Bilateral Leg Swelling as the Initial and Predominant Presentation of HIV and Associated Pulmonary Arterial Hypertension

Abstract

Although mortality from HIV has decreased over the last several years as a result of effective antiretroviral therapy, the infection continues to pose significant morbidity. Pulmonary arterial hypertension (PAH), for instance, has been reported to occur in the setting of established HIV infection on only rare occasions and carries a universally poor prognosis. The current case report is unique in describing a previously well patient who presents initially with complaints of debilitating leg swelling and is subsequently diagnosed with HIV and associated PAH.