National Human Genome Research Institute, National Institutes of Health. The Human Genome Project Completion: Frequently Asked Questions. Online document at: www.genome.gov/11006943 Accessed May9, 2015.
2.
EzkurdiaI, JuanD, RodriguezJM, et al.Multiple evidence strands suggest that there may be as few as 19,000 human protein-coding genes. Hum Mol Genet, 2014; 23:5866–5878.
3.
HoDH. Historical perspective of transgenerational epigenetics. In: TollefsbolT, ed. Transgenerational Epigenetics: Evidence and Debate. London: Academic Press, 2014:17–23.
4.
CareyN. The Epigenetics Revolution: How Modern Biology Is Rewriting Our Understanding of Genetics, Disease, and Inheritance. New York: Columbia University Press, 2012.
5.
National Institutes of Health. NIH-Supported Researchers Map Epigenome of More than 100 Tissue and Cell Types. February18, 2015. Online document at: www.nih.gov/news/health/feb2015/niehs-18.htm Accessed May21, 2015.
6.
KennedyBK, BergerSl, BrunetA, et al.Geroscience: Linking aging to chronic disease. Cell, 2014; 159:709–713.
7.
FrancisRC. Epigenetics: The Ultimate Mystery of Inheritance. New York: W.W. Norton, 2011.
8.
VersmissenJ, van LennepJR, SijbrandsEJG. Clinical aspects of transgenerational epigenetics. In: TollefsbolT, ed. Transgenerational Epigenetics: Evidence and Debate. London: Academic Press, 2014:357–367.
9.
HiuraH, OkaeH, ChibaH, et al.Imprinting methylation errors in ART. Reprod Med Biol, 2014; 13:193–202.
10.
LópezAJ, WoodMA. Role of nucleosome remodeling in neurodevelopmental and intellectual disability disorders. Front Behav Neurosci, 2015; 9:10–0.
11.
WongCC, MeaburnEL, RonaldA, et al.Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits. Mol Psychiatry, 2014; 19:495–503.
12.
TobiEW, SliekerRC, SteinAD, et al.Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome. Int J Epidemiol, 2015; May5:e-pub ahead of print.
13.
KellermanNP. Epigenetic transmission of Holocaust trauma: Can nightmares be inherited?. Isr J Psychiatry Relat Sci, 2013; 50:33–39.
14.
YahyaviST, ZarghamiM, MarwahU. A review on the evidence of transgenerational transmission of posttraumatic stress disorder vulnerability. Rev Bras Psiquiatr, 2014; 36:89–94.
15.
YehudaR, DaskalakisNP, LehmerA, et al.Influences of maternal and paternal PTSD on epigenetic regulation of the glucocorticoid receptor gene in Holocaust survivor offspring. Am J Psychiatry, 2014; 171:872–880.
16.
YehudaR, EngelS, BrandSR, et al.Transgenerational effects of posttraumatic stress disorder in babies of mothers exposed to the World Trade Center attacks during pregnancy. J Clin Endocrinol Metab, 2005; 90:4115–4118.
17.
RosenfeldCS. Bisphenol A and phthalate endocrine disruption of parental and social behaviors. Front Neurosci, 2015; 9:5–7.
18.
XinF, SusiarjoM, BartolomeiMS. Multigenerational and transgenerational effects of endocrine disrupting chemicals: A role for altered epigenetic regulation?. Semin Cell Div Biol, 2015; May 28:e-pub ahead of print.
19.
CsabaG. Transgenerational effects of perinatal hormonal imprinting. In: TollefsbolT, ed. Transgenerational Epigenetics: Evidence and Debate. London: Academic Press, 2014:255–267.
20.
Paoloni-GiacobinoA. Epigenetic transgenerational inheritance of reproductive disease. In: TollefsbolT, ed. Transgenerational Epigenetics: Evidence and Debate. London: Academic Press, 2014:303–319.
21.
RyuHW, LeeDH, WonHR, et al.Influence of toxicologically relevant metals on human epigenetic regulation. Toxicol Res, 2015; 31:1–9.
22.
Gill SuperHJ. A role for epigenetics in the formation of chromosome translocations in acute leukemia. Cancer Genet, 2015; 208:230–236.
23.
UdaliS, GuariniP, RuzzenenteA, et al.DNA methylation and gene expression profiles show novel regulatory pathways in hepatocellular carcinoma. Clin Epigenetics, 2015; 7:4–3.
24.
Jiménez-ChillarónJC, DiazR, Ramón-KrauelM, RibóS. Transgenerational epigenetic inheritance of type 2 diabetes. In: TollefsbolT, ed. Epigenetics: Evidence and Debate. London: Academic Press, 2014; 281–299.
SchianoC, VietriMT, GrimaldiV, et al.Epigenetic-related therapeutic challenges in cardiovascular disease. Trends Pharmacol Sci, 2015; 36:226–235.
27.
LeeJH, FrisoS, ChoiSW. Epigenetic mechanism underlying the link between non-alcoholic fatty liver diseases and nutrition. Nutrients, 2014; 6:3303–3325.
28.
