Intragastric balloon (IGB) placement is one of the Food and Drug Administration (FDA) approved endoscopic bariatric therapies. Our aim was to identify the causes and the outcomes of this adverse event (AE).
Materials and Methods:
A literature search was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines using the terms “intragastric balloon” and “pancreatitis.”
Results:
Twenty-two articles with a total of 39 patients were found and analyzed, and 68.4% of patients were females. Median patient age was 30 years old (interquartile ranges [IQR] 24–36). At insertion of the IGB mean body mass index was 35.5 (±6.4). Mean IGB filling volume was 577.04 (±68.5) mL. Median time interval between IGB placement and pancreatitis was 61 (IQR 18.75–124) days. Computed tomography also clearly revealed compression of the pancreas by the IGB balloon in 66.6% of patients. 79.4% of patients were managed by IGB removal and 20.5% were managed conservatively. Regarding patients in whom IGB was removed, 93.5% of them underwent endoscopic removal, while only 6.4% underwent surgical removal (laparotomy).
Conclusions:
IGB-induced pancreatitis is an extremely rare AE that can occur while using the recommended balloon's fluid volume and placement duration.
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