-AkbariA, (eds). Systematic Reviews: CRD's Guidance for Undertaking Reviews in Health Care. Centre for Reviews and Dissemination, University of York: United Kingdom; 2009.
18.
McKeeverP, StevenB, MillerKL, et al.Home versus hospital breastfeeding support for newborns: A randomized controlled trial. Birth, 2002; 29(4):258–265; doi: 10.1046/j.1523-536x.2002.00200.x
19.
MaastrupR, RomAL, WalloeeS, et al.Improved exclusive breastfeeding rates in preterm infants after a neonatal nurse training program focusing on six breastfeeding-supportive clinical practices. PLoS One, 2021; 16(2):e0245273; doi: 10.1371/journal.pone.0245273
20.
JangEH, JuHO. Effects of an infant care education program for mothers of late-preterm infants on parenting confidence, breastfeeding rates, and infants' growth and readmission rates. Child Health Nur Res, 2020; 26(1):11–22; doi: 10.4094/chnr.2020.26.1.11
21.
JangGJ, KoS.Effects of a breastfeeding coaching program on growth and neonatal jaundice in late preterm infants in South Korea. Child Health Nurs Res, 2021; 27(4):377–384; doi: 10.4094/chnr.2021.27.4.377
22.
JangGJ, HongYR. Effects of a breastfeeding support program on the prevalence of exclusive breastfeeding and growth in late preterm infants. Child Health Nur Res, 2020; 26(1):90–97; doi: 10.4094/chnr.2020.26.1.90
23.
EstalellaI, MillanJS, TrinacadoMJ, et al.Evaluation of an intervention supporting breastfeeding among late-preterm infants during in-hospital stay. Women Birth, 2020; 33(1):e33–e38; doi: 10.1016/j.wombi.2018.11.003
24.
AbouelfettohAM, DowlingDA, DabashSA, et al.Cup versus bottle feeding for hospitalized late preterm infants in Egypt: A quasi-experimental study. Int Breastfeed J, 2008; 3(1):1–11; doi: 10.1186/1746-4358-3-27
25.
JangGJ.Influence of a breastfeeding coaching program on the breastfeeding rates and neonatal morbidity in late preterm infants. Child Health Nurs Res, 2020; 26(3):376–384; doi: 10.4094/chnr.2020.26.3.376
26.
DaniC, CiarciaM, MiselliF, et al.The management of late preterm infants: Effects of rooming-in assistance versus direct admission to neonatal care units. Eur J Pediatr, 2022; 181(4):1643–1649; doi: 10.1007/s00431-021-04337-z
27.
TomashekKM, Shapiro-MendozaC, WeissJ, et al.Early discharge among late preterm and term newborns and risk of neonatal morbidity. Semin Perinatol, 2006; 30(2):61–68; doi: 10.1053/j.semperi.2006.02.003
28.
EscobarGJ, GreeneJD, HulacP, et al.Rehospitalisation after birth hospitalisation: Patterns among infants of all gestations. Arch Dis Child, 2005; 90(2):125–131; doi: 10.1136/adc.2003.039974
29.
EscobarGJ, JoffeS, GardnerMN, et al.Rehospitalization in the first two weeks after discharge from the neonatal intensive care unit. Pediatrics, 1999; 104(1):e2; doi: 10.1542/peds.104.1.e2
30.
IsayamaT, O’ ReillyD, BeyeneJ, et al.Hospital care cost and resource use of early discharge of healthy late preterm and term singletons: A population-based cohort study and cost analysis. J Pediatr, 2020; 226(7):96–105; doi: 10.1016/j.jpeds.2020.06.060
31.
HolmKG, ClemensenJ, BrodsgaardA, et al.Growth and breastfeeding of preterm infants receiving neonatal tele-homecare compared to hospital-based care. J Neonatal Perinatal Med, 2019; 12(3):277–284; doi: 10.3233/NPM-18143
32.
