Corrigendum for Pedone E,Limauro D,and Bartolucci S. The Machinery for Oxidative Protein Folding in Thermophiles. Antioxid Redox Signal 10:157–169,2008

Amegbey GY , Monzavi H , Habibi-Nazhad B , Bhattacharyya S , Wishart DS . Structural and functional characterization of a thioredoxin-like protein (Mt0807) from Methanobacterium thermoautotrophicum. Biochemistry, 42:8001–8010. 2003.

Arcari P , Fasullo L , Masullo M , Catanzano F , Bocchini V . An NAD(P)H oxidase isolated from the archaeon Sulfolobus solfataricus is not homologous with another NADH oxidase present in the same microorganism: Biochemical characterization of the enzyme and cloning of the encoding gene. J Biol Chem, 275:895–900. 2000.

Bartolucci S , Guagliardi A , Pedone E , De Pascale D , Cannio R , Camardella L , Rossi M , Nicastro G , de Chiara C , Facci P , Mascetti G , Nicolini C . Thioredoxin from Bacillus acidocaldarius: Characterization, high-level expression in Escherichia coli, and molecular modelling. Biochem J, 328:277–285. 1997.

Bartolucci S , de Pascale D , Rossi M . Protein disulfide oxidoreductase from Pyrococcus furiosus: biochemical properties. Methods Enzymol, 334:62–73. 2001.

Bartolucci S , De Simone G , Galdiero S , Improta R , Menchise V , Pedone C , Pedone E , Saviano M . An integrated structural and computational study on the thermostability of two thioredoxin mutants from Alicyclobacillus acidocaldarius. J Bacteriol, 185:4285–4289. 2003.

Beeby M , O'Connor BD , Ryttersgaard C , Boutz DR , Perry LJ , Yeates TO . The genomics of disulfide bonding and protein stabilization in thermophiles. PLoS Biol, 3:1549–1558. 2005.

Bhattacharyya S , Habibi-Nazhad B , Amegbey G , Slupsky CM , Yee A , Arrowsmith C , Wishart DS . Identification of a novel archaebacterial thioredoxin: Determination of function through structure. Biochemistry, 41:4760–4770. 2002.

Bjornstedt M , Hamberg M , Kumar S , Xue J , Holmgren A . Human thioredoxin reductase directly reduces lipid hydroperoxides by NADPH and selenocystine strongly stimulates the reaction via catalytically generated selenols. J Biol Chem, 270:11761–11764. 1995.

Bjornstedt M , Kumar S , Bjorkhem L , Spyrou G , Holmgren A . Selenium and the thioredoxin and glutaredoxin systems. Biomed Environ Sci, 10:271–279. 1997.

Buettner C , Harney JW , Berry MJ . The Caenorhabditis elegans homologue of thioredoxin reductase contains a selenocysteine insertion sequence (SECIS) element that differs from mammalian SECIS elements but directs selenocysteine incorporation. J Biol Chem, 274:21598–21602. 1999.

Cannio R , Fiorentino G , Carpinelli P , Rossi M , Bartolucci S . Cloning and overexpression in Escherichia coli of the genes encoding NAD-dependent alcohol dehydrogenase from two Sulfolobus species. J Bacteriol, 178:301–305. 1996.

Carvalho AP , Fernandes PA , Ramos MJ . Similarities and differences in the thioredoxin superfamily. Prog Biophys Mol Biol, 91:229–248. 2006.

Chae HZ , Chung SJ , Rhee SG . Thioredoxin-dependent peroxide reductase from yeast. J Biol Chem, 269:27670–27678. 1994.

D'Ambrosio K , De Simone G , Pedone E , Rossi M , Bartolucci S , Pedone C . Crystallization and preliminary X-ray diffraction studies of a protein disulfide oxidoreductase from Aquifex aeolicus. Acta Crystallogr Sect D, 60:2076–2077. 2004.

D'Ambrosio K , De Simone G , Pedone E , Rossi M , Bartolucci S , Pedone C . Crystallization and preliminary X-ray diffraction studies of a protein disulfide oxidoreductase from Aeropyrum pernix K1. Acta Crystallogr Sect F, 61:335–336. 2005.

