Sage Journals: Discover world-class research

Abstract

Since the first characterization of SIVsun (L14 strain) from a sun-tailed monkey (Cercopithecus solatus) in Gabon in 1999, no further information exists about the evolutionary history and geographic distribution of this lentivirus. Here, we report the full-length molecular characterization of a second SIVsun virus (SIVsunK08) naturally infecting a wild-caught sun-tailed monkey. The SIVsunK08 strain was most closely related to SIVsunL14 and clustered with members of the SIVmnd-1/SIVlhoest group. SIVsunK08 shared identical functional motifs in the LTR, Gag and Env proteins with SIVsunL14. Our data indicate that C. solatus is naturally infected with a monophyletic SIVsun strain.

Get full access to this article

View all access options for this article.

References

Ahuka-Mundeke

, Liegeois

, Ayouba

et al. Full-length genome sequence of a simian immunodeficiency virus infecting a captive Agile Mangabey (Cercocebus agilis) is closely related to SIVrcm infecting wild red-capped mangabeys (Cercocebus torquatus) in Cameroon. J Gen Virol, 2010; 10:2959–2964.

Goldberg

, Sintasath

, Chapman

et al. Coinfection of Ugandan red colobus (Procolobus [Piliocolobus] rufomitratus tephrosceles) with novel, divergent delta-, lenti-, and spumaretroviruses. J Virol, 2009; 83,21:11318–11329.

Liegeois

, Lafay

, Formenty

et al. Full-length genome characterization of a novel simian immunodeficiency virus lineage (SIVolc) from olive Colobus (Procolobus verus) and new SIVwrcPbb strains from Western Red Colobus (Piliocolobus badius badius) from the Tai Forest in Ivory Coast. J Virol, 2009; 83,1:428–439.

Peeters

, Courgnaud

, Abela

et al. Risk to human health from a plethora of simian immunodeficiency viruses in primate bushmeat. Emerg Infect Dis, 2002; 8,5:451–457.

Worobey

, Telfer

, Souquiere

et al. Island biogeography reveals the deep history of SIV. Science, 2010; 329,5998:1487.

Hahn

, Shaw

, De Cock

et al. AIDS as a zoonosis: Scientific and public health implications. Science, 2000; 287,5453:607–614.

Takehisa

, Harada

, Ndembi

et al. Natural infection of wild-born mandrills (Mandrillus sphinx) with two different types of simian immunodeficiency virus. AIDS Res Hum Retroviruses, 2001; 17,12:1143–1154.

Aghokeng

, Bailes

, Loul

et al. Full-length sequence analysis of SIVmus in wild populations of mustached monkeys (Cercopithecus cephus) from Cameroon provides evidence for two co-circulating SIVmus lineages. Virology, 2007; 360,2:407–418.

Gautier-Hion

, Colyn

, Gauthier

J-P

. Histoire naturelle des primates d'Afrique centrale. Ecofac, 1999.

10.

Beer

, Bailes

, Goeken

et al. Simian immunodeficiency virus (SIV) from sun-tailed monkeys (Cercopithecus solatus): Evidence for host-dependent evolution of SIV within the C. lhoesti superspecies. J Virol, 1999; 73,9:7734–7744.

11.

Hirsch

, Campbell

, Bailes

et al. Characterization of a novel simian immunodeficiency virus (SIV) from L'Hoest monkeys (Cercopithecus l'hoesti): Implications for the origins of SIVmnd and other primate lentiviruses. J Virol, 1999; 73,2:1036–1045.

12.

Tamura

, Dudley

, Nei

, Kumar

. MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol, 2007; 24,8:1596–1599.

13.

Dimmic

, Rest

, Mindell

, Goldstein

. rtREV: An amino acid substitution matrix for inference of retrovirus and reverse transcriptase phylogeny. J Mol Evol, 2002; 55,1:65–73.

14.

Yang

. Maximum likelihood phylogenetic estimation from DNA sequences with variable rates over sites: Approximate methods. J Mol Evol, 1994; 39,3:306–314.

15.

Leclerq

, Motsch

, Gonzalez

. New evaluation of the geographical distribution of Gabon's Sun-tailed guenon (Cercopithecus solatus) Abstract of the 23th Science Meeting of the Société Francophone de Primatologie, Aix en Provence, October 2010.

Supplementary Material

Please find the following supplemental material available below.

For Open Access articles published under a Creative Commons License, all supplemental material carries the same license as the article it is associated with.

For non-Open Access articles published, all supplemental material carries a non-exclusive license, and permission requests for re-use of supplemental material or any part of supplemental material shall be sent directly to the copyright owner as specified in the copyright notice associated with the article.

0.00 MB

0.02 MB

Full-Length Genome Sequence of a Simian Immunodeficiency Virus from a Wild-Captured Sun-Tailed Monkey in Gabon Provides Evidence for a Species-Specific Monophyletic SIVsun Lineage

Abstract

Get full access to this article

References

Supplementary Material