Abstract
Objectives:
Evaluate a single institution’s rate of secondary hyperparathyroidism (SHPT) in bariatric surgery patients. Determine if bariatric surgery affects parathyroid hormone (PTH) and which patient-related factors may contribute to this relationship.
Methods:
Retrospective chart review of 69 bariatric surgery patients from 2018 to 2020. Patients were divided into normal versus high PTH (>77.8 pg/mL), based on preoperative values and separated by the type of procedure performed. t-Tests were used to compare the normal and high PTH cohorts.
Results:
Preoperative SHPT was seen in 25 patients (36.23%) and correlated with a higher BMI (kg/m2) than the normal preoperative PTH (NPTH) cohort (43.8 vs. 39.9, p = 0.01). SHPT patients saw a decrease in PTH from 104.2 pg/mL to 67.94 pg/mL at 9 months (p = 0.001). For those with SHPT, PTH levels returned to near preoperative values in the sleeve gastrectomy (SG) group but returned to normal levels for the Roux-en-Y gastric bypass (RYGB)T group (SG, 102.4–105.2 pg/mL; RYGB, 102.5–71.3 pg/mL), although data were limited for this subgroup analysis.
Conclusion:
SHPT is common in bariatric patients. Overall, patients initially maintain their preoperative PTH status over the first year after surgery, which should be considered in how they are monitored and managed with vitamin D supplementation.
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