D'Ambrosio K , Pedone E , Langella E , De Simone G , Rossi M , Pedone C , Bartolucci S . A novel member of the protein disulfide oxidoreductase family from Aeropyrum pernix K1: Structure, function and electrostatics. J Mol Biol, 362:743–752. 2006.

D'Ambrosio K , Limauro D , Pedone E , Galdi I , Pedone C , Bartolucci S , De Simone G . Insights into the catalytic mechanism of the Bcp family: Functional and structural analysis of Bcp1 from Sulfolobus solfataricus. Proteins, 76:995–1006. 2009.

Digilio FA , Morra R , Pedone E , Bartolucci S , Rossi M . High-level expression of Aliciclobacillus acidocaldarius thioredoxin in Pichia pastoris and Bacillus subtilis. Protein Expr Purif, 30:179–184. 2003.

Dijkstra K , Karvonen P , Pirneskoski A , Koivunen P , Kivirikko KI , Darby NJ , van Straaten M , Scheek RM , Kemmink J . Assignment of 1H, 13C and 15N resonances of the a_ domain of protein disulfide isomerase. J Biomol NMR, 14:195–196. 1999.

Ferrari DM , Söling HD . The protein disulphide-isomerase family: Unraveling a string of folds. Biochem J, 339:1–10. 1999.

Freedman RB. Novel disulfide oxidoreductase in search of a function. Nat Struct Biol, 5:531–532. 1998.

Fuchs JA. Dolphin D , Poulsen R , Avramovic O. Glutathione: Chemical, Biochemical, and Medical Aspects. New York: John Wiley and Sons, 1989; Part B:551.

Ghisla S , Massey V . Mechanisms of flavoprotein catalyzed reactions. Eur J Biochem, 181:1–17. 1989.

Gladyshev VN , Jeang KT , Stadtman TC . Selenocysteine, identified as the penultimate C-terminal residue in human T-cell thioredoxin reductase, corresponds to TGA in the human placental gene. Proc Natl Acad Sci USA, 93:6146–6151. 1996.

Gleason FK , Holmgren A . Thioredoxin and related proteins in procaryotes. FEMS Microbiol Rev, 4:271–297. 1988.

Grauschopf U , Winther JR , Korber P , Zander T , Dallinger P , Bardwell JC . Why is DsbA such an oxidizing disulfide catalyst? Cell, 83:947–955. 1995.

Gromer S , Merkle H , Schirmer RH , Becker K . Human placenta thioredoxin reductase: Preparation and inhibitor studies. Methods Enzymol, 347:382–394. 2002.

Gruber CW , Cemazar M , Heras B , Martin JL , Craik DJ . Protein disulfide isomerase: The structure of oxidative folding. Trends Biochem Sci, 31:455–464. 2006.

Guagliardi A , Cerchia L , De Rosa M , Rossi M , Bartolucci S . Isolation of a thermostable enzyme catalyzing disulfide bond formation from the archaebacterium Sulfolobus solfataricus. FEBS Lett, 303:27–30. 1992.

Guagliardi A , Nobile V , Bartolucci S , Rossi M . Isolation of a thioredoxin from the extreme thermophilic archaebacterium Sulfolobus solfataricus. Int J Biochem, 26:375–380. 1994.

Guagliardi A , Cerchia L , Camardella L , Rossi M , Bartolucci S . DBF(disulfide bond forming) from the hyperthermophilic archaebacterium Sulfolobus solfataricus behaves as a molecular chaperone. Biocatalysis Biotransform, 11:181–190. 1994.

Guagliardi A , de Pascale D , Cannio R , Nobile V , Bartolucci S , Rossi M . The purification, cloning, and high level expression of a glutaredoxin-like protein from the hyperthermophilic Archaeon Pyrococcus furiosus. J Biol Chem, 270:5748–5755. 1995.

Holmgren A. Thioredoxin. Annu Rev Biochem, 54:237–271. 1985.

