Postoperative delirium (POD) is associated with long-term physical and cognitive impairment. Identification of eligible biomarkers is desirable. In this subanalysis of data collected during the prospective, observational Relevance of the Peripheral Cholinesterase-activity on Neurocognitive Dysfunctions in Surgical Patients (CESARO) study, we investigate the relevance of preoperative organ dysfunction on onset of POD.
Methods:
Patients (N = 98) undergoing laparoscopic bariatric surgery were screened for POD using the Nursing Delirium Screening Scale (Nu-DESC). All preoperatively assessed routine data, including laboratory results, were investigated for association with development of POD.
Results:
Twenty percent of patients suffered from POD of short duration. Obstructive sleep apnea and elevated blood urea nitrogen and low hematocrit levels were identified as predictors.
Conclusions:
POD incidence was similar to other studies, although our patients presented only marginal risk factors. The identified parameters might contribute to answering the question: Which are the biomarkers that correlate with the pathophysiologic process of delirium onset?. Clinical Trial Registration number: NCT01964274.
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