Protein Carbonylation

Aldini G , Vistoli G , Regazzoni L , Benfatto MC , Bettinelli I , Carini M . Edaravone inhibits protein carbonylation by a direct carbonyl scavenging mechanism: Focus on reactivity, selectivity, and reaction mechanisms. Antioxid Redox Signal, 12:381–392. 2010.

Aldini G , Dalle–Donne I , Colombo R , Maffei Facino R , Milzani A , Carini M . Lipoxidation-derived reactive carbonyl species as potential drug targets in preventing protein carbonylation and related cellular dysfunction. Chem Med Chem, 1:1045–1058. 2006.

Aldini G , Dalle–Donne I , Facino RM , Milzani A , Carini M . Intervention strategies to inhibit protein carbonylation by lipoxidation-derived reactive carbonyls. Med Res Rev, 27:817–868. 2007.

Barreiro E , Hussain SNA . Protein carbonylation in skeletal muscles: Impact on function. Antioxid Redox Signal, 12:417–429. 2010.

Barreiro E , Gea J , Corominas JM , Hussain SN . Nitric oxide synthases and protein oxidation in the quadriceps femoris of patients with chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol, 29:771–778. 2003.

Barreiro E , Gea J , Di Falco M , Kriazhev L , James S , Hussain SN . Protein carbonyl formation in the diaphragm. Am J Respir Cell Mol Biol, 32:9–17. 2005.

Boyd–Kimball D , Sultana R , Poon HF , Lynn BC , Casamenti F , Pepeu G , Klein JB , Butterfield DA . Proteomic identification of proteins specifically oxidized by intracerebral injection of amyloid beta-peptide (1–42) into rat brain: implications for Alzheimer's disease. Neuroscience, 132:313–324. 2005.

Burcham PC , Fontaine F . Extensive protein carbonylation precedes acrolein-mediated cell death in mouse hepatocytes. J Biochem Mol Toxicol, 15:309–316. 2001.

Burcham PC , Raso A , Thompson CA . Intermediate filament carbonylation during acute acrolein toxicity in A549 lung cells: Functional consequences, chaperone redistribution, and protection by bisulfite. Antioxid Redox Signal, 12:337–347. 2010.

Butterfield DA , Perluigi M , Sultana R . Oxidative stress in Alzheimer's disease brain: New insights from redox proteomics. Eur J Pharmacol, 545:39–50. 2006.

Butterfield DA , Stadtman ER . Protein oxidation processes in aging brain. Advances in Cell Aging and Gerontology Volume 2. Timiras PS , Bittar EE . Greenwich, CT: JAI Press, 1997; 161–191.

Castegna A , Aksenov M , Aksenova M , Thongboonkerd V , Klein JB , Pierce WM , Booze R , Markesbery WR , Butterfield DA . Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: Creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1. Free Radic Biol Med, 33:562–571. 2002.

Colombo G , Aldini G , Orioli M , Giustarini D , Gornati R , Rossi R , Colombo R , Carini M , Milzani A , Dalle–Donne I . Water-soluble α,β-unsaturated aldehydes of cigarette smoke induce carbonylation of human serum albumin. Antioxid Redox Signal, 12:349–364. 2010.

Grimsrud PA , Xie H , Griffin TJ , Bernlohr DA . Oxidative stress and covalent modification of protein with bioactive aldehydes. J Biol Chem, 283:21837–21841. 2008.

Levine RL . Carbonyl modified proteins in cellular regulation, aging, and disease. Free Radic Biol Med, 32:790–796. 2002.

Levine RL , Williams JA , Stadtman ER , Shacter E . Carbonyl assays for determination of oxidatively modified proteins. Methods Enzymol, 233:346–357. 1994.

Levine RL , Wehr N , Williams JA , Stadtman ER , Shacter E . Determination of carbonyl groups in oxidized proteins. Methods Mol Biol, 99:15–24. 2000.

Marin–Corral J , Fontes CC , Pascual–Guardia S , Sanchez F , Olivan M , Argilés JM , Busquets S , López–Soriano FJ , Barreiro E . Redox balance and carbonylated proteins in limb and heart muscles of cachectic rats. Antioxid Redox Signal, 12:365–380. 2010.

Moskovitz J , Oien DB . Protein carbonyl and the methionine sulfoxide reductase system. Antioxid Redox Signal, 12:405–415. 2010.

Negre–Salvayre A , Coatrieux C , Ingueneau C , Salvayre R . Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors. Br J Pharmacol, 153:6–20. 2008.

Sayre LM , Lin D , Yuan Q , Zhu X , Tang X . Protein adducts generated from products of lipid oxidation: focus on HNE and one. Drug Metab Rev, 38:651–675. 2006.

Shacter E , Williams JA , Lim M , Levine RL . Differential susceptibility of plasma proteins to oxidative modification: examination by western blot immunoassay. Free Radic Biol Med, 17:429–437. 1994.

Stadtman ER , Levine RL . Protein oxidation. Ann NY Acad Sci, 899:191–208. 2000.

Stadtman ER , Levine RL . Chemical modification of proteins by reactive oxygen species. Redox Proteomics: From Protein Modifications to Cellular Dysfunction and Diseases. Dalle–Donne I , Scaloni A , Butterfield DA . Hoboken NJ: John Wiley & Sons, 2006; 3–23.

Sultana R , Perluigi M , Newman SF , Pierce WM , Cini C , Coccia R , Butterfield DA . Redox proteomic analysis of carbonylated brain proteins in mild cognitive impairment and early Alzheimer's disease. Antioxid Redox Signal, 12:325–336. 2010.

Wong CM , Cheema AK , Zhang L , Suzuki YJ . Protein carbonylation as a novel mechanism in redox signaling. Circ Res, 102:310–318. 2008.

Wong CM , Marcocci L , Liu L , Suzuki YJ . Cell signaling by protein carbonylation and decarbonylation. Antioxid Redox Signal, 12:393–404. 2010.