Holmgren A. Thioredoxin and glutaredoxin: Small multi-functional redox proteins with active-site disulphide bonds. Biochem Soc Trans, 16:95–96. 1988.

Holmgren A , Bjornstedt M . Thioredoxin and thioredoxin reductase. Methods Enzymol, 252:199–208. 1995.

Holmgren A , Johansson C , Berndt C , Lonn ME , Hudemann C , Lillig CH . Thiol redox control via thioredoxin and glutaredoxin systems. Biochem Soc Trans, 33:1375–1377. 2005.

Jeon SJ , Ishikawa K . Identification and characterization of thioredoxin and thioredoxin reductase from Aeropyrum pernix K1. Eur J Biochem, 269:5423–5430. 2002.

Jeon SJ , Ishikawa K . Characterization of novel hexadecameric thioredoxin peroxidase from Aeropyrum pernix K1. J Biol Chem, 278:24174–24180. 2003.

Kashima Y , Ishikawa K . Alkyl hydroperoxide reductase dependent on thioredoxin-like protein from Pyrococcus horikoshii. J Biochem (Tokyo), 134:25–29. 2003.

Kashima Y , Ishikawa K . A hyperthermostable novel proteindisulfide oxidoreductase is reduced by thioredoxin reductase from hyperthermophilic archaeon Pyrococcus horikoshii. Arch Biochem Biophys, 418:179–185. 2003.

Kawakami R , Sakuraba H , Kamohara S , Goda S , Kawarabayasi Y , Ohshima T . Oxidative stress response in an anaerobic hyperthermophilic archaeon: Presence of a functional peroxiredoxin in Pyrococcus horikoshii. J Biochem (Tokyo)., 136:541–547. 2004.

Kemmink J , Darby NJ , Dijkstra K , Nilges M , Creighton TE . Structure determination of the N-terminal thioredoxin-like domain of protein disulfide isomerase using multidimensional heteronuclear 13C/15N NMR spectroscopy. Biochemistry, 35:7684–7691. 1996.

Kemmink J , Dijkstra K , Mariani M , Scheek RM , Penka E , Nilges M , Darby NJ . The structure in solution of the b domain of protein disulfide isomerase. J Biomol NMR, 13:357–368. 1999.

Kortemme T , Darby NJ , Creighton TE . Electrostatic interactions in the active site of the N-terminal thioredoxin-like domain of protein disulfide isomerase. Biochemistry, 35:14503–14511. 1996.

Ladenstein R , Ren B . Protein disulfides and protein disulfide oxidoreductases in hyperthermophiles. FEBS J, 273:4170–4185. 2006.

Lappi A , Lensink M , Alanen H , Salo K , Lobell M , Juffer A , Ruddock L . A conserved arginine plays a role in the catalytic cycle of the protein disulphide isomerases. J Mol Biol, 335:283–295. 2004.

Lee DY , Ahn BY , Kim KS . A thioredoxin from the hyperthermophilic archaeon Methanococcus jannaschii has a glutaredoxin-like fold but thioredoxin-like activities. Biochemistry, 39:6652–6659. 2000.

Lemaire SD , Miginiac-Maslow M . The thioredoxin superfamily in Chlamydomonas reinhardtii. Photosynth Res, 82:203–220. 2004.

Leone M , Di Lello P , Ohlenschlager O , Pedone EM , Bartolucci S , Rossi M , Di Blasio B , Pedone C , Saviano M , Isernia C , Fattorusso R . Solution structure and backbone dynamics of the K18G/R82E Alicyclobacillus acidocaldarius thioredoxin mutant: A molecular analysis of its reduced thermal stability. Biochemistry, 43:6043–6058. 2004.

Li K , Pasternak C , Klug G . Expression of the trxA gene for thioredoxin 1 in Rhodobacter sphaeroides during oxidative stress. Arch Microbiol, 180:484–489. 2003.

Limauro D , Fiorentino G , Bartolucci S. Farina B , Faraone Mennella MR. How Sulfolobus responds to enviromental stress. Biochemistry and Molecular Biology in the Thermophilic Archaeon S. solfataricus”, Chapter 6:105–130. 2004. Research Signpost T.C. 37/661 (2) Fort P.O., Trivandrum-695 023, Kerala, India.