GunnTR, ThompsonJM, JacksonH, et al.Does early hospital discharge with home support of families with preterm infants affect breastfeeding success? A randomized trial. Acta Paediatr, 2000; 89(11):1358–1363; doi: 10.1080/080352500300002570
33.
RayfieldS, OakleyL, QuigleyMA. Association between breastfeeding support and breastfeeding rates in the UK: A comparison of late preterm and term infants. BMJ Open, 2015; 5(11):e009144; doi: 10.1136/bmjopen-2015-009144
34.
RavnIH, SmithL, SmebyNA, et al.Effects of early mother-infant intervention on outcomes in mothers and moderately and late preterm infants at age 1 year: A randomized controlled trial. Infant Behav Dev, 2012; 35(1):36–47; doi: 10.1016/j.infbeh.2011.09.006
35.
EricsonJ, ErikssonM, Hellstrom-WestasL, et al.Proactive telephone support provided to breastfeeding mothers of preterm infants after discharge: A randomised controlled trial. Acta Paediatr, 2018; 107(5):791–798; doi: 10.1111/apa.14257
36.
MaastrupR, HansenBM, KronborgH, et al.Factors associated with exclusive breastfeeding of preterm infants: Results from a prospective national cohort study. PLoS One, 2014; 9(2):e89077; doi: 10.1371/journal.pone.0089077
37.
MattssonE, FunkquistE, WickstromM, et al.Healthy late preterm infants and supplementary artificial milk feeds: Effects on breast feeding and associated clinical parameters. Midwifery, 2015; 31(4):426–431; doi: 10.1016/j.midw.2014.12.004
38.
YilmazG, CaylanN, KaracanCD, et al.Effect of cup feeding and bottle feeding on breastfeeding in late preterm infants: A randomized controlled study. J Hum Lact, 2014; 30(2):174–179; doi: 10.1177/0890334413517940
39.
MöreliusE, OrtenstrandA, TheodorssonE, et al.A randomised trial of continuous skin-to-skin contact after preterm birth and the effects on salivary cortisol, parental stress, depression, and breastfeeding. Early Hum Dev, 2015; 91(1):63–70; doi: 10.1016/j.earlhumdev.2014.12.005
40.
Hake-BrooksSJ, AndersonGC. Kangaroo care and breastfeeding of mother-preterm infant dyads 0–18 months: A randomized, controlled trial. Neonatal Netw, 2008; 27(3):151–159; doi: 10.1891/0730-0832.27.3.151
41.
GregsonS, BlackerJ.Kangaroo care in pre-term or low birth weight babies in a postnatal ward. Br J Midwifery, 2011; 19(9):568–577; doi: 10.12968/bjom.2011.19.9.568
42.
ZhangB, DuanZ, ZhaoY, et al.Intermittent kangaroo mother care and the practice of breastfeeding late preterm infants: Results from four hospitals in different provinces of China. Int Breastfeed J, 2020; 15(1):1–9; doi: 10.1186/s13006-020-00309-5
43.
DemirciJR, BareS, CohenSM, et al.Feasibility and acceptability of two complementary and alternative therapies for perceived insufficient milk in mothers of late preterm and early term infants. Altern Complement Ther, 2016; 22(5):196–203; doi: 10.1089/act.2016.29072.jrd
44.
KeithDR, WeaverBS, VogelRL. The effect of music-based listening interventions on the volume, fat content, and caloric content of breast milk-produced by mothers of premature and critically ill infants. Adv Neonatal Care, 2012; 12(2):112–119; doi: 10.1097/ANC.0b013e31824d9842
45.
FeherSD, BergerLR, JohnsonJD, et al.Increasing breast milk production for premature infants with a relaxation/imagery audiotape. Pediatrics, 1989; 83(1):57–60; doi: 10.1542/peds.83.1.57
46.
Mohd ShukriNH, WellsJ, EatonS, et al.Randomized controlled trial investigating the effects of a breastfeeding relaxation intervention on maternal psychological state, breast milk outcomes, and infant behavior and growth. Am J Clin Nutr, 2019; 110(1):121–130; doi: 10.1093/ajcn/nqz033
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