Prospective Randomized Trial on the Effects of Sevoflurane and Propofol on the Intraocular Pressure in Bariatric Surgery

Abstract

Background:

Intraocular pressure (IOP) alters during bariatric surgery according to body position, anesthetic agents, and intra-abdominal pressure. This study investigates the comparison of the effects of sevoflurane and total intravenous anesthesia (TIVA) procedure on IOP in bariatric surgery.

Methods:

Following local ethics committee approval, 55 American Society of Anesthesiologists I–III patients undergoing bariatric surgery were included. Patients were randomly allocated into two groups: Group P (n: 28) and Group S (n: 27). Sevoflurane (one minimum alveolar concentration) was administered to Group S, 5–10 mg/kg/h propofol infusion was performed in Group P, and 0.1–0.3 μg/kg/min remifentanil infusion was performed in both groups. Mean arterial pressure (MAP), heart rate (HR), and IOP were measured at the sitting position before the induction, supine before induction, after induction, 5 min after intubation, 10 min after pneumoperitoneum during head-down position, 5 min after terminating pneumoperitoneum, 5 min after extubation, and at postoperative 24th hour.

Results:

Demographic data, MAP, and HR were similar in groups. There were statistically significant decreases in IOP after induction of anesthesia in both groups (p < 0.05). In all time points, the IOP levels had no statistically significant differences between groups (p > 0.05).

Conclusions:

This study reveals that sevoflurane and TIVA procedures have similar effects on IOP in bariatric surgery.