Abstract
This issue of Androgens focuses on the timely topic of testosterone and sexual function.
Aristotle first documented the effects of castration, then in 1889 Brown-Sequard self-administered injections of testicular extract and reported reversal of the aging process, and in 1939 Butenandt and Ruzicka won the Nobel Prize for the discovery and synthesis of testosterone. Since then, testosterone and hypogonadism have become an integral part of most urology and men's health practices with more and more men seeking treatment.
Similarly, sexual dysfunction issues are among the most bothersome conditions men encounter, often leading to considerable personal, psychological, and relationship issues. There is now a considerable body of evidence suggesting intimate relationships between circulating testosterone levels and sexual function. There is also a growing body of evidence suggesting that testosterone supplementation in hypogonadal men may lead to improvements in various aspects of sexual performance.
In this collection of studies, we sought to better define that relationship. To that end, we have invited world leaders in various fields of urology to help us better understand how testosterone is responsible for the development and maturity of male sexual organs in children to the roles of testosterone in regulating libido, ejaculations, erections, and Peyronie's disease. Controversial topics will also be addressed such as the impact of varicocele treatment on testosterone levels, as well as the risks and benefits of testosterone therapy in men after prostate cancer surgery or undergoing androgen deprivation therapy.
We are honored to have been invited by Drs. Abdulmaged M. Traish and Abraham Morgentaler, and the rest of the androgens team to put together this exciting edition on testosterone and sexual function. The controversies and advancements presented will undoubtedly lead to clinical progress for our many patients who suffer from these conditions.