RoseboomT, PainterR. Epidemiology of transgenerational epigenetics. In: TollefsbolT, ed. Epigenetics: Evidence and Debate. London: Academic Press, 2014:59–66.
29.
NorthstoneK, GoldingJ, Davey SmithG, et al.Prepubertal start of father's smoking and increased body fat in his sons: Further characterisation of paternal transgenerational responses. Eur J Hum Genet, 2014; 22:1382–1386.
30.
SenN. Epigenetic regulation of memory by acetylation and methylation of chromatin: Implications in neurological disorders, aging, and addiction. Neuromolecular Med, 2015; 17:97–110.
31.
Mendioroz IriarteM, Pulido FontesL, Méndez-LópezI. Neuroepigenetics: Desoxyribonucleic [obsol] acid methylation in Alzheimer's disease and other dementias [in Spanish]. Med Clin (Barc), 2015; 144:457–464.
32.
KubotaT, HirasawaT, MiyakeK. Mental disorders and transgenerational epigenetics. In: TollefsbolT, ed. Epigenetics: Evidence and Debate. London: Academic Press, 2014:343–356.
33.
SarkerDK. Male germline transmits fetal alcohol epigenetic marks for multiple generations: A review. Addict Biol, 2015; January12:e-pub ahead of print.
34.
ZwillerJ. Epigenetics and drug addiction: A focus on MeCP2 and on histone acetylation [in French]. Med Sci (Paris), 2015; 31:439–446.
35.
RusieckiJA, ByrmeC, GaldzickiZ, et al.PTSD and DNA methylation in select immune function gene promoter regions: A repeated measures case-control study of U.S. military service members. Front Psychiatry, 2013; 4:5–6.
36.
LiuC, ChungM. Genetics and epigenetics of circadian rhythms and their potential roles in neuropsychiatric disorders. Neurosci Bull, 2015; 31:141–159.
37.
PicasciaA, GrimaldiV, PignalosaO, et al.Epigenetic control of autoimmune diseases: From bench to bedside. Clin Immunol, 2015; 157:1–15.
38.
MiaoCG, YangJT, YangYY, et al.Critical role of DNA methylation in the pathogenesis of systemic lupus erythematosus: New advances and future challenges. Lupus, 2014; 23:730–742.
39.
LeslieFM. Multigenerational epigenetic effects of nicotine on lung function. BMC Med, 2013; 11:2–7.
40.
NilssonE, SkinnerMK. Definition of epigenetic transgenerational inheritance and biological impacts. In: TollefsbolT, ed. Epigenetics: Evidence and Debate, London: Academic Press, 2014:11–16.
41.
KanherkarRR, Bhatia-DeyN, CsokaAB. Epigenetics across the human lifespan. Front Cell Dev Biol, 2014; 2:4–9.
42.
ThakurVS, DebG, BabcookMA, GuptaS. Plant phytochemicals as epigenetic modulators: Role in cancer chemoprevention. AAPS J, 2014; 16:151–163.
43.
NU-AGE. About NU-AGE. Online document at: www.nu-age.eu/about-project Accessed May23, 2015.
44.
Szarc vel SzicK, DeclerckK, VidakovićM, BergheWV. From inflammaging to healthy aging by dietary lifestyle choices: Is epigenetics the key to personalized nutrition?. Clin Epigenetics, 2015; 7:33.
45.
ShorterKR, FelderMR, VranaPB. Consequences of dietary methyl donor supplements: Is more always better?. Prog Biophys Mol Biol, 2015; 118(1–2):14–20.
46.
LecoutreS, BretonC. Maternal nutritional manipulations program adipose tissue dysfunction in offspring. Front Physiol, 2015; 6:15–8.
47.
DashwoodRH, HoE. Dietary histone deacetylase inhibitors: From cells to mice to men. Semin Cancer Biol, 2007; 17:363–369.
LindholmME, MarabitaF, Gomez-CabreroD, et al.An integrative analysis reveals coordinated reprogramming of the epigenome and the transcriptome in human skeletal muscle after training. Epigenetics, 2014; 9:1557–1569.
50.
HeSY, LuSF, ZhuBM. Progress of researches on mechanisms of acupuncture therapy underlying improving myocardial ischemia and the future approach for in-depth study on its mechanisms from epigenetics [in Chinese]. Zhen Ci Yan Jiu, 2014; 39:73–78.
51.
PizzimentiCL, LattalKM. Epigenetics and memory: Causes, consequences and treatments for post-traumatic stress disorder and addiction. Genes Brain Behav, 2015; 14:73–84.
52.
RasoolM, MalikA, NaseerMI, et al.The role of epigenetics in personalized medicine: Challenges and opportunities. BMC Med Genomics, 2015; 8(suppl1):S5.
53.
CadetJL, Epigenetics of stress, addiction, and resilience: Therapeutic implications. Mol Neurobiol, 2014; December11:e-pub ahead of print.
54.
BacaliniMG, FrisoS, OlivieriF, et al.Present and future of anti-ageing epigenetic diets. Mech Ageing Dev, 2014; 136–137:101–115.
55.
National Human Genome Research Institute. Epigenomics. Online document at: www.genome.gov/27532724 Accessed June6, 2015.