Limauro D , Pedone E , Pirone L , Bartolucci S . Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress. FEBS J, 273:721–731. 2006.

Limauro D , Pedone E , Galdi I , Bartolucci S. Peroxiredoxins as cellular guardians in Sulfolobus solfataricus: Characterization of Bcp1, Bcp3 and Bcp4. FEBS J, 275:2067–2077. 2008.

Limauro D , Saviano M , Galdi I , Rossi M , Bartolucci S , Pedone E . Sulfolobus solfataricus protein disulphide oxidoreductase: Insight into the roles of its redox sites. Protein Eng Des Sel, 22:19–26. 2009.

Mallick P , Boutz DR , Eisenberg D , Yeates T O . Genomic evidence that the intracellular proteins of archaeal microbes contain disulfide bonds. Proc Natl Acad Sci USA, 99:9679–9684. 2002.

Martin JL , Bardwell JC , Kuriyan J . Crystal structure of the DsbA protein required for disulphide bond formation in vivo. Nature, 365:464–468. 1993.

Martin JL. Thioredoxin: A fold for all reasons. Structure, 3:245–250. 1995.

McFarlan SC , Terrell CA , Hogenkamp HP . The purification, characterization, and primary structure of a small redox protein from Methanobacterium thermoautotrophicum, an archaebacterium. J Biol Chem, 267:10561–10569. 1992.

Meister A. Glutathione metabolism and its selective modification. J Biol Chem, 263:17205–17208. 1988.

Miranda-Vizuete A , Damdimopoulos AE , Gustafsson J , Spyrou G . Cloning, expression, and characterization of a novel Escherichia coli thioredoxin. J Biol Chem, 272:30841–30847. 1997.

Mittard V , Blackledge MJ , Stein M , Jacquot JP , Marion D , Lancelin JM . NMR solution structure of an oxidised thioredoxin h from the eukaryotic green alga Chlamydomonas reinhardtii. Eur J Biochem, 243:374–383. 1997.

Mizohata E , Sakai H , Fusatomi E , Terada T , Murayama K , Shirouzu M , Yokoyama S . Crystal structure of an archaeal peroxiredoxin from the aerobic hyperthermophilic crenarchaeon Aeropyrum pernix K1. J Mol Biol, 354:317–329. 2005.

Moore EC , Reichard P , Thelander L . Enzymatic synthesis of deoxyribonucleotides.V. Purification and properties of thioredoxin reductase from Escherichia coli B. J Biol Chem, 239:3445–3452. 1964.

Moutevelis E , Warwickwe J . Prediction of pKa and redox properties in the thioredoxin superfamily. Protein Sci, 13:2744–2752. 2004.

Nicastro G , De Chiara C , Pedone E , Tatò M , Rossi M , Bartolucci S . NMR solution structure of a novel thioredoxin from Bacillus acidocaldarius possible determinants of protein stability. Eur J Biochem, 267:403–413. 2000.

Pedone EM , Bartolucci S , Rossi M , Saviano M . Computational analysis of the thermal stability in thioredoxins: A molecular dynamics approach. J Biomol Struct Dyn, 16:437–446. 1998.

Pedone E , Cannio R , Saviano M , Rossi M , Bartolucci S . Prediction and experimental testing of the Bacillus acidocaldarius thioredoxin stability. Biochem J, 339:309–317. 1999.

Pedone E , Saviano M , Rossi M , Bartolucci S . A single point mutation (Glu85Arg) increases the stability of the thioredoxin from Escherichia coli. Protein Eng, 14:255–260. 2001.

Pedone E , Bartolucci S , Rossi M , Pierfederici FM , Scirè A , Cacciamani T , Tanfani F . Structural and thermal stability analysis of Escherichia coli and Alicyclobacillus acidocaldarius thioredoxin revealed a molten globule-like state in thermal denaturation pathway of the proteins: A spectroscopic infrared study. Biochem J, 373:875–883. 2003.

Pedone E , Bartolucci S , Fiorentino G . Sensing and adapting to environmental stress: The archaeal tactic. Front Biosci, 9:2909–2926. 2004.

Pedone E , Ren B , Ladenstein R , Rossi M , Bartolucci S . Functional properties of the protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus: A member of a novel protein family related to protein disulfide-isomerase. Eur J Biochem, 271:3437–3448. 2004.

Pedone E , Saviano M , Bartolucci S , Rossi M , Ausili A , Scirè A , Bertoli E , Tanfani F . Temperature-, SDS-, and pH-induced conformational changes in protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus: A dynamic simulation and Fourier transform infrared spectroscopic study. J Proteome Res, 4:1972–1980. 2005.

Pedone E , D'Ambrosio K , De Simone G , Rossi M , Pedone C , Bartolucci S . Insights on a new PDI-like family: Structural and functional analysis of a protein disulfide oxidoreductase from the bacterium Aquifex aeolicus. J Mol Biol, 356:155–164. 2006.

Pedone E , Limauro D , D'Alterio R , Rossi M , Bartolucci S . Characterization of a multifunctional protein disulfide oxidoreductase from Sulfolobus solfataricus. FEBS J, 273:5407–5420. 2006.

Pedone E , Limauro D , Bartolucci S . The machinery for oxidative protein folding in thermophiles. Antioxid Redox Signal, 10:157–169. 2008.

Prieto-Alamo MJ , Jurado J , Gallardo-Madueno R , Monje-Casas F , Holmgren A , Pueyo C . Transcriptional regulation of glutaredoxin and thioredoxin pathways and related enzymes in response to oxidative stress. J Biol Chem, 275:13398–13405. 2000.

Prinz WA , Aslund F , Holmgren A , Beckwith J . The role of the thioredoxin and glutaredoxin pathways in reducing protein disulfide bonds in the Escherichia coli cytoplasm. J Biol Chem, 272:15661–15667. 1997.

Prongay AJ , Engelke DR , Williams CH. Jr . Characterization of two active site mutations of thioredoxin reductase from Escherichia coli. J Biol Chem, 264:2656–2664. 1989.

Raia CA , Guagliardi A , D'Auria S , Bartolucci S , De Rosa M , Rossi M . Characterization of redox proteins from extreme thermophilic archaebacteria: studies on alcohol dehydrogenase and thioredoxins. Biosensors Bioelectron, 10:135–140. 1995.

Rehse PH , Kumei M , Tahirov TH . Compact reduced thioredoxin structure from the thermophilic bacteria Thermus thermophilus. Proteins, 61:1032–1037. 2005.

Ren B , Tibbelin G , Rossi M , Bartolucci S , Ladenstein R . Crystallization and preliminary X-ray structure analysis of a hyperthermostable thioltransferase from the archaeon Pyrococcus furiosus. J Struct Biol, 119:1–5. 1997.

Ren B , Tibbelin G , de Pascale D , Rossi M , Bartolucci S , Ladenstein R . A protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus contains two thioredoxin fold units. Nat Struct Biol, 5:602–611. 1998.

Ren B , Ladenstein R . Protein disulfide oxidoreductase from Pyrococcus furiosus: Structural properties. Methods Enzymol, 334:74–88. 2001

Reynolds CM , Meyer J , Poole LB . A NADH-dependent bacterial thioredoxin reductase-like protein in conjunction with a glutaredoxin homologue form a unique peroxiredoxin (AhpC) reducing system in Clostridium pasteurianum. Biochemistry, 41:1990–2001. 2002.

Rigobello MP , Scutari G , Folda A , Bindoli A . Mitochondrial thioredoxin reductase inhibition by gold(I) compounds and concurrent stimulation of permeability transition and release of cytochrome c. Biochem Pharmacol, 67:689–696. 2004.

Ritz D , Pate H , Doan B , Zheng M , Åslund F , Storz G , Beckwith J . Thioredoxin 2 is involved in the oxidative stress response in Escherichia coli. J Biol Chem, 275:2505–2512. 2000.

Rossmann R , Stern D , Loferer H , Jacobi A , Glockshuber R , Hennecke H . Replacement of Pro109 by His in TlpA, a thioredoxin-like protein from Bradyrhizobium japonicum, alters its redox properties but not its in vivo functions. FEBS Lett, 406:249–254. 1997.

Rouhier N , Gelhaye E , Sautiere PE , Brun A , Laurent P , Tagu D , Gerard J , de Fay E , Meyer Y , Jacquot JP . Isolation and characterization of a new peroxiredoxin from poplar sieve tubes that use either glutaredoxin or thioredoxin as a proton donor. Plant Physiol, 127:1299–1309. 2001.

Ruddock LW , Hirst TR , Feedman RB . pH-dependence of the dithiol-oxidizing activity of DsbA (a periplasmic protein thiol:disulphide oxidoreductase) and protein disulphide-isomerase: Studies with a novel simple peptide substrate. Biochem J, 315:1000–1005. 1995.

Ruocco MR , Ruggiero A , Masullo L , Arcari P , Masullo M . A 35 kDa NAD(P)H oxidase previously isolated from the archaeon Sulfolobus solfataricus is instead a thioredoxin reductase. Biochimie, 86:883–892. 2004.

Saarinen M , Gleason FK , Eklund H . Crystal structure of thioredoxin-2 from Anabaena. Structure, 3:1097–1108. 1995.

She Q , Singh RK , Confalonieri F , Zivanovic Y , Allard G , Awayez M J , Chan-Weiher CC , Clausen IG , Curtis BA , De Moors A. , Erauso G , Fletcher C , Gordon PM , Heikamp-de Jong I , Jeffries AC , Kozera CJ , Medina N , Peng X , Thi-Ngoc HP , Redder P , Schenk ME , Theriault C , Tolstrup N , Charlebois RL , Doolittle WF , Duguet M , Gaasterland T , Garrett RA , Ragan MA , Sensen CW , Van der Oost J . The complete genome of the crenarchaeon Sulfolobus solfataricus P2. Proc Natl Acad Sci USA, 8:7835–7840. 2001.

Silva G , LeGall J , Xavier AV , Teixeira M , Rodrigues-Pousada C . Molecular characterization of Desulfovibrio gigas neelaredoxin, a protein involved in oxygen detoxification in anaerobes. J Bacteriol, 183:4413–4420. 2001.

Song J , Quan H , Wang C . Dependence of anti-chaperone activity of protein disulphide isomerase on its chaperone activity. Biochem J, 328:841–846. 1997.

Tamura T , Stadtman TC . A new selenoprotein from human lung adenocarcinoma cells: Purification, properties, and thioredoxin reductase activity. Proc Natl Acad Sci USA, 3:1006–1011. 1996.

Tian G , Xiang S , Noiva R , Lennarz WJ , Schindelin H . The crystal structure of yeast protein disulfide isomerase suggests cooperativity between its active sites. Cell, 124:61–73. 2006.

Wang PF , Arscott LD , Gilberger TW , Muller S , Williams CH Jr. Thioredoxin reductase from Plasmodium falciparum: Evidence for interaction between the C-terminal cysteine residues and the active site disulfide-dithiol. Biochemistry, 38:3187–3196. 1999.

Williams CH Jr. Mechanism and structure of thioredoxin reductase from Escherichia coli. FASEB J, 9:1267–1276. 1995.

Wilkinson B , Gilbert HF . Protein disulfide isomerase. Biochim Biophys Acta, 1699:35–44. 2004.

Wood ZA , Schroder E , Robin Harris J , Poole LB . Structure, mechanism and regulation of peroxiredoxins. Trends Biochem Sci, 28:32–40. 2003.

Wunderlich M , Glockshuber R . Redox properties of protein disulfide isomerase (DsbA) from Escherichia coli. Protein Sci, 2:717–726. 1993.

Zillig W , Palm P , Reiter WD , Gropp F , Puhler G , Klenk HP . Comparative evaluation of gene expression in archaebacteria. Eur J Biochem, 173:473–482. 1988.